Clozapine and suicide

Abstract

Suicidal ideation, suicide plans, attempted and completed suicide cc cur frequently in patients with schizophrenia. About 50 percent of all schizophrenic patients attempt suicide, and 10 to 15 percent of them die because of suicide. Suicide risk has been reported to be high especially for treatment-resistant and treatment-intolerant cases. Clozapine is a novel antipsychotic drug in the treatment of schizophrenic patients who are resistant or intolerant to conventional antipsychotics. Clozapine is found to cause decreased suicidality in high risk patients like antipsychotic resistant or intolerant patients. In this case report, we presented a schizophrenic patient who committed suicide during clozapine treatment and discussed the notion of reduced suicidality in schizophrenic patients with clozapine treatment in the light of literature and this case

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