PREVALENCE AND ANTIBIOTICS SUSCEPTIBILITY PROFILEOF Listeria monocytogenes ISOLATED FROM PROCESSED ANDUNPROCESSED MEAT PRODUCTS

The antibiotics susceptibility pattern of Listeria monocytogenes isolated from processed and unprocessed meats were investigated. Isolation of Listeria monocytogenes was done using the FDA BAM method. A total of fifty (50) retail meat samples consisting of twenty (20) raw meats, 15 fresh processed meat samples and 15 processed ready-to-eat samples were analyzed on Listeria Selective Agar and Listeria Chromogenic Agar following pre-enrichment. Isolates were screened for thei

PREVALENCE OF MULTIPLE ANTIBIOTIC RESISTANCE AMONGBACTERIA ISOLATED FROM WASTEWATER OF HOME-SITEDAQUACULTURE IN OGUN STATE, SOUTH-WESTERN NIGERIA

 This study investigated the prevalence of multiple antibiotic resistant bacteria in wastewaters of sixaquaculture farms from Ijebu Ode, Ijebu Igbo and Ago Iwoye towns of Ogun State, South-western Nigeria

Clinical effects of Garcinia kola in knee osteoarthritis

<p>Abstract</p> <p>Objectives</p> <p>Over the past years, there has been a growing number of knee osteoarthritis (KOA) patients who are not willing to comply with long-term non-steroidal anti-inflammatory drugs (NSAID) treatment and wish to use herbal anti- rheumatic medicine. This study assessed the clinical effects of <it>Garcinia kola </it>(GK) in KOA patients.</p> <p>Patients and methods</p> <p>Prospective randomized, placebo controlled, double blind, clinical trial approved by the institutional medical ethics review board and written informed consent obtained from each patient. All KOA patients presenting at the Obafemi Awolowo University Teaching Hospital complex were recruited into the study. The patients were grouped into four (A = Placebo, B = Naproxen, C = <it>Garcinia kola</it>, D = Celebrex). The drugs and placebo were given twice a day per oral route. Each dose consisted of 200 mg of <it>G. kola</it>, Naproxen (500 mg), Celebrex (200 mg) and Ascorbic acid (100 mg). The primary outcome measure over six weeks study period was the change in mean WOMAC pain visual analogue scales (VAS). Secondary outcome measures included the mean change in joint stiffness and physical function (mobility/walking).</p> <p>Results</p> <p>143 patients were recruited, 84 (58.7%, males – 24, females – 60) satisfied the selection criteria and completed the study. The effect of knee osteoarthritis bilateralism among the subjects was not significant on their outcome (p > 0.05). The change in the mean WOMAC pain VAS after six weeks of <it>G. kola </it>was significantly reduced compared to the placebo (p < 0.001). Multiple comparisons of the mean VAS pain change of <it>G. kola </it>group was not lowered significantly against the naproxen and celebrex groups (p > 0.05). The onset of <it>G. kola </it>symptomatic pain relief was faster than the placebo (p < 0.001). However, it was slower than the active comparators (p > 0.05). The duration of therapeutic effect of <it>Garcinia kola </it>was longer than the placebo (p > 0.001). <it>G. kola </it>period of effect was less than naproxen and celebrex (p < 0.001). <it>G. kola </it>subjects had improved mean change mobility/walking after six weeks better than the control group(p < 0.001). The mean change in mobility of the <it>G. kola </it>group when compared to the active comparators was not significantly better (p < 0.05). The mean change of knee joint stiffness (p < 0.001) and the change of mean WOMAC score (p < 0.001) were improved on <it>Garcinia kola </it>as compared to the placebo. The mid term outcome of eleven <it>Garcinia kola </it>subjects after cessation of use had a mean pain relief period of 17.27 +/- 5.15 days (range: 9–26 days). There was no significant cardiovascular, renal or drug induced adverse reaction to <it>Garcinia kola</it>.</p> <p>Conclusion</p> <p><it>Garcinia kola </it>appeared to have clinically significant analgesic/anti-inflammatory effects in knee osteoarthritis patients. <it>Garcinia kola </it>is a potential osteoarthritis disease activity modifier with good mid term outcome. Further studies are required for standardization of dosages and to determine long-term effects.</p

Pharmacy Patrons \u27Awareness of Pharmacists\u27 Education and Routine Patient Care Responsibilities

Purpose: To assess the similarities between pharmacists’ and pharmacy patrons’ views of pharmacists’ roles and to explore the extent to which persons actually see pharmacists assuming certain roles. Method: Cross-sectional survey was administered to pharmacists and patients who were filling prescriptions or seeking nonprescription medications in 9 community pharmacies in Morgantown, West Virginia. The survey assessed 11 routine patient care services. Main outcome measures include opinions of pharmacists and patients about responsibility for providing 11 routine care services and the extent to which these services are provided. Results: Pharmacists and patients had similar opinions about services that pharmacists should provide for 7 of the 11 services evaluated. For the other 4 items for which opinions were divergent, the mean scores for the extent to which pharmacists provide these services indicated that pharmacists do not always provide these services. Conclusion: Pharmacy patrons might not attribute certain patient-related functions to pharmacists because pharmacists do not frequently perform these routine care-related services in actual practice. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page

LEVELS AND DRIVERS OF VULNERABILITY TO CLIMATE CHANGE BY IFAD-VCDP FARMERS IN NORTH CENTRAL NIGERIA

Although a number of studies have been carried out on climate change but the levels of vulnerability of farmers and factors affecting vulnerability of the farmers to this topical issue have not been sufficiently determined in the study area, giving rise to this study. The study was conducted in Benue and Niger States involving 483 IFAD-VCDP farmers. A total of 500 questionnaires were distributed, however only 96.6% were completed and returned. As such the data analysis was based on 483 farmers under International Fund for Agricultural Development (IFAD) – Value Chain Development Programme (VCDP) from 10 participating Local Government of the two States. Both primary and secondary data were utilized for this study. The primary data were collected via questionnaire administered by trained enumerators, while the secondary data were collected from Food and Agriculture Organization (FAO) and Nigerian Meteorological Agency (NIMET). The data were analysed using descriptive statistics, vulnerability index and Beta regression model. The farmers were aware of eighteen climate change variables with assorted levels of occurrences. There was moderate vulnerable to climate change in the study area necessitating the need of enhanced awareness and capacity building to upgrade their home-grown adaptation strategies. Poverty status (3.0) was found to increase vulnerability while adaptive capacity (-23.8), age (-0.1), education (-0.7), gender (-2.8), distance to market (-0.1), livestock ownership (-0.4), social amenities (-1.9), total livelihood activities (-2.4) and membership of association (-3.8) decreased vulnerability by the percentages indicated in parenthesis. The study therefore recommended that the level of literacy among farm households and availability of social amenities should be critical issues when formulating climate adaptation policies and developmental issues. Government and NGOs should install processes that can enhance the adaptive capacity of the farmers