34 research outputs found
Caractérisation des processus hydrologiques sur le super-site de la Donga : haut bassin de l'Ouémé (Bénin), ORE AMMA-CATCH
Tsukushi Modulates Xnr2, FGF and BMP Signaling: Regulation of Xenopus Germ Layer Formation
Cell-cell communication is essential in tissue patterning. In early amphibian development, mesoderm is formed in the blastula-stage embryo through inductive interactions in which vegetal cells act on overlying equatorial cells. Members of the TGF-beta family such as activin B, Vg1, derriĂšre and Xenopus nodal-related proteins (Xnrs) are candidate mesoderm inducing factors, with further activity to induce endoderm of the vegetal region. TGF-beta-like ligands, including BMP, are also responsible for patterning of germ layers. In addition, FGF signaling is essential for mesoderm formation whereas FGF signal inhibition has been implicated in endoderm induction. Clearly, several signaling pathways are coordinated to produce an appropriate developmental output; although intracellular crosstalk is known to integrate multiple pathways, relatively little is known about extracellular coordination
Comprehensive Gene-Expression Survey Identifies Wif1 as a Modulator of Cardiomyocyte Differentiation
During chicken cardiac development the proepicardium (PE) forms the epicardium (Epi), which contributes to several non-myocardial lineages within the heart. In contrast to Epi-explant cultures, PE explants can differentiate into a cardiomyocyte phenotype. By temporal microarray expression profiles of PE-explant cultures and maturing Epi cells, we identified genes specifically associated with differentiation towards either of these lineages and genes that are associated with the Epi-lineage restriction. We found a central role for Wnt signaling in the determination of the different cell lineages. Immunofluorescent staining after recombinant-protein incubation in PE-explant cultures indicated that the early upregulated Wnt inhibitory factor-1 (Wif1), stimulates cardiomyocyte differentiation in a similar manner as Wnt stimulation. Concordingly, in the mouse pluripotent embryogenic carcinoma cell line p19cl6, early and late Wif1 exposure enhances and attenuates differentiation, respectively. In ovo exposure of the HH12 chicken embryonic heart to Wif1 increases the Tbx18-positive cardiac progenitor pool. These data indicate that Wif1 enhances cardiomyogenesis
Novel participatory indicators of sustainability reveal weaknesses of maize cropping in Benin
âIntestinimonas massiliensisâ sp. nov, a new bacterium isolated from human gut
Here we report the main features of the proposed new bacterial species âIntestinimonas massiliensisâ sp. nov. The type strain GD2T (CSUR=P1930) was isolated from the gut microbiota of a healthy patient using a culturomics approach combined with taxonogenomics
âBacillus massiliglacieiâ, a new bacterial species isolated from Siberian permafrost
We describe here the main characteristics of a new species isolated from Siberian permafrost dated around 10 million years. This species was named âBacillus massiliglacieiâ strain Marseille-P2600T (= CSUR P2600=DSM 102861)
Pseudoruminococcus massiliensis gen. nov., sp. nov., a new bacterium isolated from the human gut microbiota
International audienc
Dialister massiliensis sp. nov., a new bacterium isolated from the human gut
International audienc