6 research outputs found
Synthesis and characterization of some novel isoxazolines and pyrazolines as potent antimicrobial agents
No full text879-884The title compounds 4a-h and 5a-h, have been prepared
starting from chalcones 3a-h having 5-chlorothiophene moiety. Chalcones 3a-h react with hydroxylamine
hydrochloride in presence of alkali to afford isoxazolines 4a-h. Further
3a-h react with hydrazine hydrate in presence of glacial acetic acid to
give pyrazolines 5a-h. The structures of newly synthesized compounds
have been confirmed by elemental analysis as well as IR, 1H NMR and
mass spectral data. The newly synthesized compounds have been screened for
their antimicrobial activity. Some of the compounds show moderate antimicrobial
activity as compared to the known reference drugs Gentamycin, Cefixime and
Ketoconazole
Novel 1,3-diarylpyrazole acrylamides: synthesis, antiplatelet activity screening, and in silico evaluation studies
No full textMolybdenum anchored onto zeolite beta: an efficient catalyst for the one-pot synthesis of octahydroquinazolinone derivatives under solvent-free conditions
No full text
