Book Review: Understanding and using educational theories

A book review on "Understanding and using educational theories" by Aubrey, K. and Riley, A. SAGE Publications, 2016, 216 pages. ISBN: 978-147390590

The perceptions of FE teachers about the impact of in-service initial teacher education on their professional development and practice

Since 1997, successive governments in England have consistently introduced a range of interventions aimed at developing the quality of training of FE teachers. It has been suggested that these should engender better teaching, which in turn should improve achievement of learners, and subsequently produce a workforce with global competitive advantage. This study explores and analyses the views of a sample of FE teachers and their managers on the impact of an in-service initial teacher education programme on teachers’ development and practice. The case study research uses online questionnaires and semi-structured interviews to collect data from participants drawn from both academic and vocational curriculum areas of a large FE college. The study employs Bourdieu’s concepts of habitus, field and capital and Giddens’ structuration framework of structure and agency to interpret and explain social practices and actions. Even though the past can frame agents’ dispositions, agents also have the capacity to accommodate and integrate new conditions in shaping future practices. An understanding of power relations within and between fields has been useful in explaining practitioners’ actions, and the concept of capital has been beneficial in analysing practitioners’ influence, and some factors that drive their actions. Initial findings from this study indicate that while structure can constrain agents’ actions, it can also be enabling. Although teachers have faced some constraints and challenges whilst on the training programme, there is a significant positive perception of the knowledge, skills and competencies that they have acquired. Findings also indicate that the social-cultural construction of knowledge approach and teachers’ own passion are significant to their professional development. The thesis proposes a case for reflexive breakout, a phrase used to portray the transformative capacity of teachers in developing their professional practice. This perhaps has some implications for further research in understanding the professional development of trainee teachers

Investigations into the spatial distribution of γH2AX around a DNA double-strand break and the analysis of double-strand break mobility

A hallmark of the cellular response to DNA double-strand breaks (DSBs) is histone H2AX phosphorylation by the protein kinase ATM. H2AX is unevenly distributed throughout chromatin and is rapidly phosphorylated to form γH2AX up to 2 megabases either side of DSBs. Studies in yeast systems have shown that while γH2A can spread in cis surrounding the break site, it can also spread in trans onto unbroken chromosomes located in close spatial proximity. Although the majority of data in the current literature presents the well characterised in cis spread of γH2AX, there are strong indications that it can also occur in trans in mammalian systems; analogous to the findings shown in yeast. This thesis lays out the steps taken to develop a novel system to address the spatial distribution of γH2AX around a nascent DSB. Since the first published live imaging experiments of the dynamics of chromatin by in vivo single particle tracking there has been extensive investigation into the regulation and biological function of movement of damaged DNA. In yeast, a relative consensus exists that DSB induction increases the movement of a DSB. In contrast to yeast however, data published of DSB movement in higher eukaryotes has been controversial, caused by conflicting results. Here, I developed a cell-based system, and utilised timelapse live cell imaging to show that a chromosomal locus containing a single endonuclease-induced DSB shows confined movement in comparison to an undamaged locus. Furthermore, this confined movement of a damaged locus is compounded by treatment with an ATM kinase inhibitor but not a DNA-PKcs kinase inhibitor, suggesting that the kinase activity of ATM and not the kinase activity of DNA-PKcs plays a significant role in the dynamics of DSBs

Pattern of seat belt use by drivers in Trinidad and Tobago, West Indies

<p>Abstract</p> <p>Background</p> <p>In Trinidad and Tobago, the law on the mandatory use of seat belts was passed in 1995, but this law is hardly enforced. The objective of this study was to determine the frequency and predictors of seat belt use by motor vehicle drivers in the country.</p> <p>Findings</p> <p>A cross-sectional study of 959 motor vehicle drivers using a self-administered questionnaire. Data analysis included Pearson Chi square test and multinomial logistic regression analysis in order to determine the possible predictors of seat belt use by the drivers in Trinidad and Tobago. A majority of the drivers sometimes (51.8%) or always (31.6%) use a seat belt. About 16.7%, 29% and 54.2% of the drivers perceived that the other drivers use their seat belts more frequently, with the same frequency and less frequently respectively compared to themselves. The main reason for not using seat belt by the drivers was given as frequent stops (40.7%) and the main motivation to use seat belt by the drivers was given as stiffer penalties for non-compliance with the seat belt law (44.5%). The predictors of seat belt use were male driver, no formal or lower level of education, driving for less than 10 years, and the perception that the other drivers use seat belts with the same or higher frequency compared to the respondents.</p> <p>Conclusion</p> <p>Only a small proportion of the drivers in Trinidad and Tobago always use a seat belt when driving. There is the need to enforce the seat belt legislation in the country.</p

Overweight, obesity and underweight in nurses in Vhembe and Capricorn districts, Limpopo

Background: In South Africa, anecdotal evidence concerning the prevalence of overweight and obesity in nurses is alarming, but no scientific studies have confirmed this notion. This study aimed to determine the prevalence of underweight, overweight and obesity in black nurses practising in South Africa.Method: A cross-sectional study involving 153 nurses, aged 19-50 years and older, was undertaken in the Vhembe and Capricorn districts, Limpopo province. Height and weight were measured to determine body mass index (BMI) and physical activity was assessed by report. The World Health Organization criteria determined the BMI categories.Results: The mean BMI of the nurses was 31.7 ± 18.1 kg/m2. The prevalence of underweight, overweight, obesity and extreme obesity in the nurses was 2%, 27.5%, 44.4% and 7.2%, respectively. The prevalence of overweight and obesity increased with age, peaking at ages 30-39 for overweight, and over 50 years of age for obesity. Among the males nurses, the prevalence of underweight, overweight, obesity and extreme obesity were 2%, 30.6%, 36.7% and 6.1%, respectively. Corresponding figures for the female nurses were 1.9%, 26%, 48.1% and 7.7%, respectively.Conclusion: The study revealed a high prevalence of overweight and obesity in nurses in the Vhembe and Capricorn districts, a rate that is comparable with that of the general population in South Africa. Future studies are needed to identify risk factors for the prevalence of overweight and obesity in nurses.Keywords: nurses, body mass index, overweight, obesity, underweight, South Afric

Another string to the polo bow: a new mitotic role of PLK1 in centromere protection

Polo-like kinase 1 (PLK1) plays a fundamental role in the spatiotemporal control of mitosis. Cells lacking PLK1 activity exhibit characteristic chromosome misalignment due to defects in microtubule-kinetochore organization and attachment. In our recently published paper, we uncover a new role for PLK1 in the preservation and maintenance of centromere integrity

Prevalence of malnutrition and vitamin A deficiency in Nigerian preschool children subsisting on high intakes of carotenes

The prevalence of malnutrition and vitamin A deficiency was determined in 204 preschool children of both sexes aged 3–57 months. The children were recruited from 2 rural communities of Atakumosa Local Government Area of Osun State in South West Nigeria. Dietary vitamin A intake was estimated from frequency of consumption of locally available vitamin A containing food items. Vitamin A status of the children was assessed from concentration of retinol in plasma. Nutritional status was assessed from height and weight compared with international reference standards. The results indicate widespread malnutrition among the children. The prevalence of stunting (low height for age) was 60.8% while prevalence of wasting (low weight for height) was 7.4% and of underweight (low weight for age) 27.5%. Dietary vitamin A intake appeared to be adequate in the children. Intake of vitamin A is predominantly from plant sources. At least 43% of the children consumed the carotene rich red palm oil 6 or more times per week in contrast to less than 1% who consumed eggs or milk for 6 or more times per week. Vitamin A deficiency was low in the children. Only 11.3% of the children had plasma retinol concentration <0.70µmol/L. The results indicate that childhood malnutrition of public health magnitude can coexist with adequate dietary vitamin A intakes or vitamin A status

The burden of road traffic crashes, injuries and deaths in Africa:A systematic review and meta-analysis

Objective To estimate the burden of road traffic injuries and deaths for all road users and among different road user groups in Africa. Methods We searched MEDLINE, EMBASE, Global Health, Google Scholar, websites of African road safety agencies and organizations for registry- and population-based studies and reports on road traffic injury and death estimates in Africa, published between 1980 and 2015. Available data for all road users and by road user group were extracted and analysed. We conducted a random-effects meta-analysis and estimated pooled rates of road traffic injuries and deaths. Findings We identified 39 studies from 15 African countries. The estimated pooled rate for road traffic injury was 65.2 per 100000 population (95% confidence interval, CI: 60.8–69.5) and the death rate was 16.6 per 100 000 population (95% CI: 15.2–18.0). Road traffic injury rates increased from 40.7 per 100 000 population in the 1990s to 92.9 per 100 000 population between 2010 and 2015, while death rates decreased from 19.9 per 100 000 population in the 1990s to 9.3 per 100 000 population between 2010 and 2015. The highest road traffic death rate was among motorized four-wheeler occupants at 5.9 per 100 000 population (95% CI: 4.4–7.4), closely followed by pedestrians at 3.4 per 100 000 population (95% CI: 2.5–4.2). Conclusion The burden of road traffic injury and death is high in Africa. Since registry-based reports underestimate the burden, a systematic collation of road traffic injury and death data is needed to determine the true burden

DNA replication is highly resilient and persistent under the challenge of mild replication stress

Mitotic DNA synthesis (MiDAS) has been proposed to restart DNA synthesis during mitosis because of replication fork stalling in late interphase caused by mild replication stress (RS). Contrary to this proposal, we find that cells exposed to mild RS in fact maintain continued DNA replication throughout G2 and during G2-M transition in RAD51- and RAD52-dependent manners. Persistent DNA synthesis is necessary to resolve replication intermediates accumulated in G2 and disengage an ATR-imposed block to mitotic entry. Because of its continual nature, DNA synthesis at very late replication sites can overlap with chromosome condensation, generating the phenomenon of mitotic DNA synthesis. Unexpectedly, we find that the commonly used CDK1 inhibitor RO3306 interferes with replication to preclude detection of G2 DNA synthesis, leading to the impression of a mitosis-driven response. Our study reveals the importance of persistent DNA replication and checkpoint control to lessen the risk for severe genome under-replication under mild RS