African financial systems: A review

AbstractWe start by providing an overview of financial systems in the African continent. We then consider the regions of Arab North Africa, West Africa, East and Central Africa, and Southern Africa in more detail. The paper covers, among other things, central banks, deposit-taking banks, non-bank institutions, such as the stock markets, fixed income markets, insurance markets, and microfinance institutions

Competitive and Value Effects of Bank Privatization in Developed Countries

This paper presents a comprehensive analysis of the performance of privatized banks in developed countries. Consistent with the competitive effects hypothesis which asserts that privatization could hurt rivals, we find that the rival banks reacted negatively to news of bank privatization in developed countries. The competitive effects are stronger in cases where government ownership decreases significantly. Contrary to the findings of prior studies that examine the performance of privatized banks in developing countries, we find that privatized banks in developed countries experienced significant improvements in operating performance and stock market performance in the post privatization period

African Financial Systems: A Review

We start by providing an overview of financial systems in the African continent. We then consider the regions of Arab North Africa, West Africa, East and Central Africa, and Southern Africa in more detail. The paper covers, among other things, central banks, deposit-taking banks, non-bank institutions, such as the stock markets, fixed income markets, insurance markets, and microfinance institutions

Affective Wellbeing and the Teaching of Music in Ghanaian Basic Schools: A Reflection

Any healthy education aims to develop the individual holistically. To help achieveand assess this goal, educational objectives have been categorized under three domains: cognitive, psychomotor and affective. The arts (music particularly), have been identified as being best suited for the training of the affective domain. Using a number of instruments and triangulation methods, we examined this claim. We observed that music teaching in Ghanaian basic schools has, to a large extent, not fulfilled this mandate. We recommend the need to rethink the music program in two main ways: a) reviewing curricula materials and b) providing requisite training for music teachers

Distribution Network Reconfiguration Considering Feeder Length as a Reliability Index

Power distribution network reconfiguration is achieved by opening or closing sectionalizes and tie switches to optimize a set of objectives. Active loss reduction is the objective in the reconfiguration of distribution networks since distribution networks usually record high levels of power losses. Reliability of the network is also an important objective. In this work, the objective function of the optimization is the reduction of power loss, improvement of line loading index and improvement of reliability. This paper seeks to shift the focus from the traditional objectives of passive (without distributed generations) networks to the security and reliability objectives. Since network reconfiguration is a planning problem, the work was performed to solve the problem for multi – period scenarios which spanned 24hrs. Genetic Algorithm was employed in this study and the simulation was performed in MATLAB software environment using a modified IEEE 69 Bus test system

How Have Consumers Fared in Bank Privatization? International Evidence

We examine whether consumers have benefited from bank privatization worldwide and find that bank spreads are significantly higher in the post privatization period than in the pre-privatization period, suggesting that bank customers have not benefited from bank privatization. However, we observe that the increase in net interest margin occurred in the developed countries whereas consumers in developing countries have benefited from reduced bank margins following privatization. Despite the reduction in bank margins, consumers in developing countries still pay more for banking services than their counterparts in the developed world. Since developed countries banking environment is more competitive, lack of competition does not seem to explain our findings. Rather, the results appear to support the conjecture that margins were perhaps kept artificially low in the pre-privatization period and that the higher margins in the developed countries reflect market conditions

Relevance of genomic diversity of Mycobacterium tuberculosis complex in Africa

BACKGROUND: The diversity in the lineages of Mycobacterium tuberculosis complex (MTBC) was initially considered insignificant. However, comparative genomics analysis of MTBC have found genomic variation among the genotypes with potential phenotypic implications. OBJECTIVE: Therefore, this viewpoint seeks to discuss the impact of the identified genotypic diversity on the physiology of MTBC and the potential implications on TB control. RESULTS: Studies conducted in West Africa and other parts of Africa have unravelled the implications of the genomic diversity on phenotypes such as disease outcome, transmission dynamics and host immune response. The understanding of the phenotypic diversity among the different lineages of MTBC may be an important key to the fight against TB. CONCLUSION: The relevance of these differences has been observed in the design of new control tools such as diagnostics and anti-TB drugs/vaccines. This only points to the fact that the diversity in MTBC cannot be ignored in future studies especially clinical trials for new vaccines and new anti-TB drugs

Molecular epidemiology of Mycobacterium africanum in Ghana

BACKGROUND: Mycobacterium africanum comprises two phylogenetic lineages within the M. tuberculosis complex (MTBC) and is an important cause of human tuberculosis (TB) in West Africa. The reasons for this geographic restriction of M. africanum remain unclear. Here, we performed a prospective study to explore associations between the characteristics of TB patients and the MTBC lineages circulating in Ghana. METHOD: We genotyped 1,211 MTBC isolates recovered from pulmonary TB patients recruited between 2012 and 2014 using single nucleotide polymorphism typing and spoligotyping. Associations between patient and pathogen variables were assessed using univariate and multivariate logistic regression. RESULTS: Of the 1,211 MTBC isolates analysed, 71.9 % (871) belonged to Lineage 4; 12.6 % (152) to Lineage 5 (also known as M. africanum West-Africa 1), 9.2 % (112) to Lineage 6 (also known as M. africanum West-Africa 2) and 0.6 % (7) to Mycobacterium bovis. Univariate analysis revealed that Lineage 6 strains were less likely to be isoniazid resistant compared to other strains (odds ratio = 0.25, 95 % confidence interval (CI): 0.05-0.77, P < 0.01). Multivariate analysis showed that Lineage 5 was significantly more common in patients from the Ewe ethnic group (adjusted odds ratio (adjOR): 2.79; 95 % CI: 1.47-5.29, P < 0.001) and Lineage 6 more likely to be found among HIV-co-infected TB patients (adjOR = 2.2; 95 % confidence interval (CI: 1.32-3.7, P < 0.001). CONCLUSION: Our findings confirm the importance of M. africanum in Ghana and highlight the need to differentiate between Lineage 5 and Lineage 6, as these lineages differ in associated patient variables

Antimycobacterial and cytotoxic activity of selected medicinal plant extracts

AbstractEthnopharmacological relevanceTuberculosis (TB) caused by Mycobacterium tuberculosis remains an ongoing threat to human health. Several medicinal plants are used traditionally to treat tuberculosis in Ghana. The current study was designed to investigate the antimycobacterial activity and cytotoxicity of crude extracts from five selected medicinal plants.Material and methodsThe microplate alamar blue assay (MABA) was used for antimycobacterial studies while the CellTiter 96® AQueous Assay, which is composed of solutions of a novel tetrazolium compound [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt; MTS] and an electron coupling reagent (phenazine methosulfate) PMS, was used for cytotoxic studies. Correlation coefficients were used to compare the activity of crude extracts against nonpathogenic strains and the pathogenic Mycobacterium tuberculosis subsp.tuberculosis.ResultsResults of the MIC determinations indicated that all the crude extracts were active on all the three tested mycobacterial strains. Minimum inhibitory concentration values as low as 156.3µg/mL against M. tuberculosis; Strain H37Ra (ATCC® 25,177™) were recorded from the leaves of Solanum torvum Sw. (Solanaceae). Cytotoxicity of the extracts varied, and the leaves from S. torvum had the most promising selectivity index. Activity against M. tuberculosis; Strain H37Ra was the best predictor of activity against pathogenic Mycobacterium tuberculosis subsp.tuberculosis (correlation coefficient=0.8).ConclusionThe overall results of the present study provide supportive data on the use of some medicinal plants for tuberculosis treatment. The leaves of Solanum torvum are a potential source of anti-TB natural products and deserve further investigations to develop novel anti-TB agents against sensitive and drug resistant strains of M. tuberculosis