3 research outputs found
Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming
The limited therapeutic options available for hepatocellular carcinoma (HCC) make mandatory to find alternative effective treatments for this tumor. Based on the recent finding that systemic or local hypothyroidism is associated with HCC development in humans and rodents, we investigated whether the thyroid hormone triiodothyronine (T3) could inhibit the progression of hepatocellular carcinomas (HCCs)
Geomorphological map of the Italian coast: From a descriptive to a morphodynamic approach.
This study was conducted within the framework of the \u201cCoastal Morphodynamics\u201d Working Group (WG) of the Italian Association of physical
Geography and Geomorphology (AIGeo), according to the Institute for the Protection and Environmental Research (ISPRA) for the updating
of the legend for the \u201cGeomorphological Map of Italy\u201d. The WG deals with the legend for the coastal areas, focusingits work on marine, lagoon
and aeolian landforms, processes and deposits. In particular, the legend aims to classify coastal landforms in order to contribute to hazard and risk assessment,for supportingland-use planning and management. The legend allows the mapping of each landform in function of its genesis as well as its evolution and present dynamics, providing information about morphological characteristics at small and large scales. The relict morphological features and the active ones are reported along with the quantitative parameters useful for the description of the present wave/climate conditions and morphodynamics. As a result of the activities and experiments carried out by the \u201cCoastal Morphodynamics\u201d AIGeo WG during the last years, some examples of coastal geomorphological mappings at different scales (1:5,000 and 1:25,000) have been developed and are presented in this paper. The maps focus both on littoral plains and rocky coast dynamics as well as on the interactions with anthropic modifications