27,995 research outputs found
Scalar models for the unification of the dark sector
We review the difficulties of the generalized Chaplygin gas model to fit
observational data, due to the tension between background and perturbative
tests. We argue that such issues may be circumvented by means of a
self-interacting scalar field representation of the model. However, this
proposal seems to be successful only if the self-interacting scalar field has a
non-canonical form. The latter can be implemented in Rastall's theory of
gravity.Comment: Latex file, 8 pages, 3 figures in eps format. To appear in the
proceedings of the CosmoSul conference, held in Rio de Janeiro, Brazil, 01-05
august of 201
Radar backscattering data for surfaces of geological interest
Radar backscattering data for surfaces of geological interes
Assessing functional novelty of PSI structures via structure-function analysis of large and diverse superfamilies
The structural genomics initiatives have had as one of their aims to improve our understanding of protein function by providing representative structures for many structurally uncharacterised protein families. As suggested by the recent assessment of the Protein Structure Initiative (Structural Genomics Initiative, funded by the NIH), doubts have arisen as to whether Structural Genomics as initially planned were really beneficial to our understanding of biological issues, and in particular of protein function.
A few protein domain superfamilies have been shown to account for unexpectedly large numbers of proteins encoded in fully sequenced genomes. These large superfamilies are generally very diverse, spanning a wide range of functions, both in terms of molecular activities and biological processes. Some of these superfamilies, such as the Rossmann-fold P-loop nucleotide hydrolases or the TIM-barrel glycosidases, have been the subject of extensive structural studies which in turn have shed light on how evolution of the sequence and structure properties produce functional diversity amongst homologues. Recently, the Structure-Function Linkage Database (SFLD) has been setup with the aim of helping the study of structure-function correlations in such superfamilies. Since the evolutionary success of these large superfamilies suggests biological importance, several Structural Genomics Centers have focused on providing full structural coverage for representatives of all sequence families in these superfamilies.
In this work we evaluate structure/function diversity in a set of these large superfamilies and attempt to assess the quality and quantity of biological information gained from Structural Genomics.

Rastall Cosmology and the \Lambda CDM Model
Rastall's theory is based on the non-conservation of the energy-momentum
tensor. We show that, in this theory, if we introduce a two-fluid model, one
component representing vacuum energy whereas the other pressureless matter
(e.g. baryons plus cold dark matter), the cosmological scenario is the same as
for the \Lambda CDM model, both at background and linear perturbative levels,
except for one aspect: now dark energy may cluster. We speculate that this can
lead to a possibility of distinguishing the models at the non-linear
perturbative level.Comment: 9 pages, 1 figure. Accepted for publication in Physical Review
Metabolic regulation by p53 family members
The function of p53 is best understood in response to genotoxic stress, but increasing evidence suggests that p53 also plays a key role in the regulation of metabolic homeostasis. p53 and its family members directly influence various metabolic pathways, enabling cells to respond to metabolic stress. These functions are likely to be important for restraining the development of cancer but could also have a profound effect on the development of metabolic diseases, including diabetes. A better understanding of the metabolic functions of p53 family members may aid in the identification of therapeutic targets and reveal novel uses for p53-modulating drugs
A new class of entanglement measures
We introduce new entanglement measures on the set of density operators on
tensor product Hilbert spaces. These measures are based on the greatest cross
norm on the tensor product of the sets of trace class operators on Hilbert
space. We show that they satisfy the basic requirements on entanglement
measures discussed in the literature, including convexity, invariance under
local unitary operations and non-increase under local quantum operations and
classical communication.Comment: Revised version accepted by J Math Phys, 12 pages, LaTeX, contains
Sections 1-5 & 7 of the previous version. The previous Section 6 is now in
quant-ph/0105104 and the previous Section 8 is superseded by quant-ph/010501
Quantifying nonorthogonality
An exploratory approach to the possibility of analyzing nonorthogonality as a
quantifiable property is presented. Three different measures for the
nonorthogonality of pure states are introduced, and one of these measures is
extended to single-particle density matrices using methods that are similar to
recently introduced techniques for quantifying entanglement. Several
interesting special cases are considered. It is pointed out that a measure of
nonorthogonality can meaningfully be associated with a single mixed quantum
state. It is then shown how nonorthogonality can be unlocked with classical
information; this analysis reveals interesting inequalities and points to a
number of connections between nonorthogonality and entanglement.Comment: Accepted for publication in Phys. Rev.
Recommended from our members
The importance of including habitat-specific behaviour in models of butterfly movement
Dispersal is a key process affecting population persistence and major factors affecting dispersal rates are the amounts, connectedness and properties of habitats in landscapes. We present new data on the butterfly Maniola jurtina in flower-rich and flower-poor habitats that demonstrates how movement and behaviour differ between sexes and habitat types, and how this effects consequent dispersal rates. Females had higher flight speeds than males but their total time in flight was four times less. The effect of habitat type was strong for both sexes, flight speeds were ~2.5x and ~1.7x faster on resource-poor habitats for males and females respectively, and flights were approximately 50% longer. With few exceptions females oviposited in the mown grass habitat, likely because growing grass offers better food for emerging caterpillars, but they foraged in the resource-rich habitat. It seems that females faced a trade-off between ovipositing without foraging in the mown grass or foraging without ovipositing where flowers were abundant. We show that taking account of habitat-dependent differences in activity, here categorised as flight or non-flight, is crucial to obtaining good fits of an individual-based model to observed movement. An important implication of this finding is that incorporating habitat-specific activity budgets is likely necessary for predicting longer-term dispersal in heterogeneous habitats as habitat-specific behaviour substantially influences the mean (>30% difference) and kurtosis (1.4x difference) of dispersal kernels. The presented IBMs provide a simple method to explicitly incorporate known activity and movement rates when predicting dispersal in changing and heterogeneous landscapes
Semiclassical states for quantum cosmology
In a metric variable based Hamiltonian quantization, we give a prescription
for constructing semiclassical matter-geometry states for homogeneous and
isotropic cosmological models. These "collective" states arise as infinite
linear combinations of fundamental excitations in an unconventional "polymer"
quantization. They satisfy a number of properties characteristic of
semiclassicality, such as peaking on classical phase space configurations. We
describe how these states can be used to determine quantum corrections to the
classical evolution equations, and to compute the initial state of the universe
by a backward time evolution.Comment: 13 page
- …