150 research outputs found

    Ostensive signals: markers of communicative relevance of gesture during demonstration to adults and children

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    Speakers adapt their speech and gestures in various ways for their audience. We investigated further whether they use ostensive signals (eye gaze, ostensive speech (e.g. like this, this) or a combination of both) in relation to their gestures when talking to different addressees, i.e., to another adult or a child in a multimodal demonstration task. While adults used more eye gaze towards their gestures with other adults than with children, they were more likely to use combined ostensive signals for children than for adults. Thus speakers mark the communicative relevance of their gestures with different types of ostensive signals and by taking different types of addressees into account

    Speaking and gesturing guide event perception during message conceptualization: Evidence from eye movements

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    Speakers’ visual attention to events is guided by linguistic conceptualization of information in spoken language production and in language-specific ways. Does production of language-specific co-speech gestures further guide speakers’ visual attention during message preparation? Here, we examine the link between visual attention and multimodal event descriptions in Turkish. Turkish is a verb-framed language where speakers’ speech and gesture show language specificity with path of motion mostly expressed within the main verb accompanied by path gestures. Turkish-speaking adults viewed motion events while their eye movements were recorded during non- linguistic (viewing-only) and linguistic (viewing-before-describing) tasks. The relative attention allocated to path over manner was higher in the linguistic task compared to the non-linguistic task. Furthermore, the relative attention allocated to path over manner within the linguistic task was higher when speakers (a) encoded path in the main verb versus outside the verb and (b) used additional path gestures accompanying speech versus not. Results strongly suggest that speakers’ visual attention is guided by language-specific event encoding not only in speech but also in gesture. This provides evidence consistent with models that propose integration of speech and gesture at the conceptualization level of language production and suggests that the links between the eye and the mouth may be extended to the eye and the hand

    A color and shape based algorithm for segmentation of white blood cells in peripheral blood and bone marrow images

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    Cataloged from PDF version of article.Computer-based imaging systems are becoming important tools for quantitative assessment of peripheral blood and bone marrow samples to help experts diagnose blood disorders such as acute leukemia. These systems generally initiate a segmentation stage where white blood cells are separated from the background and other nonsalient objects. As the success of such imaging systems mainly depends on the accuracy of this stage, studies attach great importance for developing accurate segmentation algorithms. Although previous studies give promising results for segmentation of sparsely distributed normal white blood cells, only a few of them focus on segmenting touching and overlapping cell clusters, which is usually the case when leukemic cells are present. In this article, we present a new algorithm for segmentation of both normal and leukemic cells in peripheral blood and bone marrow images. In this algorithm, we propose to model color and shape characteristics of white blood cells by defining two transformations and introduce an efficient use of these transformations in a marker-controlled watershed algorithm. Particularly, these domain specific characteristics are used to identify markers and define the marking function of the watershed algorithm as well as to eliminate false white blood cells in a postprocessing step. Working on 650 white blood cells in peripheral blood and bone marrow images, our experiments reveal that the proposed algorithm improves the segmentation performance compared with its counterparts, leading to high accuracies for both sparsely distributed normal white blood cells and dense leukemic cell clusters. (C) 2014 International Society for Advancement of Cytometr

    Speaking but not gesturing predicts event memory: A cross-linguistic comparison

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    Every day people see, describe, and remember motion events. However, the relation between multimodal encoding of motion events in speech and gesture, and memory is not yet fully understood. Moreover, whether language typology modulates this relation remains to be tested. This study investigates whether the type of motion event information (path or manner) mentioned in speech and gesture predicts which information is remembered and whether this varies across speakers of typologically different languages. Dutch- and Turkish-speakers watched and described motion events and completed a surprise recognition memory task. For both Dutch- and Turkish-speakers, manner memory was at chance level. Participants who mentioned path in speech during encoding were more accurate at detecting changes to the path in the memory task. The relation between mentioning path in speech and path memory did not vary cross-linguistically. Finally, the co-speech gesture did not predict memory above mentioning path in speech. These findings suggest that how speakers describe a motion event in speech is more important than the typology of the speakers’ native language in predicting motion event memory. The motion event videos are available for download for future research at https://osf.io/p8cas/

    Late sign language exposure does not modulate the relation between spatial language and spatial memory in deaf children and adults

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    Prior work with hearing children acquiring a spoken language as their first language shows that spatial language and cognition are related systems and spatial language use predicts spatial memory. Here, we further investigate the extent of this relationship in signing deaf children and adults and ask if late sign language exposure, as well as the frequency and the type of spatial language use that might be affected by late exposure, modulate subsequent memory for spatial relations. To do so, we compared spatial language and memory of 8-year-old late-signing children (after 2 years of exposure to a sign language at the school for the deaf) and late-signing adults to their native-signing counterparts. We elicited picture descriptions of Left-Right relations in Turkish Sign Language (TĂŒrk İƟaret Dili) and measured the subsequent recognition memory accuracy of the described pictures. Results showed that late-signing adults and children were similar to their native-signing counterparts in how often they encoded the spatial relation. However, late-signing adults but not children differed from their native-signing counterparts in the type of spatial language they used. However, neither late sign language exposure nor the frequency and type of spatial language use modulated spatial memory accuracy. Therefore, even though late language exposure seems to influence the type of spatial language use, this does not predict subsequent memory for spatial relations. We discuss the implications of these findings based on the theories concerning the correspondence between spatial language and cognition as related or rather independent systems

    Sensory modality of input influences encoding of motion events in speech but not co-speech gestures

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    Visual and auditory channels have different affordances and this is mirrored in what information is available for linguistic encoding. The visual channel has high spatial acuity, whereas the auditory channel has better temporal acuity. These differences may lead to different conceptualizations of events and affect multimodal language production. Previous studies of motion events typically present visual input to elicit speech and gesture. The present study compared events presented as audio- only, visual-only, or multimodal (visual+audio) input and assessed speech and co-speech gesture for path and manner of motion in Turkish. Speakers with audio-only input mentioned path more and manner less in verbal descriptions, compared to speakers who had visual input. There was no difference in the type or frequency of gestures across conditions, and gestures were dominated by path-only gestures. This suggests that input modality influences speakers’ encoding of path and manner of motion events in speech, but not in co-speech gestures

    Word order preference in sign influences speech in hearing bimodal bilinguals but not vice versa: Evidence from behavior and eye-gaze

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    We investigated cross-modal influences between speech and sign in hearing bimodal bilin- guals, proficient in a spoken and a sign language, and its consequences on visual attention during message preparation using eye-tracking. We focused on spatial expressions in which sign languages, unlike spoken languages, have a modality-driven preference to mention grounds (big objects) prior to figures (smaller objects). We compared hearing bimodal bilin- guals’ spatial expressions and visual attention in Dutch and Dutch Sign Language (N = 18) to those of their hearing non-signing (N = 20) and deaf signing peers (N = 18). In speech, hear- ing bimodal bilinguals expressed more ground-first descriptions and fixated grounds more than hearing non-signers, showing influence from sign. In sign, they used as many ground-first descriptions as deaf signers and fixated grounds equally often, demonstrating no influence from speech. Cross-linguistic influence of word order preference and visual attention in hearing bimodal bilinguals appears to be one-directional modulated by modality-driven difference

    Comparison of active vs. expectant management of the third stage of labor in women with low risk of postpartum hemorrhage: a randomized controlled trial

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    Objectives: To compare the ‘strictly’ active management protocol in women with low risk of postpartum hemorrhage using the expectant management protocol with respect to changes in hematologic parameters, uterotonics, blood transfusions, or additional interventions. Material and methods: A randomized controlled prospective trial in which 934 singleton parturients enrolled; 654 were randomly assigned to the active and mixed management groups. The primary outcome parameter was the reduction in hemoglobin concentrations due to delivery, and the secondary outcome parameters were changes in hemoglobin of more than 3 g/dL (ΔHb ≄ 3 g/dL), durations of the third stage of labor, need for additional uterotonic agents, blood transfusions, manual removal of the placenta, and surgical evacuation of retained products of conception. Results: The mean postpartum hemoglobin concentration was significantly higher (P = 0.04) in the active management group with a significantly lower reduction (P = 0.03). Falls of hemoglobin levels of more than 3 g/dL (ΔHb ≄ 3g/dL) were less common in the active management group though not significantly (P = 0.32). The mean duration of the third stage of labor was significantly (P < 0.001) shorter in the active management group. There was no significant difference between the two groups with regard to the need for additional uterotonic agents, uterine atony, blood transfusion, manual removal of the placenta, surgical evacuation of retained products of conception, and prolonged third stage of labor. Conclusions: Although active management of the third stage of labor was associated with higher postpartum hemoglobin levels, it did not influence the risk of ‘severe postpartum hemorrhage’ in women with low risk of postpartum hemorrhage

    Neurobrucellosis with transient ischemic attack, vasculopathic changes, intracerebral granulomas and basal ganglia infarction: a case report

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    <p>Abstract</p> <p>Introduction</p> <p>Central nervous system involvement is a rare but serious manifestation of brucellosis. We present an unusual case of neurobrucellosis with transient ischemic attack, intracerebral vasculopathy granulomas, seizures, and paralysis of sixth and seventh cranial nerves.</p> <p>Case presentation</p> <p>A 17-year-old Caucasian man presented with nausea and vomiting, headache, double vision and he gave a history of weakness in the left arm, speech disturbance and imbalance. Physical examination revealed fever, doubtful neck stiffness and left abducens nerve paralysis. An analysis of his cerebrospinal fluid showed a pleocytosis (lymphocytes, 90%), high protein and low glucose levels. He developed generalized tonic-clonic seizures, facial paralysis and left hemiparesis. Cranial magnetic resonance imaging demonstrated intracerebral vasculitis, basal ganglia infarction and granulomas, mimicking the central nervous system involvement of tuberculosis. On the 31st day of his admission, neurobrucellosis was diagnosed with immunoglobulin M and immunoglobulin G positivity by standard tube agglutination test and enzyme-linked immunosorbent assay in both serum and cerebrospinal fluid samples (the tests had been negative until that day). He was treated successfully with trimethoprim and sulfamethoxazole, doxycyline and rifampicin for six months.</p> <p>Conclusions</p> <p>Our patient illustrates the importance of suspecting brucellosis as a cause of meningoencephalitis, even if cultures and serological tests are negative at the beginning of the disease. As a result, in patients who have a history of residence or travel to endemic areas, neurobrucellosis should be considered in the differential diagnosis of any neurologic symptoms. If initial tests fail, repetition of these tests at appropriate intervals along with complementary investigations are indicated.</p
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