A thoracic-epidural granulocytic sarcoma case that was diagnosed preceding the onset of and that recurred co-incidental to acute promyelocytic leukemia, which developed after surgical treatment.

Granulocytic sarcoma or chloroma is a tumor seen in myelocytic leukemia. Spinal epidural onset is rare and is generally seen before or together with the onset of myelocytic leukemia. An epidural mass located at the 2nd-5th thoracic levels in an 18-year-old male patient was pathologically diagnosed as granulocytic sarcoma. Radiotherapy was performed after surgical intervention. Ten months later, he was re-admitted with abdominal pain. At this time, an epidural mass at the 6th-9th thoracic levels was detected on magnetic resonance imaging, and acute promyelocytic leukemia was diagnosed. After systemic chemotherapy, partial remission was achieved. We aimed to present this rare case with its remarkable follow-up findings.</p

Miscellaneous neuromuscular symptoms and signs in long Covid

We have completed the 3rd year of the Covid-19 pandemic. In the early stages of the disease, we were faced with a wide variety of symptoms and signs, including the neuromuscular system, as well as life-threatening cardiopulmonary, neurovascular and immun complications. In our study, we questioned fatigue, myalgia, arthralgia, dyspnea, headache, dizziness, neck pain, back pain, low back pain, knee-hip-foot joint pain, vascular claudication (lower extremity pain/cramp), neuropathic pain, morning stiffness, joint swelling, pernio, imbalance in walking in patients (N=111; 65 female, 29 male) aged 20-59 years, who applied to our outpatient clinic in the last 1 year and had Covid-19. The mean time after Covid-19 was 5.8 ±2.1 months. The duration of Covid-19 treatment was a minimum of 5 days and a maximum of 12 days (median=5 days). Weight loss in 14.4% (median=3.5 kg), anorexia 17.1%, myalgia 41.4% (visual analog scale, VAS=5.1±1.9 cm), arthralgia 24.3% (VAS=5.1±2 cm), fatigue 63.1%, joint swelling 1.8%, pernio sign 0.9%, morning stiffness 7.2% (median=15 min, min 5-maximum 60 min), headache 39.6%, neuropathic pain 15.3%, effort dyspnea 38.7%, 30 second chair stand test= 14.9 ±3.6, vascular claudication symptom 11.7%, neck pain 27.0%, low back pain 30.6%, back pain 36%, hip-knee-foot pain 18.0%, gait imbalance 1.8%, dizziness 18.9% were observed. While fatigue (p=0.05), headache (p=0.04), and dyspnea (p=0.021) complaints were higher in males; VAS (arthralgia) was found higher in females (p=0.026). In the post-Covid-19 period, we see many neuromuscular symptoms and signs, especially fatigue, myalgia, headache and back pain. In addition, lower extremity vascular claudication and neuropathic pain related with chronic pain should not be overlooked in these patients. [Med-Science 2023; 12(1.000): 238-43

LONG-TERM STORAGE OF A NUMBER OF MICROORGANISM SPECIES USING DIFFERENT CRYOPROTECTANTS

WOS: 000437783100057This study aims to generate a microalgae culture collection, and ensure the long-term survival of this collection by prolonging the period when the isolated microalgae and other microorganism cultures can be preserved. The microalgae cultures included four microalgae species (Chlorella vulgaris Beyerinck [Beij erinck], Klebsormidium subtile (Kutzing) Mikhailyuk, Glaser, Holzinger & Karsten, Microcoleus autumnalis (Gomont) Strunecky, Komarek & J.R. Johansen and Synechococcus bigranulatus Skuja), two bacteria species (Staphylococcus aureus and Escherichia coli) and two fungi species (Aspergillus niger and Penicillium sp.). The study applied a cryopreservation protocol at -80 degrees C directly to each of the species. The cryoprotective agents used in the study were dimethyl sulfoxide (DMSO), glycerol and skimmed milk at a final concentration of 5% for the microalgae in addition to an application without any cryoprotectant at all. The cryoprotectant agents used for this procedure were 15% final glycerol concentration for the bacteria and 10% skimmed milk for the fungi. After six months, the strains of C. vulgaris (93%), S. bigranulatus (83%) and M autumnalis (80%) showed higher viability rates in glycerol, while the strain of K. subtile (93%) showed higher viability rates in skimmed milk. The recovery ratio of E. coli, S. aureus, A. niger and Penicillium sp. were found to be 5.10, 3.23, 1.98 and 2.67 log CFU/ml, respectively

Diversity and Ecology of Algae from Melen River (Western Black Sea River Catchment) in Turkey

WOS: 000432895600005Algae are among the key organisms of aquatic ecosystems. While there have been a large number of important algological studies on different river basins in Turkey, the use of algae in biomonitoring is a new approach. Epiphytic and epilithic algae in the Melen River were studied between May 2003 and April 2004. A total of 148 taxa, with 101 belonging to Bacillariophyta, 18 to Chlorophyta, 9 to Charophyta, 13 to Cyanobacteria, 5 to Euglenophyta, and 2 to Miozoa, were identified in this study. Members of Bacillariophyta were the dominant taxa at all sites, with oligohalobious-indifferents and alkaliphiles being the most common. Among the non-diatom taxa, there were more species with oligohalobious-indifferent and indifferent properties. The river water was alkaline and temperate, with low salinity characters. Bio-indications (autecology) of the river were studied. From the results, organic pollution indicators of Watanabe's classification (46 species, 31.1%) constituted three groups (saproxen, eurysaprobe and saprophile). Based on the classification (according to Watanabe's system) and RPI (River Polluted Index), the ecological conditions of Melen River were assessed as low, with a moderate level of organic pollution, and lightly to moderately polluted, respectively.Gazi University, Scientific Projects Research ManagementGazi UniversityWe would like to thank Gazi University, Scientific Projects Research Management for financing this research

HEAVY METAL BIOSORPTION OF COPPER IONS BY IMMOBILIZED BIOMASS OF STICHOCOCCUS SUBTILIS (KUTZING) KLERCKER

WOS: 000413499500011In this study, the ability of Stichococcus subtilis (Kiitzing) Klercker was used for heavy metal removal adsorbstion capacity. The sorption ability of S. subtilis was investigated using Cu metallic solutions. In the analysis, pH effect, equilibrium timing, initial metal ions concentration and temperature ranges were investigated. For single metal systems, sorption isotherms were well-fitted to the Langmuir model. The results of the maximum Cu biosorption capacities were found as 2.70 and 10.4 mg/g for alginate and alginate cells, with pH 5.5, corresponding to the initial Cu concentration of 50 mg/L. Cu biosorption on all the tested biosorbents agreed with Langmuir adsorption isotherm model

Calciphylaxis Involving Both the Upper and Lower Extremities

Calciphylaxis is an uncommon complication of end stage renal disease (ESRD) and secondary hyperparathyroidism. It characterized by cutaneous necrosis with mural calcifications and thrombosis in the small vessels of dermis. It is important to diagnose and treat, because of mortality rate from calciphylaxis is very high. We present the case of a patient with ESRD and type II diabetes mellitus developing calciphylaxis of the both upper and lower extremities had normal corrected calcium-phosphate product level. After amputation, necrosis was showed rapid progression resulting in death in one month

The Abundant and Wide-Spread Species of Algae in the Algal Flora of the Lower Euphrates Basin Wetlands

WOS: 000293210300008The research on the algae of the Lower Euphrates Basin of the South East Anatolian Region was done between November 2001 and August 2003 at twenty one stations each, on four different habitats (plankton, epipelon, epifithon, epilithon). Due to the density level of species, Cyanobacteria, Bacillariophyta and Chlorophycophyta were conspicous. A bloom of Microcystis aeruginosa was observed in Ataturk and Halfeti Reservoirs in September 2002. In the same period, Cyclotella ocellata, in May 2003 Cyclostephanos dubius, and in August the same year. It could be said that Ceratium hirundinella species were close to bloom level. High density diatoms were found more in plankton. Species such as Oscillatoria spp., Spirogyra spp. and Lyngbya spp. were observed to be more wide-spread than the others. Species such as Oscillatoria spp., Leiblenia epiphytica and Phormidium mucicola increased in abundance in February and September in running waters. Within these months, water temperature in the region ranged between 18-22 degrees C. According to some chemical and biological data, the basin was mesotrophic while some streams with sewage inputs, were observed to have eutrophic characteristics.TUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TBAG-2046 (101047)]The study was supported by TUBITAK Project No. TBAG-2046 (101047)

Enoxaparin-associated giant retroperitoneal hematoma in pulmonary embolism treatment

Context: Retroperitoneal hematoma may usually occur as a result of trauma. A life threatening retroperitoneal hematoma is not expected complication of anticoagulation treatment and rarely reported. Low molecular weight heparins (Enoxaparin) which are used as effective and safe medicine in the venous thromboemboly treatment have some major complications such as hematomas of different organs. We aim to present a giant spontaneous retroperitoneal hematoma after anticoagulant treatment of pulmonary embolism with enoxaparin. Case Report: A 73-year-old male patient with the diagnosis of pulmonary embolism underwent anticoagulant treatment (enoxaparin). In the second day of admission, the patient had an episode of abdominal and back pain. Abdominal ultrasonography and computerized tomographic scan revealed a giant retroperitoneal hematoma. Enoxaparin treatment was then stopped and the supportive treatment was started. In the following days, hemoglobin levels returned to normal and a control CT revealed regression of hematoma size. Conclusion: The anticoagulant treatment with enoxaparin may lead to severe hematomas. Therefore, the clinical suspicion is required especially in elderly patients and patients with impaired renal function for retroperitoneal hematoma, when they suffer from acute abdominal pain

Diversity and Ecology of Algae from Melen River (Western Black Sea River Catchment) in Turkey

Algae are among the key organisms of aquatic ecosystems. While there have been a large number of important algological studies on different river basins in Turkey, the use of algae in biomonitoring is a new approach. Epiphytic and epilithic algae in the Melen River were studied between May 2003 and April 2004. A total of 148 taxa, with 101 belonging to Bacillariophyta, 18 to Chlorophyta, 9 to Charophyta, 13 to Cyanobacteria, 5 to Euglenophyta, and 2 to Miozoa, were identified in this study. Members of Bacillariophyta were the dominant taxa at all sites, with oligohalobious-indifferents and alkaliphiles being the most common. Among the non-diatom taxa, there were more species with oligohalobious-indifferent and indifferent properties. The river water was alkaline and temperate, with low salinity characters. Bio-indications (autecology) of the river were studied. From the results, organic pollution indicators of Watanabe's classification (46 species, 31.1\%) constituted three groups (saproxen, eurysaprobe and saprophile). Based on the classification (according to Watanabe's system) and RPI (River Polluted Index), the ecological conditions of Melen River were assessed as low, with a moderate level of organic pollution, and lightly to moderately polluted, respectively