65 research outputs found

    Estación Intermodal Atocongo - Nueva Centralidad Sur

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    El argumento del presente estudio de investigación radica en el funcionamiento de la Estación Intermodal de Atocongo - Vía Expresa Sur, teniendo como referencia los últimos proyectos de desarrollo urbanístico de Lima Metropolitana, enlazado con los sistemas de transportes actuales y proyectados, de esta forma generando nuevos equipamientos culturales, comerciales, deportivos, recuperando áreas verdes y de uso público que conecten dos bordes y perforen una gran barrera urbana que divide Lima, creando en conjunto un nuevo centro cívico en la zona sur de la ciudad

    Measurement of CP violation parameters and polarisation fractions in Bs0J/ψK0 {\mathrm{B}}_{\mathrm{s}}^0\to \mathrm{J}/\psi {\overline{\mathrm{K}}}^{\ast 0} decays

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    The first measurement of C ⁣P{C\!P} asymmetries in the decay Bs0J/ψK(892)0{B_s^0\to J/\psi \overline{K}^{*}(892)^{0}} and an updated measurement of its branching fraction and polarisation fractions are presented. The results are obtained using data corresponding to an integrated luminosity of 3.0fb13.0\,fb^{-1} of proton-proton collisions recorded with the LHCb detector at centre-of-mass energies of 77 and 8TeV8\,\mathrm{TeV}. Together with constraints from B0J/ψρ0{B^0\to J/\psi \rho^0}, the results are used to constrain additional contributions due to penguin diagrams in the C ⁣P{C\!P}-violating phase ϕs{{\phi}_{s}}, measured through Bs0{B_s^0} decays to charmonium.The first measurement of CP asymmetries in the decay Bs0J/ψK(892)0 {B}_s^0\to J/\psi {\overline{\mathrm{K}}}^{\ast }{(892)}^0 and an updated measurement of its branching fraction and polarisation fractions are presented. The results are obtained using data corresponding to an integrated luminosity of 3.0 fb^{−}^{1} of proton-proton collisions recorded with the LHCb detector at centre-of-mass energies of 7 and 8 TeV. Together with constraints from B0^{0} → J/ψ ρ0^{0}, the results are used to constrain additional contributions due to penguin diagrams in the CP -violating phase ϕs_{s} , measured through Bs0_{s}^{0} decays to charmonium.The first measurement of C ⁣P{C\!P} asymmetries in the decay Bs0J/ψK(892)0{B_s^0\to J/\psi \overline{K}^{*}(892)^{0}} and an updated measurement of its branching fraction and polarisation fractions are presented. The results are obtained using data corresponding to an integrated luminosity of 3.0fb13.0\,fb^{-1} of proton-proton collisions recorded with the LHCb detector at centre-of-mass energies of 77 and 8TeV8\,\mathrm{TeV}. Together with constraints from B0J/ψρ0{B^0\to J/\psi \rho^0}, the results are used to constrain additional contributions due to penguin diagrams in the C ⁣P{C\!P}-violating phase ϕs{{\phi}_{s}}, measured through Bs0{B_s^0} decays to charmonium

    Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

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    Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

    Estación Intermodal Atocongo - Nueva Centralidad Sur

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    Trabajo de suficiencia profesionalEl argumento del presente estudio de investigación radica en el funcionamiento de la Estación Intermodal de Atocongo - Vía Expresa Sur, teniendo como referencia los últimos proyectos de desarrollo urbanístico de Lima Metropolitana, enlazado con los sistemas de transportes actuales y proyectados, de esta forma generando nuevos equipamientos culturales, comerciales, deportivos, recuperando áreas verdes y de uso público que conecten dos bordes y perforen una gran barrera urbana que divide Lima, creando en conjunto un nuevo centro cívico en la zona sur de la ciudad

    Servicios ecosistémicos: un enfoque introductorio con experiencias del occidente colombiano

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    Con el interés de transmitir y apropiar diversas comunidades en temáticas asociadas a los servicios ecosistémicos, el presente libro entrega 15 capítulos que aproximarán al lector hacia la conceptualización y apropiación de conocimientos básicos,&nbsp; asociados a los diversos servicios ecosistémicos brindados generosamente por la naturaleza. El capítulo 1, Introducción al estado del arte de los servicios ecosistémicos en la región occidental colombiana, introduce al lector hacia la apropiación conceptual de los servicios ecosistémicos, contando experiencias relevantes del contexto colombiano. Los 14 capítulos posteriores también tendrán una fase introductoria, estudios de caso basados en experiencias del occidente colombiano y resultados de investigaciones realizadas por los autores. En estos capítulos, el lector encontrará información relevante sobre cuatro grupos de servicios ecosistémicos: abastecimiento, regulación, apoyo y culturales. Este libro es el resultado del arduo trabajo consolidado por un equipo interdisciplinario que, a partir de la integración de saberes y resultados de investigación, logró construir un material de lenguaje sencillo que se espera sea de gran utilidad para diversos lectores interesados en apropiarse del conocimiento básico, orientado hacia la familiarización y el compromiso con la protección de los ecosistemas y sus servicios

    Measurement of CP observables in B± → DK± and B± → Dπ± with two- and four-body D decays

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    Measurement of the mass and lifetime of the Ωb\Omega_b^- baryon

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    A proton-proton collision data sample, corresponding to an integrated luminosity of 3 fb1^{-1} collected by LHCb at s=7\sqrt{s}=7 and 8 TeV, is used to reconstruct 63±963\pm9 ΩbΩc0π\Omega_b^-\to\Omega_c^0\pi^-, Ωc0pKKπ+\Omega_c^0\to pK^-K^-\pi^+ decays. Using the ΞbΞc0π\Xi_b^-\to\Xi_c^0\pi^-, Ξc0pKKπ+\Xi_c^0\to pK^-K^-\pi^+ decay mode for calibration, the lifetime ratio and absolute lifetime of the Ωb\Omega_b^- baryon are measured to be \begin{align*} \frac{\tau_{\Omega_b^-}}{\tau_{\Xi_b^-}} &= 1.11\pm0.16\pm0.03, \\ \tau_{\Omega_b^-} &= 1.78\pm0.26\pm0.04\pm0.05~{\rm ps}, \end{align*} where the uncertainties are statistical, systematic and from the calibration mode (for τΩb\tau_{\Omega_b^-} only). A measurement is also made of the mass difference, mΩbmΞbm_{\Omega_b^-}-m_{\Xi_b^-}, and the corresponding Ωb\Omega_b^- mass, which yields \begin{align*} m_{\Omega_b^-}-m_{\Xi_b^-} &= 247.4\pm3.2\pm0.5~{\rm MeV}/c^2, \\ m_{\Omega_b^-} &= 6045.1\pm3.2\pm 0.5\pm0.6~{\rm MeV}/c^2. \end{align*} These results are consistent with previous measurements.A proton-proton collision data sample, corresponding to an integrated luminosity of 3  fb-1 collected by LHCb at s=7 and 8 TeV, is used to reconstruct 63±9 Ωb-→Ωc0π-, Ωc0→pK-K-π+ decays. Using the Ξb-→Ξc0π-, Ξc0→pK-K-π+ decay mode for calibration, the lifetime ratio and the absolute lifetime of the Ωb- baryon are measured to be τΩb-/τΞb-=1.11±0.16±0.03, τΩb-=1.78±0.26±0.05±0.06  ps, where the uncertainties are statistical, systematic and from the calibration mode (for τΩb- only). A measurement is also made of the mass difference, mΩb--mΞb-, and the corresponding Ωb- mass, which yields mΩb--mΞb-=247.4±3.2±0.5  MeV/c2, mΩb-=6045.1±3.2±0.5±0.6  MeV/c2. These results are consistent with previous measurements.A proton-proton collision data sample, corresponding to an integrated luminosity of 3 fb1^{-1} collected by LHCb at s=7\sqrt{s}=7 and 8 TeV, is used to reconstruct 63±963\pm9 ΩbΩc0π\Omega_b^-\to\Omega_c^0\pi^-, Ωc0pKKπ+\Omega_c^0\to pK^-K^-\pi^+ decays. Using the ΞbΞc0π\Xi_b^-\to\Xi_c^0\pi^-, Ξc0pKKπ+\Xi_c^0\to pK^-K^-\pi^+ decay mode for calibration, the lifetime ratio and absolute lifetime of the Ωb\Omega_b^- baryon are measured to be \begin{align*} \frac{\tau_{\Omega_b^-}}{\tau_{\Xi_b^-}} &= 1.11\pm0.16\pm0.03, \\ \tau_{\Omega_b^-} &= 1.78\pm0.26\pm0.05\pm0.06~{\rm ps}, \end{align*} where the uncertainties are statistical, systematic and from the calibration mode (for τΩb\tau_{\Omega_b^-} only). A measurement is also made of the mass difference, mΩbmΞbm_{\Omega_b^-}-m_{\Xi_b^-}, and the corresponding Ωb\Omega_b^- mass, which yields \begin{align*} m_{\Omega_b^-}-m_{\Xi_b^-} &= 247.4\pm3.2\pm0.5~{\rm MeV}/c^2, \\ m_{\Omega_b^-} &= 6045.1\pm3.2\pm 0.5\pm0.6~{\rm MeV}/c^2. \end{align*} These results are consistent with previous measurements

    Observation of Λb0ψ(2S)pK \Lambda_b^0 \to \psi(2S)pK^- and Λb0J/ψπ+πpK \Lambda_b^0 \to J/\psi \pi^+ \pi^- pK^- decays and a measurement of the Λb0\Lambda_b^0 baryon mass

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    The decays Λb0ψ(2S)pK \Lambda_b^0 \to \psi(2S)pK^- and Λb0J/ψπ+πpK \Lambda_b^0 \to J/\psi \pi^+ \pi^- pK^- are observed in a data sample corresponding to an integrated luminosity of 3fb1^{-1}, collected in proton-proton collisions at 7 and 8TeV centre-of-mass energies by the LHCb detector. The ψ(2S)\psi(2S) mesons are reconstructed through the decay modes ψ(2S)μ+μ\psi(2S)\to\mu^+\mu^- and ψ(2S)J/ψπ+π\psi(2S)\to J/\psi\pi^+\pi^-. The branching fractions relative to that of Λb0J/ψpK \Lambda_b^0 \to J/\psi pK^- are measured to be \begin{eqnarray*} \frac{\mathcal{B}(\Lambda_b^0 \to \psi(2S) pK^-)} {\mathcal{B}(\Lambda_b^0 \to J/\psi pK^-)} & = & (20.70\pm 0.76\pm 0.46\pm 0.37)\times10^{-2} \,, \frac{\mathcal{B}(\Lambda_b^0 \to J/\psi \pi^+ \pi^- pK^-)} {\mathcal{B}(\Lambda_b^0 \to J/\psi pK^-)} & = & (20.86\pm 0.96\pm 1.34)\times10^{-2} \,, \end{eqnarray*} where the first uncertainties are statistical, the second are systematic and the third is related to the knowledge of J/ψJ/\psi and ψ(2S)\psi(2S) branching fractions. The mass of the Λb0\Lambda_b^0 baryon is measured to beThe decays Λb0_{b}^{0}  → ψ(2S)pK^{−} and Λb0_{b}^{0}  → J/ψπ+^{+} π^{−}pK^{−} are observed in a data sample corresponding to an integrated luminosity of 3 fb1^{−1}, collected in proton-proton collisions at 7 and 8 TeV centre-of-mass energies by the LHCb detector. The ψ(2S) mesons are reconstructed through the decay modes ψ(2S) → μ+^{+}μ^{−} and ψ(2S) → J/ψπ+^{+} π^{−}.The decays Λb0ψ(2S)pK \Lambda_b^0 \to \psi(2S)pK^- and Λb0J/ψπ+πpK \Lambda_b^0 \to J/\psi \pi^+ \pi^- pK^- are observed in a data sample corresponding to an integrated luminosity of 3fb1^{-1}, collected in proton-proton collisions at 7 and 8TeV centre-of-mass energies by the LHCb detector. The ψ(2S)\psi(2S) mesons are reconstructed through the decay modes ψ(2S)μ+μ\psi(2S)\to\mu^+\mu^- and ψ(2S)J/ψπ+π\psi(2S)\to J/\psi\pi^+\pi^-. The branching fractions relative to that of Λb0J/ψpK \Lambda_b^0 \to J/\psi pK^- are measured to be \begin{eqnarray*} \frac{\mathcal{B}(\Lambda_b^0 \to \psi(2S) pK^-)} {\mathcal{B}(\Lambda_b^0 \to J/\psi pK^-)} & = & (20.70\pm 0.76\pm 0.46\pm 0.37)\times10^{-2} \,, \frac{\mathcal{B}(\Lambda_b^0 \to J/\psi \pi^+ \pi^- pK^-)} {\mathcal{B}(\Lambda_b^0 \to J/\psi pK^-)} & = & (20.86\pm 0.96\pm 1.34)\times10^{-2} \,, \end{eqnarray*} where the first uncertainties are statistical, the second are systematic and the third is related to the knowledge of J/ψJ/\psi and ψ(2S)\psi(2S) branching fractions. The mass of the Λb0\Lambda_b^0 baryon is measured to be M(Λb0)=5619.65±0.17±0.17MeV/c2, M(\Lambda_b^0) = 5619.65 \pm 0.17 \pm 0.17\mathrm{MeV}/c^2, where the uncertainties are statistical and systematic

    First observation of D0Dˉ0D^0- \bar D^0 oscillations in D0K+ππ+πD^0 \to K^+\pi^-\pi^+\pi^- decays and measurement of the associated coherence parameters

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    Charm meson oscillations are observed in a time-dependent analysis of the ratio of D0K+ππ+πD^0\to K^+\pi^-\pi^+\pi^- to D0Kπ+ππ+D^0\to K^-\pi^+\pi^-\pi^+ decay rates, using data corresponding to an integrated luminosity of 3.0fb13.0\,{\rm fb}^{-1} recorded by the LHCb experiment. The measurements presented are sensitive to the phase-space averaged ratio of doubly Cabibbo-suppressed to Cabibbo-favoured amplitudes rDK3πr_{D}^{K3\pi} and the product of the coherence factor RDK3πR_{D}^{K3\pi} and a charm mixing parameter yK3πy^{'}_{K3\pi}. The constraints measured are rDK3π=(5.67±0.12)×102r_{D}^{K3\pi}=(5.67 \pm 0.12)\times10^{-2}, which is the most precise determination to date, and RDK3πyK3π=(0.3±1.8)×103R_{D}^{K3\pi} \cdot y^{'}_{K3\pi} = (0.3 \pm 1.8)\times 10^{-3}, which provides useful input for determinations of the CP-violating phase γ\gamma in B±DK±,DKπ±ππ±B^\pm \to D K^\pm, D \to K^\mp\pi^\pm\pi^\mp\pi^\pm decays. The analysis also gives the most precise measurement of the D0K+ππ+πD^0\to K^+\pi^-\pi^+\pi^- branching fraction, and the first observation of D0Dˉ0D^0-\bar D^0 oscillations in this decay mode, with a significance of 8.2 standard deviations.Charm meson oscillations are observed in a time-dependent analysis of the ratio of D0→K+π-π+π- to D0→K-π+π-π+ decay rates, using data corresponding to an integrated luminosity of 3.0  fb-1 recorded by the LHCb experiment. The measurements presented are sensitive to the phase-space averaged ratio of doubly Cabibbo-suppressed to Cabibbo-favored amplitudes rDK3π and the product of the coherence factor RDK3π and a charm mixing parameter yK3π′. The constraints measured are rDK3π=(5.67±0.12)×10-2, which is the most precise determination to date, and RDK3πyK3π′=(0.3±1.8)×10-3, which provides useful input for determinations of the CP-violating phase γ in B±→DK±, D→K∓π±π∓π± decays. The analysis also gives the most precise measurement of the D0→K+π-π+π- branching fraction, and the first observation of D0–D¯0 oscillations in this decay mode, with a significance of 8.2 standard deviations.Charm meson oscillations are observed in a time-dependent analysis of the ratio of D0K+ππ+πD^0\to K^+\pi^-\pi^+\pi^- to D0Kπ+ππ+D^0\to K^-\pi^+\pi^-\pi^+ decay rates, using data corresponding to an integrated luminosity of 3.0fb13.0\,{\rm fb}^{-1} recorded by the LHCb experiment. The measurements presented are sensitive to the phase-space averaged ratio of doubly Cabibbo-suppressed to Cabibbo-favoured amplitudes rDK3πr_{D}^{K3\pi} and the product of the coherence factor RDK3πR_{D}^{K3\pi} and a charm mixing parameter yK3πy^{'}_{K3\pi}. The constraints measured are rDK3π=(5.67±0.12)×102r_{D}^{K3\pi}=(5.67 \pm 0.12)\times10^{-2}, which is the most precise determination to date, and RDK3πyK3π=(0.3±1.8)×103R_{D}^{K3\pi} \cdot y^{'}_{K3\pi} = (0.3 \pm 1.8)\times 10^{-3}, which provides useful input for determinations of the CP-violating phase γ\gamma in B±DK±,DKπ±ππ±B^\pm \to D K^\pm, D \to K^\mp\pi^\pm\pi^\mp\pi^\pm decays. The analysis also gives the most precise measurement of the D0K+ππ+πD^0\to K^+\pi^-\pi^+\pi^- branching fraction, and the first observation of D0Dˉ0D^0-\bar D^0 oscillations in this decay mode, with a significance of 8.2 standard deviations
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