Algunos efectos de la industrialización en Apopa

En el presente trabajo de graduación, mediante un estudio exploratorio y descriptivo se da a conocer el proceso de industrialización de Apopa operado entre 1950 y 1970, algunos algunos efectos de dicho proceso de industrialización en la vida de la comunidad y la formulación de una metodología que pudiera ser utilizada en otros estudios similares

Modelos garch con innovaciones con colas pesadas: aplicación empírica a la volatilidad de los mercados de acciones y de divisas en países con ingresos altos y latinoamericanos

En este trabajo se utilizan datos diarios de los mercados de acciones y divisas para estimar los modelos GARCH y GJR comparando países emergentes con países de altos ingresos. En ambos modelos, se toma la distribución Normal como base y se consideran distribuciones con colas pesadas: la distribución t-Student, la distribución GED, la distribución NIG y la distribución NRIG, tanto en su versiones simétricas como asimétricas para capturar las características de los retornos. Los principales resultados son los siguientes: (i) en todos los mercados y países se seleccionan modelos con distribuciones de colas pesadas: t-Student (S) y error generalizada (GED); (ii) es importante incluir efecto apalancamiento para el mercado de acciones, pero esto no es concluyente para el mercado de divisas; (iii) incorporar una distribución asimétrica en los retornos resulta necesario para todos los mercados de acciones, aunque esto no es necesario para algunos mercados de divisas.This paper uses daily data from stock and Forex markets in order to estimate GARCH and GJR models comparing emerging countries with high-income countries. In both models, the Normal distribution is taken as the basis and some heavy-tailed distributions are considered: the Student t-distribution, the GED distribution, the NIG distribution and the NRIG distribution, all in their symmetric and skewed versions to capture the characteristics of the returns. The main results are as follows: (i) in all markets and countries, models with heavy-tailed distributions are selected: Student’s t (S) and generalized error (GED); (ii) it is important to include the leverage effect for stock markets, but this is not conclusive for the Forex markets; (iii) incorporating an asymmetric distribution in returns is necessary for all equity markets, although this is not necessary for some currency markets

Optimal Placement and sizing of D-STATCOM in radial and meshed distribution networks using a discrete-continuous version of the genetic algorithm

In this paper, we propose a new discrete-continuous codification of the Chu–Beasley genetic algorithm to address the optimal placement and sizing problem of the distribution static compensators (D-STATCOM) in electrical distribution grids. The discrete part of the codification determines the nodes where D-STATCOM will be installed. The continuous part of the codification regulates their sizes. The objective function considered in this study is the minimization of the annual operative costs regarding energy losses and installation investments in D-STATCOM. This objective function is subject to the classical power balance constraints and devices’ capabilities. The proposed discrete-continuous version of the genetic algorithm solves the mixed-integer non-linear programming model that the classical power balance generates. Numerical validations in the 33 test feeder with radial and meshed configurations show that the proposed approach effectively minimizes the annual operating costs of the grid. In addition, the GAMS software compares the results of the proposed optimization method, which allows demonstrating its efficiency and robustnes

Prototipo de sistema basado en conocimientos para entrenamiento inteligente orientado a la evaluación académica “SEI”

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Frailty level prediction in older age using hand grip strength functions over time

This version of the article has been accepted for publication, after peer review and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/978-3-030-85099-9_29.Frailty syndrome can be defined as a clinical state in which there is a rise in individual vulnerability, developing an increase in both the dependence of the person and mortality. Frailty is completely related to age. A fundamental factor to apply rehabilitative interventions successfully resides in having a simple and reliable method capable of identifying frailty syndrome. Frailty indexes (FI) have several sources of uncertainty trough the opinion of the patients, white coat effect and external factors. Moreover, in the clinical practice, the experience of the geriatricians led them to determine an approximation of the frailty level only with a simple handshake. Hand grip strength (HGS) has been widely used in tests by investigators and therapists to be able to diagnose sarcopenia and frailty, as it is a reliable indicator of the overall muscle strength, which decreases with age. Most researches focused mainly on peak HGS, which will not give insight on how the patient’s strength was distributed over time. In the present work it is proposed to evaluate HGS behavior over a period of time, and to develop a system based on Machine Learning for the identification of frailty levels using physiological features, FI and the classical signal processing based on statistics of the HGS signals. The starting hypothesis is that it can be identified the “way” of performing HGS correlated with the level of frailty. To achieve this goal a clinical study was designed and carried out with a cohort of 70 elderly persons, in two Hospitals.This work was partially supported by the Spanish Ministry of Ciencia, Innovación y Universidades under project RTI2018-096701-B-C22, and by the Catalonia FEDER program, resolution GAH/815/2018 under the project, PECT Garraf : Envelliment actiu i saludable i dependència.Peer ReviewedPostprint (author's final draft

Respuesta del cultivo de la lechuga (lactuca sativa, l.) a la aplicación de dos bioproductos (Original)

The research was conducted in a Pardo ócrico sin carbonato soil without developed on igneous rocks in the CCS Frank País municipality Majibacoa, Las Tunas in the months of February and March 2016 with the objective of evaluating the effect of one stimulators of plant growth (Fitomas E) and biofertilizer EcoMic in morphological and productive variables in lettuce (Lactuca sativa, L.) cultivar Black Seeded Simpson. Was utilized an experimental design of blocks at random with eight treatments and four replies. The examined variables matched: height of the plant, length of the root, diameter of the stem, number of leaf for plants, mass of the plant and yield (kg m-2).  A double classification variance analysis was performed with the Infostat statistical package, version 2016.The cultivation of the lettuce responded positively to the stimulators of the vegetable growth application and to the EcoMic in all the evaluated variables. The bigger performances, minor costs for weights and bigger profits got with the independent use from EcoMic and EcoMic combination themselves FitoMas E. The use of these alternatives is recommended to contribute to sustainable crop production.La investigación se desarrolló en un suelo Pardo ócrico sin carbonato desarrollado sobre rocas ígneas en la CCS Frank País del municipio Majibacoa, Las Tunas entre los meses de febrero y marzo de 2016 con el objetivo de evaluar el efecto de un estimulador del crecimiento vegetal (FitoMas E) y el biofertilizante EcoMic en variables morfológicas y productivas en la lechuga (Lactuca sativa, L.) cultivar Black Seeded Simpson. Se utilizó un diseño experimental de bloques al azar con cuatro tratamientos y cinco réplicas. Las variables analizadas fueron: altura de la planta, largo de la raíz, diámetro del tallo, número de hojas por plantas, masa de la planta y rendimiento agrícola (kg m-2). Se realizó el análisis económico por el método comparativo. A los datos obtenidos se le realizó un análisis de varianza de clasificación doble con el paquete estadístico Infostat versión 2016. Los mejores resultados en la mayoría de las variables analizadas se obtuvieron con el uso independiente de EcoMic y la combinación de EcoMic + FitoMas E. Se recomienda el empleo de estas alternativas para contribuir a la producción sostenible del cultivo

FooDrugs: a comprehensive food–drug interactions database with text documents and transcriptional data

Food–drug interactions (FDIs) occur when a food item alters the pharmacokinetics or pharmacodynamics of a drug. FDIs can be clinically relevant, as they can hamper or enhance the therapeutic effects of a drug and impact both their efficacy and their safety. However, knowledge of FDIs in clinical practice is limited. This is partially due to the lack of resources focused on FDIs. Here, we describe FooDrugs, a database that centralizes FDI knowledge retrieved from two different approaches: a natural processing language pipeline that extracts potential FDIs from scientific documents and clinical trials and a molecular similarity approach based on the comparison of gene expression alterations caused by foods and drugs. FooDrugs database stores a total of 3 430 062 potential FDIs, with 1 108 429 retrieved from scientific documents and 2 321 633 inferred from molecular data. This resource aims to provide researchers and clinicians with a centralized repository for potential FDI information that is free and easy to use

LA ACCIÓN DE INCONSTITUCIONALIDAD Y EL CIUDADANO DENTRO DE UN ESTADO GARANTISTA

Para determinar si la exigencia argumentativa deprecada por la Corte Constitucional no vulnera garantías esenciales del estado Constitucional y democrático de derecho, es menester analizar i) la concepción del derecho a la tutela judicial efectiva, ii) el principio pro actione que de él se deriva iii) la finalidad de que una sea acción pública y iv) cómo estos conceptos se aplican en la realidad jurídica constitucional

LA ACCIÓN DE INCONSTITUCIONALIDAD Y EL CIUDADANO DENTRO DE UN ESTADO GARANTISTA

Para determinar si la exigencia argumentativa deprecada por la Corte Constitucional no vulnera garantías esenciales del estado Constitucional y democrático de derecho, es menester analizar i) la concepción del derecho a la tutela judicial efectiva, ii) el principio pro actione que de él se deriva iii) la finalidad de que una sea acción pública y iv) cómo estos conceptos se aplican en la realidad jurídica constitucional