3,230 research outputs found

    A scaled boundary finite element formulation for poroelasticity

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    This paper develops the scaled boundary finite element formulation for applications in coupled field problems, in particular, to poroelasticity. The salient feature of this formulation is that it can be applied over arbitrary polygons and/or quadtree decomposition, which is widely employed to traverse between small and large scales. Moreover, the formulation can treat singularities of any order. Within this framework, 2 sets of semianalytical, scaled boundary shape functions are used to interpolate the displacement and the pore fluid pressure. These shape functions are obtained from the solution of vector and scalar Laplacian, respectively, which are then used to discretise the unknown field variables similar to that of the finite element method. The resulting system of equations are similar in form as that obtained using standard procedures such as the finite element method and, hence, solved using the standard procedures. The formulation is validated using several numerical benchmarks to demonstrate its accuracy and convergence properties

    Adaptive analysis using scaled boundary finite element method in 3D

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    In this paper, an adaptive refinement technique using the scaled boundary finite element method (SBFEM) is proposed. The salient feature of this technique is that it is not required to regenerate the mesh for the whole model during the iterations. To this end, a local mesh refinement strategy is implemented based on a polytree algorithm in three dimensions, which can be applied to polyhedral elements with arbitrary number of nodes, edges and faces. These elements constructed by the SBFEM can be used in analysis with their boundaries discretized only, which reduce the difficulty to connect elements with different sizes. An explicit residual based error indicator is developed using the discontinuity of the stress field to guide the adaptive mesh refinement. The accuracy and efficiency of the proposed method are demonstrated using five numerical examples, including complex geometry and stress singularity

    Isolation of a potential anticancer agent with protein phosphatase inhibitory activity from soil-derived Penicillium sp. strain H9318

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    Purpose: To determine the effect of the secondary metabolites from Penicillium sp. H9318 on cytotoxicity and cell cycle progression. Methods: A yeast PP1 inhibitory screening system was carried out to confirm the presence of anti-PP1c activity in crude acetone extracts of strain H9318. The extracts were fractionated and identified as Fraction S1 and Citrinin 9318 (CTN9318). Various cancer cell lines were used to test for the toxicity of the crude acetone extracts, Fraction S1 and Citrinin 9318, using MTT viability assay. Results: It was found that a colorectal cancer cell line, HT-29, was susceptible to Fraction S1 and Citrinin 9318. A propidium iodide (PI)-incorporated DNA assay was used to show that there was G2/M arrest in HT-29 by Citrinin 9318. Conclusion: Citrinin 9318 inhibits the viability of HT-29 via mitotic block. The results suggest that Citrinin 9318 is capable of exerting cytotoxicity and mitotic arrest in a colon cancer cell line, HT29

    An adaptive scaled boundary finite element method for contact analysis

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    In this work, we propose a framework for an adaptive contact analysis in deformable solids using the effective error indicator from the scaled boundary finite element method (SBFEM) with a quadtree decomposition. Further, the SBFEM is implemented with the commercial finite element software, Abaqus, to perform the contact analysis by employing the user element subroutine (UEL) feature. The SBFEM error indicator coupled with the quadtree decomposition is implemented in Matlab and allowed to interact with the Abaqus using .inp file for an adaptive refinement. The detailed implementation of the framework, input data format, and the UEL subroutine which is one of the key features of the proposed work are clearly explained. The effectiveness of the proposed framework is demonstrated by solving several contact problems of engineering significance. The developed SBFEM code can be downloaded from https://github.com/nsundar/sbfem

    Gravitational radiation from nonaxisymmetric spherical Couette flow in a neutron star

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    The gravitational wave signal generated by global, nonaxisymmetric shear flows in a neutron star is calculated numerically by integrating the incompressible Navier--Stokes equation in a spherical, differentially rotating shell. At Reynolds numbers \Rey \gsim 3 \times 10^{3}, the laminar Stokes flow is unstable and helical, oscillating Taylor--G\"ortler vortices develop. The gravitational wave strain generated by the resulting kinetic-energy fluctuations is computed in both ++ and ×\times polarizations as a function of time. It is found that the signal-to-noise ratio for a coherent, 10810^{8}-{\rm s} integration with LIGO II scales as 6.5(Ω/104rads1)7/2 6.5 (\Omega_*/10^{4} {\rm rad} {\rm s}^{-1})^{7/2} for a star at 1 {\rm kpc} with angular velocity Ω\Omega_*. This should be regarded as a lower limit: it excludes pressure fluctuations, herringbone flows, Stuart vortices, and fully developed turbulence (for \Rey \gsim 10^{6}).Comment: (1) School of Physics, University of Melbourne, Parkville, VIC 3010, Australia. (2) Departamento de Fisica, Escuela de Ciencias,Universidad de Oriente, Cumana, Venezuela, (3) Department of Mechanical Engineering, University of Melbourne, Parkville, VIC 3010, Australia. Accepted for publication in The Astrophysical Journal Letter

    Acceleration effects of microbial inoculum on palm oil mill organic waste composting.

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    ABSTRACT The acceleration effects of inoculum in composting of empty fruit bunches were investigated. Composting of empty fruit bunches fibres in two sizes, 4 cm and 2 cm length, were treated with microbial inoculum consisting of Agromonas, Aspergillus, Azotobacter, Bacillus, Celhdomonas, Chaetomium, Clostridium, Coprinus, Microbispora, Penicillium, Pseudomonas, Thermoactinomyces, Trichoderma and Trichurus in separate laboratory scale in-vessel of 30 liters volume. A control without inoculum with 4 cm length empty fruit bunches was also conducted in parallel. The compost piles were shift-turned weekly. Parameters such as moisture content, temperature, pH, and electrical conductivity were used to monitor the composting processes. The carbon-nitrogen ratio, UV-vis spectrophotometer test, and germination test were used to assess the maturity of compost. The results showed that the inoculum was effective in reducing the C/N ratio by 54% compared to control 46% and rapidly increasing the UV-vis absorption ratio in first three weeks. By using functional microbes, the composting of empty fruit bunches was reduced to 5 weeks compared to 9 weeks for those without inoculation. The acceleration effect was more prominent for the 2 cm length samples
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