Sensing, measuring and modelling the mechanical properties of sandstone

We present a hybrid framework for simulating the strength and dilation characteristics of sandstone. Where possible, the grain-scale properties of sandstone are evaluated experimentally in detail. Also, using photo-stress analysis, we sense the deviator stress (/strain) distribution at the microscale and its components along the orthogonal directions on the surface of a V-notch sandstone sample under mechanical loading. Based on this measurement and applying a grain-scale model, the optical anisotropy index K0 is inferred at the grain scale. This correlated well with the grain contact stiffness ratio K evaluated using ultrasound sensors independently. Thereafter, in addition to other experimentally characterised structural and grain-scale properties of sandstone, K is fed as an input into the discrete element modelling of fracture strength and dilation of the sandstone samples. Physical bulk scale experiments are also conducted to evaluate the load-displacement relation, dilation and bulk fracture strength characteristics of sandstone samples under compression and shear. A good level of agreement is obtained between the results of the simulations and experiments. The current generic framework could be applied to understand the internal and bulk mechanical properties of such complex opaque and heterogeneous materials more realistically in future

Effectiveness and safety of alternate-day simvastatin and fenofibrate on mixed hyperlipidemia

WOS: 000079360100030PubMed ID: 10190536This randomized prospective clinical study evaluated the lipid-lowering effects and safety of a new combination regimen in patients with mixed hyperlipidemia. The data show that alternate-day simvastatin and fenofibrate therapy was as effective as the standard daily combination of the same drugs at the same doses, and it was safer, less expensive, and more tolerable

E-page Original Images. Left pulmonary artery thrombosis diagnosed by transesophageal echocardiography.

PubMed ID: 18400622[No abstract available

Left atrial phasic functions and plasma NT-proBNP levels predict atrial fibrillation development in patients with hypertrophic cardiomyopathy: A prospective follow-up study

Annual Meeting of the European-Society-of-Cardiology (ESC) -- AUG 30-SEP 03, 2014 -- Barcelona, SPAINWOS: 000343001306565European Soc Cardio

Mycotic aneurysms of aortic root and aorta-to-left atrial fistula complicating bicuspid aortic valve endocarditis

WOS: 000235208900008PubMed ID: 16357480Unlike root abscess, fistula formation is quite uncommon in aortic valve endocarditis. In this report, we describe a patient with subacute bicuspid aortic valve endocarditis complicated by aortic insufficiency, mycotic aneurysms of the aortic root and fistulous communication between the aorta and the left atrium and his recovery upon surgical treatment. Copyright (c) 2006 S. Karger AG, Basel

Blood nitrate levels in hypertensive diabetic patients and relationship with endothelial dysfunction

15th European Meeting on Hypertension -- JUN 17-21, 2005 -- Milan, ITALYWOS: 000230639802454European Soc Hypertens, AstraZeneca, Bristol-Myers Squibb Co, Boehringer Ingelheim, MSD, NOVARTIS, RECORDATI, SANKYO, Sanofi Aventis, Bayer Healthcare AG, Pfizer Inc, Solvay Pharmaceut Gmb