PHYSICAL, CHEMICAL AND TECHNOLOGICAL FEATURES OF SOME POTATOES KINDS GROWN IN HATAY PROVINCE OF TURKEY

In this research which aimed to determine of physical, chemical and tecnological features of some kinds of potatoes which are grown in Hatay, the exams of Agria, Alaska, Anais, Buchan, Daline, Eladie, Goliat, Harmony, Justine, Lilla, Marabel, Mortana, Safrane, Sebastian, Surde, Szazbouzcp, VanGogh and White Lady as material worked to fresh potatoes, chips and finger potatoes are used. The direction of the knowledge has been obtained Agria, Anais, Alaska, Daline, Harmony, Justine, Safrane, Mortana, Van Gogh and White Lady potatoes variaties are appropriate for potatoes chips process, because of high dry substance rate and low reduced sugar rate. It is determined that the products produced with high dry substance rate potatoes have much more quality and fried products absorb less oil. Sebastian, Szazbouzcp, Goliat and Buchan potatoes varieties are suitable for finger potatoes process. Eladie, Anais, Mortana and Daline are appropiate for boiling process. Because these kinds of potatoes have low dry substance rate. Consequently their absorption rate is high. Van Gogh, Surde, Szazbouzcp, Alaska, Agria and Eladie are suitable for starch production, because of high starch they have. Because it is fixed that starch rates are higher than the others. At the fresh lump, chips and finger potatoes some physical and chemical analysis had been practiced. Obtained results; it had been seen that the kinds of Anais, Buchan, Daline, Szazbouzcp, Surde and Mortana is not suitable for been worked to chips and finger potatoes. The other kinds had been seen suitable for been worked to chips and finger potatoes

Species diversity and distribution of ruderal flora on landfills in Maradi city, Niger

Waste management continues to be a critical environmental issue in cities. It impacts on the well being of the population, the environment and the biodiversity. In the city of Maradi, in Niger, more interest is given to the problem in order to understand the whole waste management system. It is in this context that this study is carried out to investigate on the role of ruderal flora on the municipal solid wastes dumpsites and landfill sites in Maradi city. The specific objectives are to determine the floristic diversity and distribution of ruderal flora on the municipal solid waste disposal sites, and to identify potential species that can play an important role in the phytoremediation of these sites. In total, 65 species belonging to 52 genera and 24 families were recorded. These species can be categorised into two groups containing anthropic and nitrophilic species according to the ascending Hierarchical Classification (AHC) at 25% similarity. Characteristic species of the first group G1 are Amaranthus viridis and Cucurbita pepo, and Datura innoxia and Cucumis melo for the second group G2. Other ruderal species, namely Amaranthus spinosus L., Amaranthus viridis L., Celosia trygina L., Datura innoxia Mill., and an introduced woody species, Cuphea hyssopifolia Kunth., found are not included in the Maradi city list of species. Datura innoxia, Amaranthus viridis and Amaranthus spinosus are species known to tolerate different degrees of pollution and their ecology should be further study to better understand how they can be used for phytoremediation on this kind of sites

Thermodynamics of Decaying Vacuum Cosmologies

The thermodynamic behavior of vacuum decaying cosmologies is investigated within a manifestly covariant formulation. Such a process corresponds to a continuous irreversible energy flow from the vacuum component to the created matter constituents. It is shown that if the specific entropy per particle remains constant during the process, the equilibrium relations are preserved. In particular, if the vacuum decays into photons, the energy density $\rho$ and average number density of photons $n$ scale with the temperature as $\rho \sim T^{4}$ and $n \sim T^{3}$. The temperature law is determined and a generalized Planckian type form of the spectrum, which is preserved in the course of the evolution, is also proposed. Some consequences of these results for decaying vacuum FRW type cosmologies as well as for models with ``adiabatic'' photon creation are discussed.Comment: 21 pages, uses LATE

Resistance Mechanisms for the Bruton\u27s Tyrosine Kinase Inhibitor Ibrutinib

BACKGROUND Ibrutinib is an irreversible inhibitor of Bruton\u27s tyrosine kinase (BTK) and is effective in chronic lymphocytic leukemia (CLL). Resistance to irreversible kinase inhibitors and resistance associated with BTK inhibition have not been characterized. Although only a small proportion of patients have had a relapse during ibrutinib therapy, an understanding of resistance mechanisms is important. We evaluated patients with relapsed disease to identify mutations that may mediate ibrutinib resistance. METHODS We performed whole-exome sequencing at baseline and the time of relapse on samples from six patients with acquired resistance to ibrutinib therapy. We then performed functional analysis of identified mutations. In addition, we performed Ion Torrent sequencing for identified resistance mutations on samples from nine patients with prolonged lymphocytosis. RESULTS We identified a cysteine-to-serine mutation in BTK at the binding site of ibrutinib in five patients and identified three distinct mutations in PLC gamma 2 in two patients. Functional analysis showed that the C481S mutation of BTK results in a protein that is only reversibly inhibited by ibrutinib. The R665W and L845F mutations in PLC gamma 2 are both potentially gain-of-function mutations that lead to autonomous B-cell-receptor activity. These mutations were not found in any of the patients with prolonged lymphocytosis who were taking ibrutinib. CONCLUSIONS Resistance to the irreversible BTK inhibitor ibrutinib often involves mutation of a cysteine residue where ibrutinib binding occurs. This finding, combined with two additional mutations in PLC gamma 2 that are immediately downstream of BTK, underscores the importance of the B-cell-receptor pathway in the mechanism of action of ibrutinib in CLL

New Fisheries-related data from the Mediterranean Sea (April 2015)

In this second Collective Article with fisheries-related data from the Mediterranean Sea we present the evaluation of bony structures in aging of Barbus tauricus, otolith dimensions-body length relationships for two species (Trachinus draco and Synchiropus phaeton), information on the growth of juvenile Thunnus thynnus and of Ruvettus pretiosus, weight-length relationships for three species (Aulopus fiamentosus, Thunnus thynnus and Tylosurus acus imperialis) and data on feeding habits and reproduction of Aulopus fiamentosus

Prognostic and Biologic Relevance of Clinically Applicable Long Noncoding RNA Profiling in Older Patients with Cytogenetically Normal Acute Myeloid Leukemia

We have previously shown that expression levels of 48 long noncoding RNAs (lncRNA) can generate a prognostic lncRNA score that independently associates with outcome of older patients with cytogenetically normal acute myeloid leukemia (CN-AML). However, the techniques used to identify and measure prognostic lncRNAs (i.e., RNA sequencing and microarrays) are not tailored for clinical testing. Herein, we report on an assay (based on the nCounter platform) that is designed to produce targeted measurements of prognostic lncRNAs in a clinically applicable manner. We analyzed a new cohort of 76 older patients with CN-AML and found that the nCounter assay yielded reproducible measurements and that the lncRNA score retained its prognostic value; patients with high lncRNA scores had lower complete remission (CR) rates (P = 0.009; 58% vs. 87%), shorter disease-free (P = 0.05; 3-year rates: 0% vs. 21%), overall (OS; P = 0.02, 3-year rates: 10% vs. 29%), and event-free survival (EFS; P = 0.002, 3-year rates: 0% vs. 18%) than patients with low lncRNA scores. In multivariable analyses, the lncRNA score independently associated with CR rates (P = 0.02), OS (P = 0.02), and EFS (P = 0.02). To gain biological insights, we examined our initial cohort of 71 older patients with CN-AML, previously analyzed with RNA sequencing. Genes involved in immune response and B-cell receptor signaling were enriched in patients with high lncRNA scores. We conclude that clinically applicable lncRNA profiling is feasible and potentially useful for risk stratification of older patients with CN-AML. Furthermore, we identify potentially targetable molecular pathways that are active in the high-risk patients with high lncRNA scores

Beta, Dipole and Noncommutative Deformations of M-theory Backgrounds with One or More Parameters

We construct new M-theory solutions starting from those that contain 5 U(1) isometries. We do this by reducing along one of the 5-torus directions, then T-dualizing via the action of an O(4,4) matrix and lifting back to 11-dimensions. The particular T-duality transformation is a sequence of O(2,2) transformations embedded in O(4,4), where the action of each O(2,2) gives a Lunin-Maldacena deformation in 10-dimensions. We find general formulas for the metric and 4-form field of single and multiparameter deformed solutions, when the 4-form of the initial 11-dimensional background has at most one leg along the 5-torus. All the deformation terms in the new solutions are given in terms of subdeterminants of a 5x5 matrix, which represents the metric on the 5-torus. We apply these results to several M-theory backgrounds of the type AdS_r x X^{11-r}. By appropriate choices of the T-duality and reduction directions we obtain analogues of beta, dipole and noncommutative deformations. We also provide formulas for backgrounds with only 3 or 4 U(1) isometries and study a case, for which our assumption for the 4-form field is violated.Comment: v2:minor corrections, v3:small improvements, v4:conclusions expanded, to appear in Class. Quant. Gra

Higher spin fields and the problem of cosmological constant

The cosmological evolution of free massless vector or tensor (but not gauge) fields minimally coupled to gravity is analyzed. It is shown that there are some unstable solutions for these fields in De Sitter background. The back reaction of the energy-momentum tensor of such solutions to the original cosmological constant exactly cancels the latter and the expansion regime changes from the exponential to the power law one. In contrast to the adjustment mechanism realized by a scalar field the gravitational coupling constant in this model is time-independent and the resulting cosmology may resemble the realistic one.Comment: 15 pages, Latex twic