La microbiota intestinal y su relación en el cáncer gástrico: Un enfoque en la composición microbiana y terapias dirigidas

The intestinal microbiota, also known as intestinal flora, is a diverse community of microorganisms that inhabit our gastrointestinal tract. In recent years, there has been a growing interest in understanding the relationship between the intestinal microbiota and gastric cancer, a form of cancer that affects the stomach. Several studies have shown that there is an association between the composition of the intestinal microbiota and the development, progression, and response to treatment of gastric cancer. It has been observed that certain microorganisms may be present in greater or lesser numbers in patients with gastric cancer compared to healthy individuals. This alteration in the microbial composition can trigger chronic inflammatory responses, promote carcinogenesis and affect the efficacy of treatments. Targeted therapies to modify it have also been explored with the aim of preventing or treating gastric cancer.La microbiota intestinal, también conocida como flora intestinal, es una comunidad diversa de microorganismos que habita en nuestro tracto gastrointestinal. En los últimos años, ha surgido un creciente interés en comprender la relación entre la microbiota intestinal y el cáncer gástrico, una forma de cáncer que afecta el estómago. Varios estudios han demostrado que existe una asociación entre la composición de la microbiota intestinal y el desarrollo, progresión y respuesta al tratamiento del cáncer gástrico. Se ha observado que ciertos microorganismos pueden estar presentes en mayor o menor cantidad en pacientes con cáncer gástrico en comparación con individuos sanos. Esta alteración en la composición microbiana puede desencadenar respuestas inflamatorias crónicas, promover la carcinogénesis y afectar la eficacia de los tratamientos. También se han explorado terapias dirigidas a modificarla con el objetivo de prevenir o tratar el cáncer gástrico

Complications of Laparoscopic Surgery in patients with Obesity

La cirugía laparoscópica, aunque ampliamente utilizada y menos invasiva, presenta desafíos particulares en pacientes con obesidad. En este artículo abordaremos las complicaciones quirúrgicas mediante la técnica de laparoscopía que se podrían producir en el paciente obeso, como en el caso de pacientes ginecológicos con obesidad, se enfrentan a complicaciones como la dificultad en la visualización de estructuras debido al exceso de tejido adiposo. Además, la manipulación de instrumentos en espacios reducidos puede aumentar el riesgo de lesiones en órganos circundantes. En pacientes con colelitiasis, la obesidad puede complicar la identificación y extracción de la vesícula biliar debido a la anatomía alterada.  La presencia de la Enfermedad Intestinal Inflamatoria también agrega complejidad, ya que el tejido inflamado puede obstaculizar la visualización y manipulación durante la cirugía laparoscópica. Adicionalmente, la obesidad en estos pacientes aumenta el riesgo de complicaciones postoperatorias, incluyendo infecciones y problemas respiratorios. Resulta esencial que los cirujanos ponderen minuciosamente estos factores al planificar y llevar a cabo los procedimientos laparoscópicos en pacientes con obesidad, implementando enfoques adaptados y precauciones adicionales para mitigar riesgos.Laparoscopic surgery, although widely used and less invasive, presents particular challenges in patients with obesity. In this article we will address the surgical complications using the laparoscopy technique that could occur in obese patients, as in the case of gynecological patients with obesity, they face complications such as difficulty in visualizing structures due to excess adipose tissue. Additionally, handling instruments in confined spaces may increase the risk of injury to surrounding organs. In patients with cholelithiasis, obesity may complicate the identification and removal of the gallbladder due to altered anatomy. The presence of Inflammatory Bowel Disease also adds complexity, as inflamed tissue can hinder visualization and manipulation during laparoscopic surgery. Additionally, obesity in these patients increases the risk of postoperative complications, including infections and respiratory problems. It is essential that surgeons carefully consider these factors when planning and carrying out laparoscopic procedures in patients with obesity, implementing adapted approaches and additional precautions to mitigate risks

Fungal planet description sheets: 716–784

Novel species of fungi described in this study include those from various countries as follows: Australia, Chaetopsina eucalypti on Eucalyptus leaf litter, Colletotrichum cobbittiense from Cordyline stricta × C. australis hybrid, Cyanodermella banksiae on Banksia ericifolia subsp. macrantha, Discosia macrozamiae on Macrozamia miquelii, Elsinoë banksiigena on Banksia marginata, Elsinoë elaeocarpi on Elaeocarpus sp., Elsinoë leucopogonis on Leucopogon sp., Helminthosporium livistonae on Livistona australis, Idriellomyces eucalypti (incl. Idriellomyces gen. nov.) on Eucalyptus obliqua, Lareunionomyces eucalypti on Eucalyptus sp., Myrotheciomyces corymbiae (incl. Myrotheciomyces gen. nov., Myrotheciomycetaceae fam. nov.), Neolauriomyces eucalypti (incl. Neolauriomyces gen. nov., Neolauriomycetaceae fam. nov.) on Eucalyptus sp., Nullicamyces eucalypti (incl. Nullicamyces gen. nov.) on Eucalyptus leaf litter, Oidiodendron eucalypti on Eucalyptus maidenii, Paracladophialophora cyperacearum (incl. Paracladophialophoraceae fam. nov.) and Periconia cyperacearum on leaves of Cyperaceae, Porodiplodia livistonae (incl. Porodiplodia gen. nov., Porodiplodiaceae fam. nov.) on Livistona australis, Sporidesmium melaleucae (incl. Sporidesmiales ord. nov.) on Melaleuca sp., Teratosphaeria sieberi on Eucalyptus sieberi, Thecaphora aus-traliensis in capsules of a variant of Oxalis exilis. Brazil, Aspergillus serratalhadensis from soil, Diaporthe pseudo-inconspicua from Poincianella pyramidalis, Fomitiporella pertenuis on dead wood, Geastrum magnosporum on soil, Marquesius aquaticus (incl. Marquesius gen. nov.) from submerged decaying twig and leaves of unidentified plant, Mastigosporella pigmentata from leaves of Qualea parviflorae, Mucor souzae from soil, Mycocalia aquaphila on decaying wood from tidal detritus, Preussia citrullina as endophyte from leaves of Citrullus lanatus, Queiroziella brasiliensis (incl. Queiroziella gen. nov.) as epiphytic yeast on leaves of Portea leptantha, Quixadomyces cearen-sis (incl. Quixadomyces gen. nov.) on decaying bark, Xylophallus clavatus on rotten wood. Canada, Didymella cari on Carum carvi and Coriandrum sativum. Chile, Araucasphaeria foliorum (incl. Araucasphaeria gen. nov.) on Araucaria araucana, Aspergillus tumidus from soil, Lomentospora valparaisensis from soil. Colombia, Corynespora pseudocassiicola on Byrsonima sp., Eucalyptostroma eucalyptorum on Eucalyptus pellita, Neometulocladosporiella eucalypti (incl. Neometulocladosporiella gen. nov.) on Eucalyptus grandis × urophylla, Tracylla eucalypti (incl. Tracyllaceae fam. nov., Tracyllalales ord. nov.) on Eucalyptus urophylla. Cyprus, Gyromitra anthracobia (incl. Gyromitra subg. Pseudoverpa) on burned soil. Czech Republic, Lecanicillium restrictum from the surface of the wooden barrel, Lecanicillium testudineum from scales of Trachemys scripta elegans. Ecuador, Entoloma yanacolor and Saproamanita quitensis on soil. France, Lentithecium carbonneanum from submerged decorticated Populus branch. Hungary, Pleuromyces hungaricus (incl. Pleuromyces gen. nov.) from a large Fagus sylvatica log. Iran, Zymoseptoria crescenta on Aegilops triuncialis. Malaysia, Ochroconis musicola on Musa sp. Mexico, Cladosporium michoacanense from soil. New Zealand, Acrodontium metrosideri on Metrosideros excelsa, Polynema podocarpi on Podocarpus totara, Pseudoarthrographis phlogis (incl. Pseudoarthrographis gen. nov.) on Phlox subulata. Nigeria, Coprinopsis afrocinerea on soil. Pakistan, Russula mansehraensis on soil under Pinus roxburghii. Russia, Baoran­ gia alexandri on soil in deciduous forests with Quercus mongolica. South Africa, Didymocyrtis brachylaenae on Brachylaena discolor. Spain, Alfaria dactylis from fruit of Phoenix dactylifera, Dothiora infuscans from a blackened wall, Exophiala nidicola from the nest of an unidentified bird, Matsushimaea monilioides from soil, Terfezia morenoi on soil. United Arab Emirates, Tirmania honrubiae on soil. USA, Arxotrichum wyomingense (incl. Arxotrichum gen. nov.) from soil, Hongkongmyces snookiorum from submerged detritus from a fresh water fen, Leratiomyces tesquorum from soil, Talaromyces tabacinus on leaves of Nicotiana tabacum. Vietnam, Afroboletus vietnamensis on soil in an evergreen tropical forest, Colletotrichum condaoense from Ipomoea pes-caprae. Morphological and culture characteristics along with DNA barcodes are provided. © 2018 Naturalis Biodiversity Center & Westerdijk Fungal Biodiversity Institute