The Effects of 8-Week Aerobic Training Program on Respiratory and Circulatory Parameters of Female Swimmers Between 12-14 Years Old

The purpose of this study is to investigate the effect of 8-week aerobic training program on respiratory and circulatory parameters in female swimmers between 12-14 years old. A total of 22 female swimmers, who were between 12-14 years old and joined to the national competitions in the province of Gaziantep, participated as volunteers. The subjects were randomly divided into two groups as experimental group (n=11, age:13.12±0.69) and control group (n=11, age:12.56±0.53). Aerobic training program was applied to the experimental group 3 days a week for 8 weeks. Both groups continued their regular swimming trainings. Resting heart rate (RHR), systolic blood pressure (SBP), diastolic blood pressure (DBP) measurements of the subjects were performed as circulatory parameters before and after training. These values were measured by Omron M6 Comfort device. Measurements of vital capacity (VC), forced vital capacity (FVC), forced expiratory volume (FEV1) and forced expiratory rate (FEV1/FVC) were performed as respiratory parameters. These values were measured by M.E.C. Pocket Spiro USB-100 instruments. For statistical analysis of data, Paired Sample t test was used for intra-group comparisons, and the Independent Sample t test was used for inter-group comparisons. The level of significance was determined as p0.05). The respiratory parameters of the control group were significant in FVC and FEV1 values (p0.05). As a result, it is thought that aerobic trainings have positive effects on respiratory and circulatory parameters in swimmers. It can be said that regular aerobic training improves respiratory and circulatory parameters

Re: Alpha-lipoic acid intoxication in an adolescent girl

[Abstract Not Available]WOS:0006242951000152-s2.0-85112490002PubMed: 3428633

Thrombosis risk of Alport syndrome patients: evaluation of cardiological, clinical, biochemical, genetic and possible causes of inherited thrombophilia and identification of a novel COL4A3 variant

To evaluate cases with Alport syndrome for laboratory, radiological, ophthalmological, auditory tests, cardiological and inherited thrombophilia risk. Laboratory findings, abdominal and urinary ultrasonography, ophthalmological and auditory tests and cardiological examination of 21 Alport syndrome suspicious cases were performed. Also, collagen type IV alpha three chain (COL4A3) gene, four chain (COL4A4) gene and five chain (COL4A5) genes were sequenced by next-generation sequencing system. In addition, possible causes of inherited thrombophilia were evaluated. A novel (c.2806C> T/p.Gln936Ter) variation in COL4A3 gene was detected in three cases. Also c.221G>A/p.Arg74Gln variation in COL4A5 gene of two cases, c.4421C>T/p.Thr1474Met variation in COL4A4 gene of one case, c.665C>T/p.Pro222Leu variation in COL4A4 gene of one case and compound heterozygous c.4421C>T/(p.Thr1474Met) and c.665C>T/p.Pro222Leu variation in COL4A4 gene of one case were detected. Although 10 (47.6%) cases had microscopic hematuria, six (28.6%) cases had macroscopic hematuria, but there were not hematuria in five (23.8%) of cases. Three cases with variation carrier in COL4A genes and one case without variation carrier had vision problem. Also, one case with variation carrier in COL4A gene had hearing loss. All cases with variation carrier in COL4A genes exclude one had at least one cardiac problems. Also, all cases with variation carrier in COL4A genes had possible causes of inherited thrombophilia risk. In addition to developing risk of progressive kidney failure, sensorineural hearing loss and ocular abnormalities, Alport syndrome cases may have increasing cardiac problems and possible causes of inherited thrombophilia risk. Therefore, these cases should be regularly evaluated and followed for cardiac problems and inherited thrombophilia risk. Copyright (C) 2020 Wolters Kluwer Health, Inc. All rights reserved.WOS:0006192843000052-s2.0-85084721849PubMed: 3233227

Methemoglobinemia after local anesthetic (prilocaine) application: a case report

Introduction: Circumcision is a surgical procedure performed by many societies for religious, medical and cultural purposes. One of the agents used during this procedure is prilocaine, a commonly used local anesthetic. In the literature, cases of methemoglobinemia which can be developed with the application of prilocaine in normal dose have been reported. Oxidation of hemoglobin with various oxidative stresses is called methemoglobinemia when the divalent iron in its content is converted into its trivalent form. This reaction leads to hypoxaemia in the tissue and a clinical picture of cyanosis occurs at varying degrees.Case Report: Two-and-a-half-month-old patient was referred to my hospital by a physician because of the complaint of bruising after local anesthesia with prilocaine and the measured oxygen saturation was 79%. Physical examination revealed cyanosis in the peroral region, hands and feet. It was decided that methylene blue should be administered considering the fact that the patient was given prilocaine as a local anesthetic, due to the inability to find an underlying respiratory and cardiac cause, and because of the high value of methemoglobin in blood gas. Methylene blue 2 mg/kg was given orally. About an hour later, cyanosis disappeared. The control methhemoglobin level was found to be 2.7%. Conclusion: Methemoglobinemia should be considered in the differential diagnosis of cyanosis after local anesthetic application and local anesthetics with less side effects should be preferred in early infancy. In this case report, it was aimed to discuss the differential diagnosis and treatment methods of methemoglobinemia after local anesthesia with prilocaine

Thrombotic thrombocytopenic purpura as a rare cause of anemia with thrombocytopenia in childhood: report of 2 cases

Thrombotic thrombocytopenic purpura (TTP) is a rare multisystem disorder characterized by single or recurrent episodes of thrombocytopenia, microangiopathic hemolytic anemia and widespread microvascular thrombosis, which causes significant morbidity and mortality unless promptly recognized and treated. The underlying pathogenesis is a defect in von Willebrand factor (vWF) cleaving protease, called "A Disintegrin and Metalloproteinase with Thrombospondin Type 1 Repeats 13 (ADAMTS-13)". There are 2 forms: congenital TTP (ADAMTS-13 gene mutations) and acquired TTP (autoantibodies and ADAMTS-13 deficiency). We presented two patients who initially presented with thrombotic microangiopathy and were later diagnosed with TTP upon demonstration of the deficiency in ADAMTS-13 activity

Transient sinus bradycardia caused by hepatitis A virus: a case report

Abstract Background The most common cause of acute viral hepatitis is the hepatitis A virus (HAV). Millions of people are thought to be infected each year. It is transmitted either by the fecal-oral route or by consuming contaminated food. Extrahepatic complications, notably cardiologic ones, are infrequent. This case report was presented due to the development of HAV-related bradycardia without hypotension in an unvaccinated refugee patient. Case presentation A 9-year-old male presented with the complaint of jaundice and vomiting. There was no history of fever, diarrhea, or abdominal pain. A precise knowledge of suspected food intake is lacking. There was no pathological examination finding except jaundice. Total bilirubin, direct bilirubin, aspartate aminotransferase, and alanine aminotransferase levels were high. The coagulation test was normal. Anti-HAV-IgM/IgG was positive in the patient with suspicious viral hepatitis. In the follow-up, the heart rate decreased to 43 beats/min during sleep and 46 beats/min when awake. Cardiological examination and tests were within normal limits. Hypotension was not accompanied. In the follow-up, bradycardia and impaired liver function tests regressed. The patient was discharged on the 10th day. Conclusions Cardiologic complications are rare, and patients diagnosed with acute hepatitis A should be monitored. The most effective way of protection from the hepatitis A virus is vaccination

Foreign Body Aspiration in Children; Duzce University Five-Years Results

Objective: Foreign body aspiration is a preventable cause of mortality and morbidity especially in younger than three years old children. The aim of this study is to determine the risk factors, causes and prognosis in patients with foreign body aspiration. Methods: In this study, laboratory and examination findings of 35 patients who underwent bronchoscopy, because of suspected foreign body aspiration, were retrospectively analyzed. Results: Of the 35 patients included in the study, 19 were boys and 16 were girls. The mean age was 3,2. The most causes of application were cough, and wheezing. Foreign body was detected in the right main bronchus in 62,8%, in the left main bronchus in 25,7%, in the trachea in 5,7% and in both bronchi in 5,7% of the patients. Conclusions: Early diagnosis and intervention significantly reduce the mortality and morbidity in foreign body aspirations. Prevention of foreign body aspirations is possible with the education of babysitters and family members.WOS:00070904020001

Recurrent wheezing in children: a tertiary care hospital data

Introduction: Repetitive wheezing in children today is an important problem. It is important to identify preventable risk factors in children with recurrent wheezing complaints. Asking for risk factors and making suggestions can prevent both recurrent admission and persistent bronchial damage. The present research was conducted to evaluate the risk factors of recurrent wheezing in children. Methods: This cross-sectional study was performed with 50 children with recurrent wheezing. Previous medical history and sociodemographic features of children were searched.Results: The 60%(n=30) of participants were male , %40 (n=20) were female. The mean age and birth weight of children were calculated 49.1 ± 48 months and 3227.2 ± 680.6 gr respectively. Children with recurrent wheezing had significantly diverse ratios in terms of the type of delivery (p=0,007), breast feding (p<0.001), vaccinations (p<0.001), atopic dermatitis (p<0.001), child care (p=0.003), natal and postnatal maternal smoking (p<0.001, p=0.007), asthma history of the parents and siblings (p<0.001), rural-urban settlement (p=0.021), and moisture and warming shape of family house (p=0.002). Conclusion: Recurrent wheezing is an important health problem in childhood.  Sociodemographic, environmental preventive approaches must be considered in the treatment modalities of patients

Recurrent wheezing in children: a tertiary care hospital data

Introduction: Repetitive wheezing in children today is an important problem. It is important to identify preventable risk factors in children with recurrent wheezing complaints. Asking for risk factors and making suggestions can prevent both recurrent admission and persistent bronchial damage. The present research was conducted to evaluate the risk factors of recurrent wheezing in children. Methods: This cross-sectional study was performed with 50 children with recurrent wheezing. Previous medical history and sociodemographic features of children were searched.Results: The 60%(n=30) of participants were male , %40 (n=20) were female. The mean age and birth weight of children were calculated 49.1 ± 48 months and 3227.2 ± 680.6 gr respectively. Children with recurrent wheezing had significantly diverse ratios in terms of the type of delivery (p=0,007), breast feding (p lt;0.001), vaccinations (p lt;0.001), atopic dermatitis (p lt;0.001), child care (p=0.003), natal and postnatal maternal smoking (p lt;0.001, p=0.007), asthma history of the parents and siblings (p lt;0.001), rural-urban settlement (p=0.021), and moisture and warming shape of family house (p=0.002). Conclusion: Recurrent wheezing is an important health problem in childhood.  Sociodemographic, environmental preventive approaches must be considered in the treatment modalities of patients

Attitude and behaviors of mothers regarding fever in children; a Duzce University Faculty of Medicine study

Introduction: In mothers with fever complaint who applied to Duzce University Faculty of Medicine Research and Practice Hostipal, defining attitude and behaviours and general knowledge levels about fever are aimed in this study.Methods: 230 patients who were admitted to pediatric emergency service and general pediatric outpatient clinics from February to June 2017 were included in the study. Questionnaires with 26 questions were evaluated in this study. Descriptive features, chi-square test and one-way ANOVA followed by Bonferroni’s post-hoc comparisons tests were performed in all statistical analyzes.Results: It was learned that 79.1% of the mothers were placing the thermometers under the armpit during measurement. Most of the mothers picked the normal body temperature as 35.5-36.4 ° C (57.8%). 74.8% of the mothers considered fever as a disease and 98.7% of the mothers thought that fever was harmful. Most of the mothers were considering the advices of doctors on reducing fever of children (48.7%). The most common intervention to reduce fever was to shower with warm water (73.5%). The most preferred antipyretic was paracetamol (76.1%). As the education levels increased, rates of showering with warm water and taking out the children's clothes were increasing significantly (p=0.027, p=0.025, respectively). Conclusion: In this study, it was seen that the mother's general knowledge about fever was inadequate and there were occasionally wrong attitudes and behaviors in order to reduce fever. We think that detailed information about fever given to the families by physicians will prevent unnecessary applications in this area