ЛИЧНОСТЬ ЗАСЛУЖЕННОГО ПРОФЕССОРА Н. С. БОКАРИУСА В ОТЗЫВАХ ЕГО ЗАРУБЕЖНЫХ СОВРЕМЕННИКОВ

The article is dedicated to the 85th anniversary of the death of outstanding scientist Nikolai Sergeevich Bokarius. Emphasis is placed on given references of contemporaries, pupils, and followers about N. S. Bokarius, in which they appreciated his outstanding scientific, pedagogical and organizational talents. The article contains original texts of obituaries placed in foreign specialized scientific journals in memory of the unique personality of N. S. Bokarius.Присвячено 85-річчю від дня смерті видатного вченого Миколи Сергійовича Бокариуса. Наведено відгуки сучасників, учнів, послідовників про М. С. Бокариуса, які гідно оцінили його видатний науковий, педагогічний і організаторський таланти. Подано оригінальні тексти некрологів у пам’ять унікальної особистості М. С. Бокаріуса в зарубіжних профільних наукових журналах

Study of gas hazard pattern in underground workings after blasting

Determining the sources of hazardous and toxic substances released into mine air, their gas composition, as well as providing each such source of pollution with the required amount of fresh air are important issues in terms of ensuring normal healthy and safe working conditions for miners. This paper studies blasting as one of the most dangerous sources of mine air pollution. The study was carried out for a long dead-end exploration working, and a development (preparatory) working of a copper-nickel mine. In accordance with the federal rules and regulations (FNiP), a number of requirements, including monitoring of gas hazard at a face, is applied to blasting operations. The study examined the behavior of gas-air mixture in dead-end mine workings after blasting. The findings are based on the experimental data obtained in the conditions of two dead-end workings at an operating coppernickel mine. A technique for the experimental studies of gas release after blasting in a dead-end working was developed. The main technical characteristics of the instruments involved in the in-situ measurements are given. Time dependences of the concentrations of toxic gases after blasting at the blasted working mouth, at the return ventilation current, and near a booster were established. In order to assess the reliability of the data obtained, the volume of released carbon oxides was calculated based on the data of gas analyzers and chemical reactions of explosives decomposition during detonation, depending on the types and weights of the explosives. A model of gas-air mixture transfer was described, constructed, and calibrated allowing for longitudinal dispersion. The Voronin model was used to simulate the gradual removal of toxic gases from the working face and solving the problem of boundary conditions. Based on experimental data, the coefficients of longitudinal dispersion, ventilation efficiency, and volume concentration of the considered gas admixture in the mixing zone at initial time were determined for a long dead-end mine working. The constructed gas-dynamic model and longitudinal dispersion coefficients obtained as a result of the analysis enabled the time required for long dead-end mine workings ventilation to be analysed and estimated. Based on the model, the algorithm for calculating the velocity of spreading the combustion products in a mine ventilation network in emergency situations is being improved. The value of longitudinal dispersion coefficient for different operating conditions is also being refined. Based on the gas distribution simulation within the interval of 1,500 m from a working face, the time required for the ventilation of a dead-end mine working was determined

Cholinesterase in different types of the muscle tissue during the early postmortem period for diagnosis of death coming

The purpose of the research: consisted in study of postmortem regularitiesin the content of cholinesterase in different types of muscle tissue (MT) for improving accuracy of determination of the prescription of death coming PDC.Materials and methods: The activity/level of cholinesterase was determined in homogenates of the myocardial (MMH), oesophageal (OMH), diaphragm (DMH) and intercostal muscles (IMH)within the early PMP (3-13 hours after the coming of death) on 30 human corpses. MT was sampled in conditions of postmortem biopsy with use of special instruments; MT homogenates were prepared following the standard technique with subsequent determination of cholinesterase content in MT homogenates. Results and discussion: The analysis of postmortem changes in the content of cholinesterase in MT depending upon PDC revealed that after 3 hours from the moment of death coming its highest content was in muscles of the oesophagus, the least one being in MT of the intercostal muscles (respectively, (2,717.1±37.1) and (883.5±6.2) U/g, р<0.001). Levels of cholinesterase content in MT of the myocardium and diaphragm were rather close, though they differed (respectively, (1,213.8±8.8) and (1,512.8±11.5) U/g, р<0.05), and occupied an intermediate place between the corresponding values of MT of the intercostal muscles and oesophagus.A common pattern for the content of cholinesterase in different types of MT was characterized by a decrease of this content with an increase in PDC terms; besides, the dynamic lines of its changes, that we obtained, became basic ones for substantiating quantitative time dependencies and construction of relevant nomograms for forensic diagnosis of PDC by cholinesterase content in MT. Conclusions: It was proved that the content of cholinesterase in all MT homogenates, which we studied, changed regularly (and nonlinearly), but the initial and final levels of cholinesterase content differed depending upon the type of MT. Besides, the dynamics in changes of the content of cholinesterase within the time period of 3÷13 hours from the moment of death coming differed upon the type of MT too. Advantages of the technique consist in theintegrity of biochemical examination of different types of MT and simplicity in interpretation of findings. The application of the nomogram technique for assessing PDC by cholinesterase content in MT makes it possible to improve the accuracy of diagnosis for terms of the coming of death up to 60 minutes

СУДОВО-МЕДИЧНА ОЦІНКА ТРАВМ ШИЙНОГО ВІДДІЛУ ХРЕБТА З УРАХУВАННЯМ ЗМІН ЦЕНТРАЛЬНОЇ ГЕМОДИНАМТКИ

The article analyzes the up-to-date state and problematic issues of forensic medical diagnosis of cervical spine injuries. It establishes that there are cases when forensic medical experts underestimate the outcomes and consequences of this trauma. It studies the state of the central hemodynamics of the injured with cervical spine traumas. At the same time 107 injured were divided into two groups: with clear and moderate manifestations. The research applied an objective and modern method of Doppler echocardiography. The conducted research has demonstrated significant changes in extraand intracerebral blood flow. The results of the comparative analysis show that forensic medical assessment of cervical spine traumas should take into account the results of Doppler echocardiography. Among these results the most informative are functional changes of the cerebral and spinal arteries. The manifestation of these deviations is determined, primarily, by the severity and time of injuries. The article determines the ways of improving forensic medical examinations of the injured with cervical spine traumas. It demonstrates the criteria significance of changes in bloodflow of cerebral and cervical arteries of the injured while establishing the severity of injuries.Досліджено стан центральної гемодинаміки в постраждалих із травмами шийного відділу хребта. За результатами порівняльного аналізу доведено, що судово-медична оцінка травм шийного відділу хребта має враховувати допплерографічні показники, серед яких найбільш інформативними є функціональні зміни загальної мозкової й хребцевої артерій

The Investigation of Ancient Sanctuaries of the Aral and Caspian Steppes: some Results and Perspectives

In the frame of an European INTAS (International Association for the Promotion of Cooperation with Scientists from the New Independent States of the Former Soviet Union) Project RFBR 95-336 sponsored by the Institute of Archaeology of Academy of Sciences of Russia with the title Research of the ancient Sanctuaries of the Aral-Caspian region: Reconstruction of the ethno-cultural and sociopolitical History of the Steppe Nomads, 1st millennium BC, the author together with his partners is dealing with special burial finds of the Schythian period and in particular with burial stone with human figurative representation of Scythian period

ЭКОНОМИЧЕСКИЕ НАУКИ РОЛЬ ПЛАТЕЖНО-РАСЧЕТНЫХ СИСТЕМ В ОБЕСПЕЧЕНИИ СТАБИЛЬНОСТИ И РАЗВИТИЯ РЫНКА ФИНАНСОВЫХ УСЛУГ ROLE OF PAYMENT AND SETTLEMENT SYSTEMS IN ENSURING STABILITY AND MARKET DEVELOPMENT OF FINANCIAL SERVICES

В современном мире вследствие активного развития финансовых услуг особое значение приобрета-ют платежные системы. В настоящей статье рассматривается глобальный характер возросшей значимости платежных систем в обеспечении финансовой стабильности. Сделан вывод о том, что платежные системы могут быть усиливающим фактором в развитии негативного влияния на все финансовые процессы. Глоба-лизация мирового финансового рынка диктует необходимость взаимодействия национальных платежных систем, вследствие чего возникает требование интегрируемости финансовой инфраструктуры рынка как внутри стран, так и при взаимодействии с аналогичными системами других стран. Проанализирована взаи-мозависимая природа различных платежных систем. Усиливающиеся взаимосвязи платежных систем при-обретают противоположный характер. С одной стороны, техническая стандартизация и интеграция между системами способствует автоматизации процессов, что позволяет снизить операционные риски. С другой стороны, взаимозависимости систем могут привести к распространению сбоев на всю финансовую инфра-структуру рынка. Ключевые слова: платежная система, финансовая стабильность, платежный кризис ROLE OF PAYMENT AND SETTLEMENT SYSTEMS IN ENSURING STABILITY AND MARKET DEVELOPMENT OF FINANCIAL SERVICES Olkhovskiy V.A., Galimova G.A. The Bashkir State University, Ufa, In the world today the payment systems are particularly important due to the active development of the fi nancial services. We can say that they have an impact on the functioning of fi nancial markets and affect the management of economy. The global increased importance of payment systems and fi nancial stability are considered in this article. In conclusion that payment systems are able to have a negative impact an all fi nancial processes. Globalization of the world fi nancial market dictates need of interaction of national payment systems. So there is a requirement of integrability of a fi nancial infrastructure of the market both in the countries, and in case of interaction with payment systems of other countries. The analysis of the interdependent nature of various payment systems is carried out. Amplifying interrelations of payment systems have opposite nature. On the one hand, technical standardization and integration promotes automation of processes, reduces operational risks. On the other hand, interdependence can lead to distribution of failures on all fi nancial infrastructure of the market

Significance of the XRCC1 gene Arg399Gln polymorphism in the pathogenesis of the chronic myeloproliferative diseases

Текст статьи не публикуется в открытом доступе в соответствии с политикой журнала.We investigated the association between Arg399Gln polymorphism in DNA repair gene XRCC1 and chronic myeloproliferative diseases. 79 patients with chronic myeloid leukemia (CML), 91 patient with polycythemia vera (PV), 132 patients with essential thrombocythemia (ET). 50 patients with myelofibrosis and 114 controls were included in the study. We genotyped the polymorphism in XRCC1 gene by using polymerase chain reaction in real-time with TaqMan assay. The detection and quantification of the JAK2 gene V617F mutation allele burden was carried out by means of "Pyromark q24" pyrosequencing. The presence of at least one XRCC1 399Gln allele was found to be significantly different in patients with CML (OR 1.53; 95% CI 0.67-3.51) and ET (OR 1.31; 95% CI 0.61-2.78) in comparison with controls. The presence of XRCC1 399Gln allele was associated with the resistance to imatinib. We found no interactions between the XRCC1 genotype and the level JAK2 allelic burden. These data suggest about a significance of the XRCC1 gene product in the control of precursor cells of the myeloid differentiation in CML and ET cells. Testing Arg399Gln polymorphism in XRCC1 gene may be useful for the assessment of the prognosis and treatment efficacy

Significance of the XRCC1 gene Arg399Gln polymorphism in the pathogenesis of the chronic myeloproliferative diseases

Текст статьи не публикуется в открытом доступе в соответствии с политикой журнала.We investigated the association between Arg399Gln polymorphism in DNA repair gene XRCC1 and chronic myeloproliferative diseases. 79 patients with chronic myeloid leukemia (CML), 91 patient with polycythemia vera (PV), 132 patients with essential thrombocythemia (ET). 50 patients with myelofibrosis and 114 controls were included in the study. We genotyped the polymorphism in XRCC1 gene by using polymerase chain reaction in real-time with TaqMan assay. The detection and quantification of the JAK2 gene V617F mutation allele burden was carried out by means of "Pyromark q24" pyrosequencing. The presence of at least one XRCC1 399Gln allele was found to be significantly different in patients with CML (OR 1.53; 95% CI 0.67-3.51) and ET (OR 1.31; 95% CI 0.61-2.78) in comparison with controls. The presence of XRCC1 399Gln allele was associated with the resistance to imatinib. We found no interactions between the XRCC1 genotype and the level JAK2 allelic burden. These data suggest about a significance of the XRCC1 gene product in the control of precursor cells of the myeloid differentiation in CML and ET cells. Testing Arg399Gln polymorphism in XRCC1 gene may be useful for the assessment of the prognosis and treatment efficacy