299 research outputs found

    Measuring method of loss for optical waveguides by use of a rectangular glass probe

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    The use of a glass-plate probe of rectangular shape is proposed for the measurement of transmission loss in thin-film optical waveguides. The light-collecting window is of a thin rectanglar shape perpendicular to the light streak, while the conventional fiber probe has a very small circular face. This transversely elongated form results in a great improvement of the mechanical tolerance for the probe movement in the vertical as well as the transverse direction. Theoretical investigation is also presented in reasonable agreement with the experiments

    Wide-Supply-Range All-Digital Leakage Variation Sensor for On-Chip Process and Temperature Monitoring

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    Variation in process, voltage and temperature is a major obstacle in achieving energy-efficient operation of LSI. This paper proposes an all-digital on-chip circuit to monitor leakage current variations of both of the nMOSFET and pMOSFET independently. As leakage current is highly sensitive to threshold voltage and temperature, the circuit is suitable for tracking process and temperature variation. The circuit uses reconfigurable inhomogeneity to obtain statistical properties from a single monitor instance. A compact reconfigurable inverter topology is proposed to implement the monitor circuit. The compact and digital nature of the inverter enables cell-based design, which will reduce design costs. Measurement results from a 65 nm test chip show the validity of the proposed circuit. For a 124 sample size for both of the nMOSFET and pMOSFET, the monitor area is 4500 ΞΌm2 and active power consumption is 76 nW at 0.8 V operation. The proposed technique enables area-efficient and low-cost implementation thus can be used in product chips for applications such as dynamic energy and thermal management, testing and post-silicon tuning

    Upper and lower limb muscle atrophy in critically ill patients : an observational ultrasonography study

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    Three novel oligosaccharides synthesized using Thermoanaerobacter brockii kojibiose phosphorylase

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    <p>Abstract</p> <p>Background</p> <p>Recently synthesized novel oligosaccharides have been produced primarily by hydrolases and glycosyltransferases, while phosphorylases have also been subject of few studies. Indeed, phosphorylases are expected to give good results via their reversible reaction. The purpose of this study was to synthesis other novel oligosaccharides using kojibiose phosphorylase.</p> <p>Results</p> <p>Three novel oligosaccharides were synthesized by glucosyltransfer from Ξ²-D-glucose 1-phosphate (Ξ²-D-G1P) to xylosylfructoside [<it>O</it>-Ξ±-D-xylopyranosyl-(1β†’2)-Ξ²-D-fructofuranoside] using <it>Thermoanaerobacter brockii </it>kojibiose phosphorylase. These oligosaccharides were isolated using carbon-Celite column chromatography and preparative high performance liquid chromatography. Gas liquid chromatography analysis of methyl derivatives, MALDI-TOF MS and NMR measurements were used for structural characterisation. The <sup>1</sup>H and <sup>13</sup>C NMR signals of each saccharide were assigned using 2D-NMR including COSY (correlated spectroscopy), HSQC (herteronuclear single quantum coherence), CH<sub>2</sub>-selected E-HSQC (CH<sub>2</sub>-selected Editing-HSQC), HSQC-TOCSY (HSQC-total correlation spectroscopy) and HMBC (heteronuclear multiple bond correlation).</p> <p>Conclusion</p> <p>The structure of three synthesized saccharides were determined, and these oligosaccharides have been identified as <it>O</it>-Ξ±-D-glucopyranosyl-(1β†’2)-<it>O</it>-Ξ±-D-xylopyranosyl-(1β†’2)-Ξ²-D-fructofuranoside (saccharide <b>1</b>), <it>O</it>-Ξ±-D-glucopyranosyl-(1β†’2)-<it>O</it>-Ξ±-D-glucopyranosyl-(1β†’2)-<it>O</it>-Ξ±-D-xylopyranosyl-(1β†’2)-Ξ²-D-fructofuranoside (saccharide <b>2</b>) and <it>O</it>-Ξ±-D-glucopyranosyl-(1β†’[2-<it>O</it>-Ξ±-D-glucopyranosyl-1]<sub>2</sub>β†’2)-<it>O</it>-Ξ±-D-xylopyranosyl-(1β†’2)-Ξ²-D-fructofuranoside (saccharide <b>3</b>).</p
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