947 research outputs found
Managing the Socially Marginalized: Attitudes Towards Welfare, Punishment and Race
Welfare and incarceration policies have converged to form a system of governance over socially marginalized groups, particularly racial minorities. In both of these policy areas, rehabilitative and social support objectives have been replaced with a more punitive and restrictive system. The authors examine the convergence in individual-level attitudes concerning welfare and criminal punishment, using national survey data. The authors\u27 analysis indicates a statistically significant relationship between punitive attitudes toward welfare and punishment. Furthermore, accounting for the respondents\u27 racial attitudes explains the bivariate relationship between welfare and punishment. Thus, racial attitudes seemingly link support for punitive approaches to opposition to welfare expenditures. The authors discuss the implications of this study for welfare and crime control policies by way of the conclusion
Piecing Together the American Voting Puzzle: How Votersâ Personalities and Judgments of Issue Importance Mattered in the 2016 Presidential Election
In the wake of the 2016 election, which surprised pundits and voters on both the left and the right, there has been renewed interest in understanding what predicts American votersâ choices. In this article, we investigate the roles of personality and issue importance in how people voted in the 2016 U.S. election. In this longitudinal study of 403 MTurk workers who voted in the election, we assessed the relations between personality (openness, social dominance orientation, and national identity importance) and issue importance (group rights and social justice, economic rights, and individual and national rights), and voting for Clinton or Trump. Our results indicate that both individual differences and issue importance as measured in July 2016 predicted votes in November. We also found that the links between personality and voting were mediated by issue importance. Implications for political psychology and the study of personality, campaign issues, and voting behavior are discussed.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146841/1/asap12157.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/146841/2/asap12157_am.pd
High Temperature Matter and Gamma Ray Spectra from Microscopic Black Holes
The relativistic viscous fluid equations describing the outflow of high
temperature matter created via Hawking radiation from microscopic black holes
are solved numerically for a realistic equation of state. We focus on black
holes with initial temperatures greater than 100 GeV and lifetimes less than 6
days. The spectra of direct photons and photons from decay are
calculated for energies greater than 1 GeV. We calculate the diffuse gamma ray
spectrum from black holes distributed in our galactic halo. However, the most
promising route for their observation is to search for point sources emitting
gamma rays of ever-increasing energy.Comment: 33 pages, 13 figures, to be submitted to PR
Dynamics of liquid 4He in Vycor
We have measured the dynamic structure factor of liquid 4He in Vycor using
neutron inelastic scattering. Well-defined phonon-roton (p-r) excitations are
observed in the superfluid phase for all wave vectors 0.3 < Q < 2.15. The p-r
energies and lifetimes at low temperature (T = 0.5 K) and their temperature
dependence are the same as in bulk liquid 4He. However, the weight of the
single p-r component does not scale with the superfluid fraction (SF) as it
does in the bulk. In particular, we observe a p-r excitation between T_c =
1.952 K, where SF = 0, and T_(lambda)=2.172 K of the bulk. This suggests, if
the p-r excitation intensity scales with the Bose condensate, that there is a
separation of the Bose-Einstein condensation temperature and the superfluid
transition temperature T_c of 4He in Vycor. We also observe a two-dimensional
layer mode near the roton wave vector. Its dispersion is consistent with
specific heat and SF measurements and with layer modes observed on graphite
surfaces.Comment: 3 pages, 4 figure
Complete-Graph Tensor Network States: A New Fermionic Wave Function Ansatz for Molecules
We present a new class of tensor network states that are specifically
designed to capture the electron correlation of a molecule of arbitrary
structure. In this ansatz, the electronic wave function is represented by a
Complete-Graph Tensor Network (CGTN) ansatz which implements an efficient
reduction of the number of variational parameters by breaking down the
complexity of the high-dimensional coefficient tensor of a
full-configuration-interaction (FCI) wave function. We demonstrate that CGTN
states approximate ground states of molecules accurately by comparison of the
CGTN and FCI expansion coefficients. The CGTN parametrization is not biased
towards any reference configuration in contrast to many standard quantum
chemical methods. This feature allows one to obtain accurate relative energies
between CGTN states which is central to molecular physics and chemistry. We
discuss the implications for quantum chemistry and focus on the spin-state
problem. Our CGTN approach is applied to the energy splitting of states of
different spin for methylene and the strongly correlated ozone molecule at a
transition state structure. The parameters of the tensor network ansatz are
variationally optimized by means of a parallel-tempering Monte Carlo algorithm
Development and characterization of a Yucatan miniature biomedical pig permanent middle cerebral artery occlusion stroke model
BACKGROUND: Efforts to develop stroke treatments have met with limited success despite an intense need to produce novel treatments. The failed translation of many of these therapies in clinical trials has lead to a close examination of the therapeutic development process. One of the major factors believed to be limiting effective screening of these treatments is the absence of an animal model more predictive of human responses to treatments. The pig may potentially fill this gap with a gyrencephalic brain that is larger in size with a more similar gray-white matter composition to humans than traditional stroke animal models. In this study we develop and characterize a novel pig middle cerebral artery occlusion (MCAO) ischemic stroke model. METHODS: Eleven male pigs underwent MCAO surgery with the first 4 landrace pigs utilized to optimize stroke procedure and 7 additional Yucatan stroked pigs studied over a 90 day period. MRI analysis was done at 24 hrs and 90 days and included T2w, T2w FLAIR, T1w FLAIR and DWI sequences and associated ADC maps. Pigs were sacrificed at 90 days and underwent gross and microscopic histological evaluation. Significance in quantitative changes was determined by two-way analysis of variance and post-hoc Tukey’s Pair-Wise comparisons. RESULTS: MRI analysis of animals that underwent MCAO surgery at 24 hrs had hyperintense regions in T2w and DWI images with corresponding ADC maps having hypointense regions indicating cytotoxic edema consistent with an ischemic stroke. At 90 days, region of interest analysis of T1 FLAIR and ADC maps had an average lesion size of 59.17 cc, a loss of 8% brain matter. Histological examination of pig brains showed atrophy and loss of tissue, consistent with MRI, as well as glial scar formation and macrophage infiltration. CONCLUSIONS: The MCAO procedure led to significant and consistent strokes with high survivability. These results suggest that the pig model is potentially a robust system for the study of stroke pathophysiology and potential diagnostics and therapeutics
Phase phonon spectrum and melting in a quantum rotor model with diagonal disorder
We study the zero-temperature () quantum rotor model with on-site
disorder in the charging energy. Such a model may serve as an idealized
Hamiltonian for an array of Josephson-coupled small superconducting grains, or
superfluid He in a disordered environment. In the approximation of
small-amplitude phase fluctuations, the Hamiltonian maps onto a system of
coupled harmonic oscillators with on-site disorder. We study the effects of
disorder in this harmonic regime, using the coherent potential approximation
(CPA), obtaining the density of states and the lifetimes of the spin-wave-like
excitations for several choices of the parameters which characterize the
disorder. Finally, we estimate the parameters characterizing the
quantum melting of the phase order, using a suitable Lindemann criterion.Comment: 8 pages, 5 figures. To be published in Phys. Rev. B. Minor change
Use of KikGR a photoconvertible green-to-red fluorescent protein for cell labeling and lineage analysis in ES cells and mouse embryos
<p>Abstract</p> <p>Background</p> <p>The use of genetically-encoded fluorescent proteins has revolutionized the fields of cell and developmental biology and in doing so redefined our understanding of the dynamic morphogenetic processes that shape the embryo. With the advent of more accessible and sophisticated imaging technologies as well as an abundance of fluorescent proteins with different spectral characteristics, the dynamic processes taking place <it>in situ </it>in living cells and tissues can now be probed. Photomodulatable fluorescent proteins are one of the emerging classes of genetically-encoded fluorescent proteins.</p> <p>Results</p> <p>We have compared PA-GFP, PS-CFP2, Kaede and KikGR four readily available and commonly used photomodulatable fluorescent proteins for use in ES cells and mice. Our results suggest that the green-to-red photoconvertible fluorescent protein, Kikume Green-Red (KikGR), is most suitable for cell labeling and lineage studies in ES cells and mice because it is developmentally neutral, bright and undergoes rapid and complete photoconversion. We have generated transgenic ES cell lines and strains of mice exhibiting robust widespread expression of KikGR. By efficient photoconversion of KikGR we labeled subpopulations of ES cells in culture, and groups of cells within <it>ex utero </it>cultured mouse embryos. Red fluorescent photoconverted cells and their progeny could be followed for extended periods of time.</p> <p>Conclusion</p> <p>Transgenic ES cells and mice exhibiting widespread readily detectable expression of KikGR are indistinguishable from their wild type counterparts and are amenable to efficient photoconversion. They represent novel tools for non-invasive selective labeling specific cell populations and live imaging cell dynamics and cell fate. Genetically-encoded photomodulatable proteins such as KikGR represent emergent attractive alternatives to commonly used vital dyes, tissue grafts and genetic methods for investigating dynamic behaviors of individual cells, collective cell dynamics and fate mapping applications.</p
‘It makes me feel alive’: the socio-motivational impact of drama and theatre on marginalised young people
An in-depth, longitudinal, idiographic study examined the impact of theatre and drama involvement on marginalised young people. Semi-structured interviews, at three separate time points over 2 years, were conducted with four young people (15–21 years of age) involved in a theatre project. Interpretative phenomenological analysis suggested that drama and theatre create space and support for the authentic self, and provide optimal conditions for promoting growth and resilience through voluntary engagement in a positive activity. In particular, the analysis highlighted the pivotal role of interpersonal relationships and a nurturing environment in re-engaging young people. Some participants’ accounts also suggested that drama provides a uniquely engaging and therapeutic way to reflect on, express and explore experiences. The results are discussed in relation to core psychological processes underpinning self-development and key directions for further research
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