Alcohol Consumption in the Colombian Population, 2015 National Mental Health Survey

Introducción La Encuesta Nacional de Salud Mental (ENSM) de 2015 indagó en Colombia, entre otros asuntos, sobre el de consumo de alcohol de las personas entre 12 y 17 años y de 18 y más años. Se presentaron los datos según edad y región, sin realizar cruces con otras variables de salud mental, problemas, trastornos, acceso a servicios, estados de salud y su valoración. Objetivo Evaluar la prevalencia del consumo de alcohol en la población colombiana de edad ≥ 12 años teniendo en cuenta las variables sociodemográficas y el cribado clínico. Métodos Análisis secundario de base de datos de la ENSM 2015; constituyeron la muestra 15.231 personas de 12 a 96 años de 13.200 hogares de cinco regiones del país (Atlántica, Bogotá, Central, Oriental y Pacífica). Se usó el Alcohol and Use Disorder Identification Test, corto y completo (AUDIT y AUDIT-C), con análisis estratificado según puntuación y otras variables incluidas en la encuesta. Resultados El 2,7% de los menores estudiados entran en la categoría de bebedor de riesgo. El mayor porcentaje de bebedores de riesgo se ubica en la franja de 18 a 44 años, con clara mayoría de varones. Conclusiones El estudio encuentra que un AUDIT-C positivo en mayores de edad se asocia con mayor porcentaje de no presentar síntomas ansiedad y menos problemas de ansiedad, eventos traumáticos y eventos traumáticos por conflicto armado reportados. Esto requiere más estudios. Las personas adultas con AUDIT-C positivo tienen mayor percepción de bienestar, aunque también se halla mayor porcentaje de hogares en estado de pobreza. El estudio de factores individuales, sociales, familiares y ambientales en poblaciones específicas se debe desarrollar para realizar intervenciones más adecuadas.Q476-88Introduction National Survey of Mental Health (ENSM) in 2015 in Colombia asks, among other conditions, about alcohol consumption in people 12-17 years old, and 18 and older. Data were presented by age and region, with no cross-references to other categories of mental health problems, disorders, access to services, and health status. Objective To assess alcohol consumption in Colombia, taking into account sociodemographic and clinical screening categories included. Methods Secondary database analysis, sample size: 15,231 people from 13,200 households of five regions (Atlantic, Bogotá, Central, Eastern, and Pacific), with an age range from 12 to 96 years. AUDIT and AUDIT-C were used and stratified according to score and other variables included in the survey analysis. Results The high-risk drinking category was observed in 2.7% of children studied, with the highest percentage of drinking risk lying in the range of 18 to 44 years, with a clear majority of men. Conclusions The study finds that a positive AUDIT-C in adults is associated with a higher percentage of non-anxiety, less anxiety problems, and traumatic events and traumatic events related to armed conflict. This requires further studies. Adults with positive AUDIT-C have a greater perception of well-being, but also a higher percentage of households in poverty. The study of individual, social, family and environmental factors in specific populations should be developed in order to make more appropriate interventions

Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study

Background Results from retrospective studies suggest that use of neuromuscular blocking agents during general anaesthesia might be linked to postoperative pulmonary complications. We therefore aimed to assess whether the use of neuromuscular blocking agents is associated with postoperative pulmonary complications. Methods We did a multicentre, prospective observational cohort study. Patients were recruited from 211 hospitals in 28 European countries. We included patients (aged ≥18 years) who received general anaesthesia for any in-hospital procedure except cardiac surgery. Patient characteristics, surgical and anaesthetic details, and chart review at discharge were prospectively collected over 2 weeks. Additionally, each patient underwent postoperative physical examination within 3 days of surgery to check for adverse pulmonary events. The study outcome was the incidence of postoperative pulmonary complications from the end of surgery up to postoperative day 28. Logistic regression analyses were adjusted for surgical factors and patients’ preoperative physical status, providing adjusted odds ratios (ORadj) and adjusted absolute risk reduction (ARRadj). This study is registered with ClinicalTrials.gov, number NCT01865513. Findings Between June 16, 2014, and April 29, 2015, data from 22803 patients were collected. The use of neuromuscular blocking agents was associated with an increased incidence of postoperative pulmonary complications in patients who had undergone general anaesthesia (1658 [7·6%] of 21694); ORadj 1·86, 95% CI 1·53–2·26; ARRadj –4·4%, 95% CI –5·5 to –3·2). Only 2·3% of high-risk surgical patients and those with adverse respiratory profiles were anaesthetised without neuromuscular blocking agents. The use of neuromuscular monitoring (ORadj 1·31, 95% CI 1·15–1·49; ARRadj –2·6%, 95% CI –3·9 to –1·4) and the administration of reversal agents (1·23, 1·07–1·41; –1·9%, –3·2 to –0·7) were not associated with a decreased risk of postoperative pulmonary complications. Neither the choice of sugammadex instead of neostigmine for reversal (ORadj 1·03, 95% CI 0·85–1·25; ARRadj –0·3%, 95% CI –2·4 to 1·5) nor extubation at a train-of-four ratio of 0·9 or more (1·03, 0·82–1·31; –0·4%, –3·5 to 2·2) was associated with better pulmonary outcomes. Interpretation We showed that the use of neuromuscular blocking drugs in general anaesthesia is associated with an increased risk of postoperative pulmonary complications. Anaesthetists must balance the potential benefits of neuromuscular blockade against the increased risk of postoperative pulmonary complications

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

non present