Trabajo Social con familias y conflicto familia-trabajo

The article analyses the direct and modulating effects of family support on burnout in the work-family conflict in Spanish middle-class families. The analysis has been separated by gender in order to better examine differences. Direct relationships in the data show that family support is negatively related to the two subscales of burnout, especially in women. Regarding the buffer effect on work-family conflict, gender differences were found: in men, as expected, support reduced the perception of lack of self-efficacy, however, in women, when the conflict was due to stress or tension, the support had positive effects. If the conflict was due to time, a reverse effect could be found and support was negative. These results confirm the importance of addressing a conflict that is emerging as a major stressor and increasingly prevalent in the field of social services to families. It is a stressor that has increased its presence as a result of the current economic crisis.El artículo analiza el efecto directo y modulador del apoyo familiar sobre el burnout en el conflicto entre la familia y el trabajo en familias de clase media española, haciendo análisis separados en función del género para analizar mejor las diferencias. Las relaciones directas muestran sobre todo en las mujeres, que el apoyo familiar se relaciona negativamente con las dos subescalas del burnout. Respecto al papel amortiguador del apoyo familiar sobre los efectos del conflicto familia-trabajo se observan también diferencias de género: en los hombres como se esperaba, el apoyo reduce su percepción de falta de autoeficacia, sin embargo, en las mujeres cuando el conflicto es por estrés o tensión, el apoyo es positivo. Y si el conflicto es por tiempo, el apoyo es negativo, mostrando un efecto reverso. Estos resultados confirman la importancia de atender a un conflicto que se perfila como un estresor importante y cada vez más prevalente en el ámbito de los servicios de asistencia social a las familias. Un estresor que ha aumentado su presencia como consecuencia de la actual crisis económica

Social Work with Families and Work-Family Conflict

The article analyses the direct and modulating effects of family support on burnout in the work-family conflict in Spanish middle-class families. The analysis has been separated by gender in order to better examine differences. Direct relationships in the data show that family support is negatively related to the two subscales of burnout, especially in women. Regarding the buffer effect on work-family conflict, gender differences were found: in men, as expected, support reduced the perception of lack of self-efficacy, however, in women, when the conflict was due to stress or tension, the support had positive effects. If the conflict was due to time, a reverse effect could be found and support was negative. These results confirm the importance of addressing a conflict that is emerging as a major stressor and increasingly prevalent in the field of social services to families. It is a stressor that has increased its presence as a result of the current economic crisis.</p

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality