Proposal of low-cost housing modules for families of the socioeconomic level 'D': cCse study Arequipa-La Joya Project

This research work is aimed at developing a real estate project of an urbanization formed by single-family housing modules, located in a peri-urban area of the district of La Joya, province and region Arequipa. The property is characterized by having great potential due to the opportunity cost of the land price, which allows to carry out a project of this type. In recent years, in the sector, it has been giving urban habilitations destined, in its entirety, to houses of country for the socioeconomic levels A and B, bypassing to families of the socioeconomic level D; For this reason the project represents an interesting proposal by not having competition in the supply of the sector. This will begin with the urban habilitation of a field of 40896.00 m², resulting in a useful area of 25056.00 m², distributed in 261 lots of 96.00 m². In each of these lots a basic single-family housing module of 38.29 m² of covered area will be built. It also includes a market study that will mark the guidelines for the definition of the product appropriate to the preferences and needs of the target customer. The market study, even, presents an interesting deficit between the supply and demand of this type of housing in the population of the city of Arequipa, which is hoax by the project. The work also includes an analysis of different constructive systems taking into account the following indicators: efficiency, efficiency, market and regulation. Project planning is done by taking Lean Construction tools to ensure deadlines. The work culminates in a cash flow, which reflects, in its indicators, the academic appeal of the project for potential investors.Trabajo de investigaciónEl presente trabajo de investigación está orientado a desarrollar un proyecto inmobiliario de una urbanización conformada por módulos de vivienda unifamiliares, ubicada en una zona periurbana del distrito de La Joya, provincia de Arequipa. El predio se caracteriza por tener un gran potencial debido al costo oportunidad del precio del terreno, que permite realizar un proyecto de este tipo. En años recientes, en el sector, se ha venido dando habilitaciones urbanas destinadas, en su totalidad, a casas de campo para los niveles socioeconómicos A y B, soslayando a familias del nivel socioeconómico D; por esta razón el proyecto representa una interesante propuesta al no contar con competencia en la oferta del sector. Este se iniciará con la habilitación urbana de un terreno de 40 896.00 m², teniendo como resultado un área útil de 25 056.00 m², distribuidos en 261 lotes de 96.00 m². En cada uno de estos lotes se edificará un módulo de vivienda unifamiliar básico de 38.29 m² de área techada. Asimismo, comprende un estudio de mercado que marcará las pautas para la definición del producto adecuado a las preferencias y necesidades del cliente objetivo. El estudio de mercado, incluso, presenta un interesante déficit entre la oferta y demanda de este tipo de vivienda en la población de la ciudad de Arequipa, el cual es redituado por el proyecto. El trabajo incluye, además, un análisis de diferentes sistemas constructivos teniendo en cuenta los siguientes indicadores: eficiencia, eficacia, mercado y normatividad. El planeamiento del proyecto se realiza tomando herramientas de Lean Construction para asegurar el cumplimiento de plazos. El trabajo culmina con un flujo de caja, el cual refleja, en sus indicadores, el atractivo académico del proyecto para potenciales inversionistas

High PEEP with recruitment maneuvers versus Low PEEP During General Anesthesia for Surgery -a Bayesian individual patient data meta-analysis of three randomized clinical trials

Background: The influence of high positive end-expiratory pressure (PEEP) with recruitment maneuvers on the occurrence of postoperative pulmonary complications after surgery is still not definitively established. Bayesian analysis can help to gain further insights from the available data and provide a probabilistic framework that is easier to interpret. Our objective was to estimate the posterior probability that the use of high PEEP with recruitment maneuvers is associated with reduced postoperative pulmonary complications in patients with intermediate-to-high risk under neutral, pessimistic, and optimistic expectations regarding the treatment effect. Methods: Multilevel Bayesian logistic regression analysis on individual patient data from three randomized clinical trials carried out on surgical patients at Intermediate-to-High Risk for postoperative pulmonary complications. The main outcome was the occurrence of postoperative pulmonary complications in the early postoperative period. We studied the effect of high PEEP with recruitment maneuvers versus Low PEEP Ventilation. Priors were chosen to reflect neutral, pessimistic, and optimistic expectations of the treatment effect. Results: Using a neutral, pessimistic, or optimistic prior, the posterior mean odds ratio (OR) for High PEEP with recruitment maneuvers compared to Low PEEP was 0.85 (95% Credible Interval [CrI] 0.71 to 1.02), 0.87 (0.72 to 1.04), and 0.86 (0.71 to 1.02), respectively. Regardless of prior beliefs, the posterior probability of experiencing a beneficial effect exceeded 90%. Subgroup analysis indicated a more pronounced effect in patients who underwent laparoscopy (OR: 0.67 [0.50 to 0.87]) and those at high risk for PPCs (OR: 0.80 [0.53 to 1.13]). Sensitivity analysis, considering severe postoperative pulmonary complications only or applying a different heterogeneity prior, yielded consistent results. Conclusion: High PEEP with recruitment maneuvers demonstrated a moderate reduction in the probability of PPC occurrence, with a high posterior probability of benefit observed consistently across various prior beliefs, particularly among patients who underwent laparoscopy