22,118 research outputs found

    Bounded cohomology via partial differential equations, I

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    A perspective on the economics of natural gas decontrol

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    Natural gas ; Natural resources ; Energy policy

    A master relation defines the nonlinear viscoelasticity of single fibroblasts

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    Cell mechanical functions like locomotion, contraction and division are controlled by the cytoskeleton, a dynamic biopolymer network whose mechanical properties remain poorly understood. We perform single-cell uniaxial stretching experiments on 3T3 fibroblasts. By superimposing small amplitude oscillations on a mechanically prestressed cell, we find a transition from linear viscoelastic behavior to power-law stress stiffening. Data from different cells over several stress decades can be uniquely scaled to obtain a master-relation between the viscoelastic moduli and the average force. Remarkably, this relation holds independently of deformation history, adhesion biochemistry, and intensity of active contraction. In particular, it is irrelevant whether force is actively generated by the cell or externally imposed by stretching. We propose that the master-relation reflects the mechanical behavior of the force bearing actin cytoskeleton, in agreement with stress stiffening known from semiflexible filament networks.Comment: 12 pages, 11 figures. Accepted for publication in Biophysical Journal, scheduled to appear in May 200

    The emergence of coherence in complex networks of heterogeneous dynamical systems

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    We present a general theory for the onset of coherence in collections of heterogeneous maps interacting via a complex connection network. Our method allows the dynamics of the individual uncoupled systems to be either chaotic or periodic, and applies generally to networks for which the number of connections per node is large. We find that the critical coupling strength at which a transition to synchrony takes place depends separately on the dynamics of the individual uncoupled systems and on the largest eigenvalue of the adjacency matrix of the coupling network. Our theory directly generalizes the Kuramoto model of equal strength, all-to-all coupled phase oscillators to the case of oscillators with more realistic dynamics coupled via a large heterogeneous network.Comment: 4 pages, 1 figure. Published versio

    City business cycles and crime

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    We explore the influence of city-level business cycle fluctuations on crime in 20 large cities in the United States. Our monthly time series analysis considers seven crimes over an approximately 20-year period: murder, rape, assault, robbery, burglary, larceny, and motor vehicle theft. Short-run changes in economic conditions, as measured by changes in unemployment and wages, are found to have little effect on city crime across many cities, but property crimes were more likely to be influenced by changes in economic conditions than were more violent crimes. Contrary to the deterrence hypothesis, we find strong evidence that in many cities more arrests follow from an increase in crime rather than arrests leading to a decrease in crime. This is true especially for the more visible crimes of robbery and vehicle theft and suggests that city officials desire to remove these crimes from the public's view.Business cycles ; Cities and towns ; Crime
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