19 research outputs found

    Oedema associated with risperidone - A case report and literature review

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    WOS: 000176267000011

    Clozapine and suicide

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    Suicidal ideation, suicide plans, attempted and completed suicide cc cur frequently in patients with schizophrenia. About 50 percent of all schizophrenic patients attempt suicide, and 10 to 15 percent of them die because of suicide. Suicide risk has been reported to be high especially for treatment-resistant and treatment-intolerant cases. Clozapine is a novel antipsychotic drug in the treatment of schizophrenic patients who are resistant or intolerant to conventional antipsychotics. Clozapine is found to cause decreased suicidality in high risk patients like antipsychotic resistant or intolerant patients. In this case report, we presented a schizophrenic patient who committed suicide during clozapine treatment and discussed the notion of reduced suicidality in schizophrenic patients with clozapine treatment in the light of literature and this case

    Interferon alpha 2a in discoid lupus erythematosus

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    Discoid lupus erythematosus (DLE) is an autoimmune, chronic skin disease. It may lead to cosmetic unacceptable scars on the face and when it is localized on the scalp, it may lead to permanent cicatricial alopecia. In various publications, interferon (IFN) alpha was found to be efficient in autoimmune disease such as multiple sclerosis, arthritis rheumatica and thrombocytopenic purpura. This study has been done to investigate the therapeutic effect of IFN alpha 2a in DLE. Six patients were studied. These subjects were diagnosed as DLE by clinical and histopathological data. Patients who have not been treated by any systemic and topical treatment for DLE within the last month, were included. 18-27 millions IU of IFN alpha 2a per week was administered under hospital conditions for four weeks. The influenza-like symptoms, occurring during daily treatment of 3-4.5 millions IU IFN alpha 2a were treated by paracetamol. The fading of the erythema and the reduction of the diameter were used as healing criteria. So, 50% healing in three cases and 70% in two cases, were observed while in the remaining one case the healing rate was under 50%. Our data support that IFN alpha 2a is a potential agent either for curative or adjunct treatment of DLE

    Comorbidity in obsessive-compulsive disorder

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    WOS: 000178905000584

    The relationship between suicidal behaviour and symptomatology among patients with schizophrenia

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    18th ECNP Congress 2005 -- OCT 22-26, 2005 -- Amsterdam, NETHERLANDSWOS: 000233860601035…ECN

    Association between idiopathic mitral valve prolapse and panic disorder

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    PubMedID: 11063765Aim. To evaluate the association between idiopathic mitral valve prolapse and panic disorder. Methods. The study comprised 50 patients with idiopathic mitral valve prolapse, 50 patients with panic disorder, and 50 healthy controls. All subjects underwent echocardiographic evaluation. If idiopathic mitral valve prolapse was present, the level of prolapse was measured. To reach psychiatric diagnosis, the Structured Clinical Interview for DSM-IV Axis I Disorders, clinician version, was administered to all subjects. For psychometric evaluation, all subjects completed the Symptom Check List, Beck Depression Inventory, and State and Trait Anxiety Inventory. Results. The prevalence of panic disorder was 16% in patients with idiopathic mitral valve prolapse, and 2% in healthy controls (p=0.03). The average scores on all psychometric scales were the highest in the panic disorder group, whereas average scores in idiopathic mitral valve prolapse group were significantly higher than in the control group (p<0.001). Idiopathic mitral valve prolapse and panic disorder groups displayed similar features of panic attack symptoms. Panic disorder cases with idiopathic mitral valve prolapse and those without it did not significantly differ in terms of psychometric evaluations and clinical symptoms. Conclusion. The possibility of comorbidity of panic disorder and idiopathic mitral valve prolapse should be taken into account in the approach to the patients diagnosed with either of the disorders

    Thyroid functions in lithium-treated patients

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    WOS: 000178905000754

    Efficiency of long term prophylactic treatment in bipolar disorder

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    5th Biennial Conference of the International-Society-for-Bipolar-Disorders -- MAR 14-17, 2012 -- Istanbul, TURKEYWOS: 000301531000273…Int Soc Bipolar Disorder
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