Magnetotransport in polycrystalline La2/3_{2/3}Sr1/3_{1/3}MnO3_{3} thin films of controlled granularity

Polycrystalline La$_{2/3}$Sr$_{1/3}$MnO$_{3}$ (LSMO) thin films were synthesized by pulsed laser ablation on single crystal (100) yttria-stabilized zirconia (YSZ) substrates to investigate the mechanism of magneto-transport in a granular manganite. Different degrees of granularity is achieved by using the deposition temperature (T$_{D}$) of 700 and 800 $^{0}$C. Although no significant change in magnetic order temperature (T$_C$) and saturation magnetization is seen for these two types of films, the temperature and magnetic field dependence of their resistivity ($\rho$(T, H)) is strikingly dissimilar. While the $\rho$(T,H) of the 800 $^{0}$C film is comparable to that of epitaxial samples, the lower growth temperature leads to a material which undergoes insulator-to-metal transition at a temperature (T$_{P}$ $\approx$ 170 K) much lower than T$_C$. At T $\ll$ T$_P$, the resistivity is characterized by a minimum followed by ln \emph{T} divergence at still lower temperatures. The high negative magnetoresistance ($\approx$ 20$$) and ln \emph{T} dependence below the minimum are explained on the basis of Kondo-type scattering from blocked Mn-spins in the intergranular material. Further, a striking feature of the T$_D$ = 700 $^{0}$C film is its two orders of magnitude larger anisotropic magnetoresistance (AMR) as compared to the AMR of epitaxial films. We attribute it to unquenching of the orbital angular momentum of 3d electrons of Mn ions in the intergranular region where crystal field is poorly defined.Comment: 26 pages, 7 figure

A normalisation procedure for biaxial bias extension tests

Biaxial Bias Extension tests have been performed on a plain-weave carbon fibre engineering fabric. The test results have been normalised using both the upper and lower bound method proposed by Potluri et al. and also using a novel alternative normalisation method based on energy arguments. The normalised results from both methods are compared and discussed

Cardiac Spheroids as in vitro Bioengineered Heart Tissues to Study Human Heart Pathophysiology.

Despite several advances in cardiac tissue engineering, one of the major challenges to overcome remains the generation of a fully functional vascular network comprising several levels of complexity to provide oxygen and nutrients within bioengineered heart tissues. Our laboratory has developed a three-dimensional in vitro model of the human heart, known as the "cardiac spheroid" or "CS". This presents biochemical, physiological, and pharmacological features typical of the human heart and is generated by co-culturing its three major cell types, such as cardiac myocytes, endothelial cells, and fibroblasts. Human induced pluripotent stem cells-derived cardiomyocytes (hiPSC-CMs or iCMs) are co-cultured at ratios approximating the ones found in vivo with human cardiac fibroblasts (HCFs) and human coronary artery endothelial cells (HCAECs) in hanging drop culture plates for three to four days. The confocal analysis of CSs stained with antibodies against cardiac Troponin T, CD31 and vimentin (markers for cardiac myocytes, endothelial cells and fibroblasts, respectively) shows that CSs present a complex endothelial cell network, resembling the native one found in the human heart. This is confirmed by the 3D rendering analysis of these confocal images. CSs also present extracellular matrix (ECM) proteins typical of the human heart, such as collagen type IV, laminin and fibronectin. Finally, CSs present a contractile activity measured as syncytial contractility closer to the one typical of the human heart compared to CSs that contain iCMs only. When treated with a cardiotoxic anti-cancer agent, such as doxorubicin (DOX, used to treat leukemia, lymphoma and breast cancer), the viability of DOX-treated CSs is significantly reduced at 10 µM genetic and chemical inhibition of endothelial nitric oxide synthase, a downstream target of DOX in HCFs and HCAECs, reduced its toxicity in CSs. Given these unique features, CSs are currently used as in vitro models to study heart biochemistry, pathophysiology, and pharmacology

Snow cover, snowmelt and runoff in the Himalayan River basins

Not withstanding the seasonal vagaries of both rainfall amount and snowcover extent, the Himalayan rivers retain their basic perennial character. However, it is the component of snowmelt yield that accounts for some 60 to 70 percent of the total annual flow volumes from Hamilayan watersheds. On this large hydropotential predominantly depends the temporal performance of hydropower generation and major irrigation projects. The large scale effects of Himalayan snowcover on the hydrologic responses of a few selected catchments in western Himalayas was studied. The antecedent effects of snowcover area on long and short term meltwater yields can best be analyzed by developing appropriate hydrologic models forecasting the pattern of snowmelt as a function of variations in snowcover area. It is hoped that these models would be of practical value in the management of water resources. The predictability of meltwater for the entire snowmelt season was studied, as was the concurrent flow variation in adjacent watersheds, and their hydrologic significance. And the applicability of the Snowmelt-Runoff Model for real time forecast of daily discharges during the major part of the snowmelt season is examined

Energy efficient engine: Low-pressure turbine subsonic cascade component development and integration program

A subsonic cascade test program was conducted to provide technical data for optimizing the blade and vane airfoil designs for the Energy Efficient Engine Low-Pressure Turbine component. The program consisted of three parts. The first involved an evaluation of the low-chamber inlet guide vane. The second, was an evaluation of two candidate aerodynamic loading philosophies for the fourth blade root section. The third part consisted of an evaluation of three candidate airfoil geometries for the fourth blade mean section. The performance of each candidate airfoil was evaluated in a linear cascade configuration. The overall results of this study indicate that the aft-loaded airfoil designs resulted in lower losses which substantiated Pratt & Whitney Aircraft's design philosophy for the Energy Efficient Engine low-pressure turbine component

Semiclassical ordering in the large-N pyrochlore antiferromagnet

We study the semiclassical limit of the $Sp(N)$ generalization of the pyrochlore lattice Heisenberg antiferromagnet by expanding about the $N \to \infty$ saddlepoint in powers of a generalized inverse spin. To leading order, we write down an effective Hamiltonian as a series in loops on the lattice. Using this as a formula for calculating the energy of any classical ground state, we perform Monte-Carlo simulations and find a unique collinear ground state. This state is not a ground state of linear spin-wave theory, and can therefore not be a physical (N=1) semiclassical ground state.Comment: 4 pages, 4 eps figures; published versio