Linear Collider Final Doublet Considerations: ATF2 Vibration Measurements

Original publication available at http://www.jacow.org/International audienceAt ATF2, to allow the Shintake Monitor located at the Interaction Point to measure the beam size with only 2% of error, vertical relative motion tolerance between SM (Shintake Monitor) and final doublet magnets (FD) is of 7nm for QD0 and 20nm for QF1 above 0.1Hz. Vibration transfer function of FD and SM with their supports has been measured and show a good rigidity. Vertical relative motion between the SM and QD0 (QF1) was thus measured to be only of 5.1nm (6.5nm) with high ground motion representative of a shift period. Same measurements done in horizontal directions showed that tolerances were also respected (much less strict). Moreover, relative motion tolerances should be released due to the good motion correlation measured between FD. Thus the FD and SM supports have been validated on site at ATF2 to be within the vibration specifications

Nanometer Order of Stabilization for Precision Beam Size Monitor (Shintake Monitor)

Original publication available at http://www.jacow.org/International audienceA precision beam size monitor using interference fringes as a reference called Shintake monitor[1] has been developed. Relative position between the beam and the interference fringes should be stabilized within few nm to measure the beam size of 37 nm with resolution of better than 10%. This paper presents concept and performances for stabilization of the Shintake monitor with respect to vibrations. We stabilized the table for the interferometer using a method, "Rigid mount on floor", and the table motions relative to the floor are estimated to be 2 and 6 n

Performance studies of the final prototype for the CASTOR forward calorimeter at the CMS experiment

We present performance results of the final prototype for the CASTOR quartz-tungsten sampling calorimeter, to be installed in the very forward region of the CMS experiment at the LHC. The energy linearity and resolution, the uniformity, as well as the spatial resolution of the prototype to electromagnetic and hadronic showers are studied with $E=$ 10--200 GeV electrons, $E=$ 20--350 GeV pions, and $E=$ 50, 150 GeV muons in beam tests carried out at CERN/SPS in 2007

ATF2 COMMISSIONING

ATF2 is a final-focus test beam line that aims to focus the low-emittance beam from the ATF damping ring to a beam size of about 37 nm, and at the same time to demonstrate nm beam stability, using numerous advanced beam diagnostics and feedback tools. The construction has been finished at the end of 2008 and the beam commissioning of ATF2 has started in December of 2008. ATF2 is constructed and commissioned by ATF international collaborations with strong US, Asian and European participation

Linear Collider Final Doublet Considerations: ATF2 Vibration Measurements

Original publication available at http://www.jacow.org/International audienceAt ATF2, to allow the Shintake Monitor located at the Interaction Point to measure the beam size with only 2% of error, vertical relative motion tolerance between SM (Shintake Monitor) and final doublet magnets (FD) is of 7nm for QD0 and 20nm for QF1 above 0.1Hz. Vibration transfer function of FD and SM with their supports has been measured and show a good rigidity. Vertical relative motion between the SM and QD0 (QF1) was thus measured to be only of 5.1nm (6.5nm) with high ground motion representative of a shift period. Same measurements done in horizontal directions showed that tolerances were also respected (much less strict). Moreover, relative motion tolerances should be released due to the good motion correlation measured between FD. Thus the FD and SM supports have been validated on site at ATF2 to be within the vibration specifications

Efficacy of everolimus in ABO-incompatible kidney transplantation: a retrospective study

Kazuma Tsujimura,1 Morihito Ota,1 Kiyoshi Chinen,1 Kiyomitsu Nagayama,2 Masato Oroku,2 Morikuni Nishihira,2 Yoshiki Shiohira,2 Kunitoshi Iseki,3 Hideki Ishida,4 Kazunari Tanabe4 1Department of Surgery, 2Department of Nephrology, 3Clinical Research Support Center, Tomishiro Central Hospital, Okinawa, Japan; 4Department of Urology, Tokyo Women’s Medical University, Tokyo, Japan Background: There are limited reports on the use of everolimus for maintaining immunosuppression in ABO-incompatible (ABOi) kidney transplantation (KT). As everolimus (EVR) is effective for preventing calcineurin inhibitor (CNI) nephrotoxicity without increasing the risk of chronic rejection and viral infection, we aimed to assess the efficacy of EVR in ABOi KT.Patients and methods: We retrospectively studied 22 patients who underwent KT and received EVR. Patients in the ABOi KT group (n=7) were compared with those in the ABO-compatible kidney transplantation group (ABOc KT; n=15). We recorded the frequency of CNI nephrotoxicity, chronic rejection, and viral infection in the 2 groups.Results: CNI nephrotoxicity, chronic rejection, and viral infection occurred in the ABOi KT and ANOc KT groups at rates of 28.3% (2/7 patients) and 13.3% (2/15 patients) (P=0.388), 28.3% (2/7 patients) and 26.7% (4/15 patients) (P=0.926), and 14.3% (1/7 patients) and 26.7% (4/15 patients) (P=0.517), respectively.Conclusion: Administration of EVR is effective in preventing CNI nephrotoxicity after KT. The rate of CNI nephrotoxicity was lower in the ABOc KT group than in the ABOi KT group. The rate of chronic rejection and viral infection was comparable between the groups. This study was conducted in a small cohort of patients. Hence, further evaluation with large sample sizes is necessary in the future to confirm the outcomes. Keywords: blood group incompatibility, immunosuppression, kidney transplantatio