237 research outputs found

    Effects of High Energy Particle (HZE) Radiation on the Distal Lung

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    Major sources of concern for manned space travel are the effects of high energy particle (HZE) radiation on various biological systems, and the consequences of major solar activity. To date, considerable attention has been directed toward HZE-induced alterations both on non-dividing systems, such as the retina, cornea and brain, and on dividing systems, such as the gut and testis. This paper is focused on the morphologically detectable late-occurring alterations in the distal lung, and toward a comparison of the changes with those induced by x -irradiation. Briefly, the salient alterations involve an increase in 1) the width of the septal walls and the capillary and alveolar basal laminae, and 2) the irregularity of the luminal surface of the capillaries, as exemplified by the presence of filipodial projections and blebbing. All alterations were focal in their localization, and no cells of any type (e.g., epithelial, endothelial or stromal) appeared to undergo damage, an observation quite unlike the cellular changes induced by x-irradiation

    Suomen viljelymaiden pedologisia piirteitä ja maannoksia

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    A SWOT Analysis of the Use of Marine, Grain, Terrestrial-Animal and Novel Protein Ingredients in Aquaculture Feeds

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    A variety of new feed ingredients are emerging in the aquaculture feed sector. While the technology readiness of these options varies across and within the new ingredient classes, it remains important to consider them in terms of the overall feed ingredient spectrum. In this review, the use of marine, grain, terrestrial animal by-product and a range of novel (e.g., bacterial and yeast) resources being considered as potential protein feedstuffs for use in aquafeeds is explored. In comparing the nutritional attributes of each of the ingredient classes, an assessment framework is applied based on understanding the critical knowledge required to be able to accommodate any ingredient in a formulation process. To further examine each of the different ingredient classes a Strength-Weakness-Opportunity-and-Threats (SWOT) analysis is applied, to enable some consideration of what future potential may exist across the spectrum and what risks and opportunities they may bring. It is noted that all ingredients have strengths and weaknesses, and that there is no such thing as the perfect ingredient. By better appreciating the positives and negatives of each ingredient, it becomes possible to increase adaptability in responding to the various opportunities for their use in feeds

    A SWOT Analysis of the Use of Marine, Grain, Terrestrial-Animal and Novel Protein Ingredients in Aquaculture Feeds

    Get PDF
    A variety of new feed ingredients are emerging in the aquaculture feed sector. While the technology readiness of these options varies across and within the new ingredient classes, it remains important to consider them in terms of the overall feed ingredient spectrum. In this review, the use of marine, grain, terrestrial animal by-product and a range of novel (e.g., bacterial and yeast) resources being considered as potential protein feedstuffs for use in aquafeeds is explored. In comparing the nutritional attributes of each of the ingredient classes, an assessment framework is applied based on understanding the critical knowledge required to be able to accommodate any ingredient in a formulation process. To further examine each of the different ingredient classes a Strength-Weakness-Opportunity-and-Threats (SWOT) analysis is applied, to enable some consideration of what future potential may exist across the spectrum and what risks and opportunities they may bring. It is noted that all ingredients have strengths and weaknesses, and that there is no such thing as the perfect ingredient. By better appreciating the positives and negatives of each ingredient, it becomes possible to increase adaptability in responding to the various opportunities for their use in feeds

    Workgroup Report: Workshop on Source Apportionment of Particulate Matter Health Effects—Intercomparison of Results and Implications

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    Although the association between exposure to ambient fine particulate matter with aerodynamic diameter < 2.5 μm (PM(2.5)) and human mortality is well established, the most responsible particle types/sources are not yet certain. In May 2003, the U.S. Environmental Protection Agency’s Particulate Matter Centers Program sponsored the Workshop on the Source Apportionment of PM Health Effects. The goal was to evaluate the consistency of the various source apportionment methods in assessing source contributions to daily PM(2.5) mass–mortality associations. Seven research institutions, using varying methods, participated in the estimation of source apportionments of PM(2.5) mass samples collected in Washington, DC, and Phoenix, Arizona, USA. Apportionments were evaluated for their respective associations with mortality using Poisson regressions, allowing a comparative assessment of the extent to which variations in the apportionments contributed to variability in the source-specific mortality results. The various research groups generally identified the same major source types, each with similar elemental makeups. Intergroup correlation analyses indicated that soil-, sulfate-, residual oil-, and salt-associated mass were most unambiguously identified by various methods, whereas vegetative burning and traffic were less consistent. Aggregate source-specific mortality relative risk (RR) estimate confidence intervals overlapped each other, but the sulfate-related PM(2.5) component was most consistently significant across analyses in these cities. Analyses indicated that source types were a significant predictor of RR, whereas apportionment group differences were not. Variations in the source apportionments added only some 15% to the mortality regression uncertainties. These results provide supportive evidence that existing PM(2.5) source apportionment methods can be used to derive reliable insights into the source components that contribute to PM(2.5) health effects
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