27,995 research outputs found

    Scalar models for the unification of the dark sector

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    We review the difficulties of the generalized Chaplygin gas model to fit observational data, due to the tension between background and perturbative tests. We argue that such issues may be circumvented by means of a self-interacting scalar field representation of the model. However, this proposal seems to be successful only if the self-interacting scalar field has a non-canonical form. The latter can be implemented in Rastall's theory of gravity.Comment: Latex file, 8 pages, 3 figures in eps format. To appear in the proceedings of the CosmoSul conference, held in Rio de Janeiro, Brazil, 01-05 august of 201

    Radar backscattering data for surfaces of geological interest

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    Radar backscattering data for surfaces of geological interes

    Assessing functional novelty of PSI structures via structure-function analysis of large and diverse superfamilies

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    The structural genomics initiatives have had as one of their aims to improve our understanding of protein function by providing representative structures for many structurally uncharacterised protein families. As suggested by the recent assessment of the Protein Structure Initiative (Structural Genomics Initiative, funded by the NIH), doubts have arisen as to whether Structural Genomics as initially planned were really beneficial to our understanding of biological issues, and in particular of protein function.
A few protein domain superfamilies have been shown to account for unexpectedly large numbers of proteins encoded in fully sequenced genomes. These large superfamilies are generally very diverse, spanning a wide range of functions, both in terms of molecular activities and biological processes. Some of these superfamilies, such as the Rossmann-fold P-loop nucleotide hydrolases or the TIM-barrel glycosidases, have been the subject of extensive structural studies which in turn have shed light on how evolution of the sequence and structure properties produce functional diversity amongst homologues. Recently, the Structure-Function Linkage Database (SFLD) has been setup with the aim of helping the study of structure-function correlations in such superfamilies. Since the evolutionary success of these large superfamilies suggests biological importance, several Structural Genomics Centers have focused on providing full structural coverage for representatives of all sequence families in these superfamilies.
In this work we evaluate structure/function diversity in a set of these large superfamilies and attempt to assess the quality and quantity of biological information gained from Structural Genomics.
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    Rastall Cosmology and the \Lambda CDM Model

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    Rastall's theory is based on the non-conservation of the energy-momentum tensor. We show that, in this theory, if we introduce a two-fluid model, one component representing vacuum energy whereas the other pressureless matter (e.g. baryons plus cold dark matter), the cosmological scenario is the same as for the \Lambda CDM model, both at background and linear perturbative levels, except for one aspect: now dark energy may cluster. We speculate that this can lead to a possibility of distinguishing the models at the non-linear perturbative level.Comment: 9 pages, 1 figure. Accepted for publication in Physical Review

    Metabolic regulation by p53 family members

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    The function of p53 is best understood in response to genotoxic stress, but increasing evidence suggests that p53 also plays a key role in the regulation of metabolic homeostasis. p53 and its family members directly influence various metabolic pathways, enabling cells to respond to metabolic stress. These functions are likely to be important for restraining the development of cancer but could also have a profound effect on the development of metabolic diseases, including diabetes. A better understanding of the metabolic functions of p53 family members may aid in the identification of therapeutic targets and reveal novel uses for p53-modulating drugs

    A new class of entanglement measures

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    We introduce new entanglement measures on the set of density operators on tensor product Hilbert spaces. These measures are based on the greatest cross norm on the tensor product of the sets of trace class operators on Hilbert space. We show that they satisfy the basic requirements on entanglement measures discussed in the literature, including convexity, invariance under local unitary operations and non-increase under local quantum operations and classical communication.Comment: Revised version accepted by J Math Phys, 12 pages, LaTeX, contains Sections 1-5 & 7 of the previous version. The previous Section 6 is now in quant-ph/0105104 and the previous Section 8 is superseded by quant-ph/010501

    Quantifying nonorthogonality

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    An exploratory approach to the possibility of analyzing nonorthogonality as a quantifiable property is presented. Three different measures for the nonorthogonality of pure states are introduced, and one of these measures is extended to single-particle density matrices using methods that are similar to recently introduced techniques for quantifying entanglement. Several interesting special cases are considered. It is pointed out that a measure of nonorthogonality can meaningfully be associated with a single mixed quantum state. It is then shown how nonorthogonality can be unlocked with classical information; this analysis reveals interesting inequalities and points to a number of connections between nonorthogonality and entanglement.Comment: Accepted for publication in Phys. Rev.

    Semiclassical states for quantum cosmology

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    In a metric variable based Hamiltonian quantization, we give a prescription for constructing semiclassical matter-geometry states for homogeneous and isotropic cosmological models. These "collective" states arise as infinite linear combinations of fundamental excitations in an unconventional "polymer" quantization. They satisfy a number of properties characteristic of semiclassicality, such as peaking on classical phase space configurations. We describe how these states can be used to determine quantum corrections to the classical evolution equations, and to compute the initial state of the universe by a backward time evolution.Comment: 13 page

    Growth Hormone, Insulin, And Replacement Or Storage Of Nitrogen

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