A Practical Example for Model-Driven Web Requirements

The number of approaches for Web environments has grown very fast in the last years: HDM, OOHDM, and WSDM were among the first, and now a large number can be found in the literature. With the definition of MDA (Model- Driven Architecture) and the acceptance of MDE (Model-Driven Engineering) techniques in this environment, some groups are working in the use of metamodels and transformations to make their approaches more powerful. UWE (UMLBased Web Engineering) or OOWS (Object-Oriented Web Solutions) are only some examples. However, there are few real experiences with Web Engineering in the enterprise environment, and very few real applications of metamodels and MDE techniques. In this chapter the practical experience of a Web Engineering approach, NDT, in a big project developed in Andalusia is presented. Besides, it shows the usability of metamodels in real environments

A Practical Environment to Apply Model-Driven Web Engineering

The application of a model-driven paradigm in the development of Web Systems has yielded very good research results. Several research groups are defining metamodels, transformations, and tools which offer a suitable environment, known as model-driven Web engineering (MDWE). However, there are very few practical experiences in real Web system developments using real development teams. This chapter presents a practical environment of MDWE based on the use of NDT (navigational development techniques) and Java Web systems, and it provides a practical evaluation of its application within a real project: specialized Diraya.Ministerio de Educación y Ciencia TIN2007-67843-C06-03Ministerio de Educación y Ciencia TIN2007-30391-

Evaluación multidisciplinar 3D de una estructura kárstica asociada a colapso y subsidencia (Cuenca del Ebro)

La propagación de cavidades de disolución localizadas por debajo de series aluviales genera una serie de evidencias cuya representación superficial, en ocasiones, puede no ser indicativa de su extensión real en profundidad. La propagación de cavidades a través de medios heterogéneos, en los que pueden existir niveles cementados, puede producir cambios en la progresión de dichas cavidades y la identificación en superficie de grietas, colapsos, o zonas de subsidencia que pueden involucrar decenas de miles de metros cúbicos de material inestable. Cualquier tipo de evaluación de soluciones mitigadoras en estos contextos debe considerar la amplitud de estos volúmenes y el origen del proceso con independencia de la actividad registrada en superficie. En este trabajo se aborda un estudio integrado con el objetivo de determinar la estructura de un sector con evidencias de actividad kárstica superficial y evaluar su extensión y desarrollo tridimensional integrando el análisis geomorfológico, de inspección de campo, geofísica (GPR) y sondeos. The propagation of solution cavities located below alluvial deposits produce surficial evidences that, in some cases, cannot be representative of their actual extension at depth. Cavity propagation through heterogeneous media, for example with interbedded cemented levels, can produce changes in the propagation of deformation producing the identification of cracks, collapses or subsidence zones at the surface. These processes can involve thousands of cubic meters of unstable materials. Any evaluation of mitigation tasks, in this context, needs to consider: i) the amplitude of the affected volumes and ii) the in depth origin with independence of the surficial recorded activity In this work an integrated analysis is developed to evaluate the size and 3D structure of a sector with surficial evidences of karstic activity integrating geomorphological analysis, field inspection, geophysics (GPR) and boreholes

Holomorphic linearization of commuting germs of holomorphic maps

Let $f_1, ..., f_h$ be $h\ge 2$ germs of biholomorphisms of \C^n fixing the origin. We investigate the shape a (formal) simultaneous linearization of the given germs can have, and we prove that if $f_1, ..., f_h$ commute and their linear parts are almost simultaneously Jordanizable then they are simultaneously formally linearizable. We next introduce a simultaneous Brjuno-type condition and prove that, in case the linear terms of the germs are diagonalizable, if the germs commutes and our Brjuno-type condition holds, then they are holomorphically simultaneously linerizable. This answers to a multi-dimensional version of a problem raised by Moser.Comment: 24 pages; final version with erratum (My original paper failed to cite the work of L. Stolovitch [ArXiv:math/0506052v2]); J. Geom. Anal. 201

Structural disorder in plant proteins : where plasticity meets sessility

Plants are sessile organisms. This intriguing nature provokes the question of how they survive despite the continual perturbations caused by their constantly changing environment. The large amount of knowledge accumulated to date demonstrates the fascinating dynamic and plastic mechanisms, which underpin the diverse strategies selected in plants in response to the fluctuating environment. This phenotypic plasticity requires an efficient integration of external cues to their growth and developmental programs that can only be achieved through the dynamic and interactive coordination of various signaling networks. Given the versatility of intrinsic structural disorder within proteins, this feature appears as one of the leading characters of such complex functional circuits, critical for plant adaptation and survival in their wild habitats. In this review, we present information of those intrinsically disordered proteins (IDPs) from plants for which their high level of predicted structural disorder has been correlated with a particular function, or where there is experimental evidence linking this structural feature with its protein function. Using examples of plant IDPs involved in the control of cell cycle, metabolism, hormonal signaling and regulation of gene expression, development and responses to stress, we demonstrate the critical importance of IDPs throughout the life of the plant

Density functional study of Aun_n (n=2-20) clusters: lowest-energy structures and electronic properties

We have investigated the lowest-energy structures and electronic properties of the Au$_n$(n=2-20) clusters based on density functional theory (DFT) with local density approximation. The small Au$_n$ clusters adopt planar structures up to n=6. Tabular cage structures are preferred in the range of n=10-14 and a structural transition from tabular cage-like structure to compact near-spherical structure is found around n=15. The most stable configurations obtained for Au$_{13}$ and Au$_{19}$ clusters are amorphous instead of icosahedral or fcc-like, while the electronic density of states sensitively depend on the cluster geometry. Dramatic odd-even alternative behaviors are obtained in the relative stability, HOMO-LUMO gaps and ionization potentials of gold clusters. The size evolution of electronic properties is discussed and the theoretical ionization potentials of Au$_n$ clusters compare well with experiments.Comment: 6 pages, 7 figure

Pre-M Phase-promoting Factor Associates with Annulate Lamellae in Xenopus Oocytes and Egg Extracts

We have used complementary biochemical and in vivo approaches to study the compartmentalization of M phase-promoting factor (MPF) in prophase Xenopus eggs and oocytes. We first examined the distribution of MPF (Cdc2/CyclinB2) and membranous organelles in high-speed extracts of Xenopus eggs made during mitotic prophase. These extracts were found to lack mitochondria, Golgi membranes, and most endoplasmic reticulum (ER) but to contain the bulk of the pre-MPF pool. This pre-MPF could be pelleted by further centrifugation along with components necessary to activate it. On activation, Cdc2/CyclinB2 moved into the soluble fraction. Electron microscopy and Western blot analysis showed that the pre-MPF pellet contained a specific ER subdomain comprising "annulate lamellae" (AL): stacked ER membranes highly enriched in nuclear pores. Colocalization of pre-MPF with AL was demonstrated by anti-CyclinB2 immunofluorescence in prophase oocytes, in which AL are positioned close to the vegetal surface. Green fluorescent protein-CyclinB2 expressed in oocytes also localized at AL. These data suggest that inactive MPF associates with nuclear envelope components just before activation. This association may explain why nuclei and centrosomes stimulate MPF activation and provide a mechanism for targeting of MPF to some of its key substrates

Identification of New Wheat Genes for Durable Resistance of Adult Plants to Yellow Rust (Puccinia striiformis Westend. f. sp. Ericks)

Yellow rust is a wheat disease caused by Puccinia striiformis, this pathogen causes economic losses in susceptible materials, which represent up to 70% of wheat varieties. Currently, the incorporation of genetic resistance through molecular tools, is a process used in the generation of new varieties resistant to this pathogen. A strategy employed to identify genes involved in the resistance to yellow rust is to screen differential EST obtained by suppressive subtractive hybridization. In this research, cDNA was extracted from healthy and inoculated plants from the resistant line V-26 from INIFAP. A set of 200 differentially expressed EST were cloned and sequenced, and 31 of them were selected for expression profile analysis by RT-PCR; additionally, with the aim of validate RT-PCR results, five genes were selected for RT-qPCR analysis in genotypes inoculated by P. striiformis. The results showed high levels of expression of selected genes in genotypes classified as resistant in the field conditions (21, 143, 230, 242, 261 and 277), while in the susceptible genotype 16, few genes were induced by the rust. Expression profiles confirmed significant differences between resistant and susceptible lines