217 research outputs found

    Geospatial Analysis and Internet of Things in Environmental Informatics

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    Geospatial analysis offers large potential for better understanding, modelling and visualizing our natural and artificial ecosystems, using Internet of Things as a pervasive sensing infrastructure. This paper performs a review of research work based on the IoT, in which geospatial analysis has been employed in environmental informatics. Six different geospatial analysis methods have been identified, presented together with 26 relevant IoT initiatives adopting some of these techniques. Analysis is performed in relation to the type of IoT devices used, their deployment status and data transmission standards, data types employed, and reliability of measurements. This paper scratches the surface of this combination of technologies and techniques, providing indications of how IoT, together with geospatial analysis, are currently being used in the domain of environmental research.Comment: Applying Internet of Things Technologies in Environmental Research Workshop, Proc. of EnviroInfo 201

    Management of chronic immune thrombocytopenic purpura: targeting insufficient megakaryopoiesis as a novel therapeutic principle

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    Traditionally, anti-platelet autoantibodies accelerating platelet clearance from the peripheral circulation have been recognized as the primary pathopysiological mechanism in chronic immune thrombocytopenia (ITP). Recently, increasing evidence supports the co-existence of insufficient megakaryopoiesis. Inadequate low thrombopoietin (TPO) levels are associated with insufficient proliferation and differentiation of megakaryocytes, decreased proplatelet formation, and subsequent platelet release. Recently two novel activators of TPO receptors have been made available: romiplostim and eltrombopag. In several phase III studies, both agents demonstrated increase of platelet counts in about 80% of chronic ITP patients within 2 to 3 weeks. These agents substantially broaden the therapeutic options for patients with chronic ITP although long-term results are still pending. This review will provide an update on the current conception of underlying mechanisms in ITP and novel, pathophysiologically based treatment options

    Internet of Things in Geospatial Analytics

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    Digital Earth was born with the aim of replicating the real world within the digital world. Many efforts have been made to observe and sense the Earth, both from space and by using in situ sensors. Focusing on the latter, advances in Digital Earth have established vital bridges to exploit these sensors and their networks by taking location as a key element. The current era of connectivity envisions that everything is connected to everything. The concept of the Internet of Things emerged as a holistic proposal to enable an ecosystem of varied, heterogeneous networked objects and devices to speak and interact with each other. To make the IoT ecosystem a reality, it is necessary to understand the electronic components, communication protocols, real-time analysis techniques, and the location of the objects and devices. The IoT ecosystem and the Digital Earth jointly form interrelated infrastructures for addressing modern pressing issues and complex challenges. In this chapter, we explore the synergies and frictions in establishing an efficient and permanent collaboration between the two infrastructures, in order to adequately address multidisciplinary and increasingly complex real-world problems. Although there are still some pending issues, the identified synergies generate optimism for a true collaboration between the Internet of Things and the Digital Earth.Comment: Book chapter at the Manual of Digital Earth Book, ISDE, September 2019, Editors: Huadong Guo, Michael F. Goodchild and Alessandro Annoni, (Publisher: Springer, Singapore

    Uranium in the eastern margin of western Siberian plate, or how to overcome crisis of uranium

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    Теоретические построения [5], свидетельствующие о катагенно-осадочном, эксфильтрационном происхождении железных руд Западно-Сибирского бассейна являются дополнительным фактором принципиальной возможности глубинного происхождения не только радиоактивных металлов, но и ванадия, марганца, благородных металлов и железа. Theoretical constructions [5], which provide evidence of catagenic-aqueous, exfiltration origin of ores of Western Siberian basin, are an additional attribute of principal opportunity for deep seated origin of not only radioactive metals, but also of vanadium, manganese, noble metals and ferrum
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