Analysis of quality of life among asthmatic individuals with obesity and its relationship with pulmonary function: cross-sectional study

FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOThe combined effect of obesity and asthma may lead to significant impairment of quality of life (QOL). The aim here was to evaluate the prevalence of asthma among obese individuals, characterize the severity of impairment of quality of life and measure it1354332338FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOsem informaçã

Respiratory evaluation through volumetric capnography among grade III obese and eutrophic individuals: a comparative study

Excess trunk body fat in obese individuals influences respiratory physiological function. The aims of this study were to compare volumetric capnography findings (VCap) between severely obese patients and normal-weight subjects and to assess whether there is any association between neck circumference (NC), waist-hip ratio (WHR) and VCap among grade III obese individuals. DESIGN AND SETTING:Analytical observational case-matched cross-sectional study, University of Campinas. METHODS: This cross-sectional study compared VCap variables between 60 stage III obese patients and 60 normal-weight individuals. RESULTS: In comparison with the normal-weight group, obese patients presented higher alveolar minute volume (8.92 +/- 4.94 versus 6.09 +/- 2.2; P = < 0.0001), CO2 production (278 +/- 91.0 versus 209 +/- 60.23; P < 0.0001), expiratory tidal volume (807 +/- 365 versus 624 +/- 202; P = 0.005), CO2 production per breath (21.1 +/- 9.7 versus 16.7 +/- 6.16; P = 0.010) and peak expiratory flow (30.9 +/- 11.9 versus 25.5 +/- 9.13; P = 0.004). The end-expiratory CO2 (PetCO(2)) concentration (33.5 +/- 4.88 versus 35.9 +/- 3.79; P = 0.013) and the phase 3 slope were normalized according to expired tidal volume (0.02 +/- 0.05 versus 0.03 +/- 0.01; P = 0.049) were lower in the obese group. CONCLUSIONS: The greater the NC was, the larger were the alveolar minute volume, anatomical dead space, CO2 production per minute and per breath and expiratory volume; whereas the smaller were the phase 2 slope (P2SIp), phase 3 slope (P3SIp) and pressure drop in the mouth during inspiration1372177183COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES01-P-4354-1

Influência da perda de peso na melhora das variáveis espirométricas e na capnografia volumétrica: um estudo de caso

Obesity causes important changes in lung function, and some tests, such as spirometry and volumetric capnography (VCap), may help diagnose these complications. Objective was to describe the influence of weight loss on improvement of lung function. An individual with morbid obesity grade III, who participated in the multidisciplinary weight loss approach of the HC of Unicamp and was submitted to initial and final evaluations of anthropometric measures and pulmonary function, was evaluated. Spirometry, volumetric capnography and risk of developing sleep apnea were performed by the Berlin questionnaire. After weight loss of 90 kg, BMI of 28 kg / m², improvement in spirometric values was observed in the first and second moments in the variables of forced vital capacity (FVC), final expiratory volume in the first second (FEV1), final expiratory flow. In volumetric capnography, there was an increase in alveolar minute volume [MValv (L)], minute volume of airway space [MVd aw (L)], peak expiratory flow and [PEF (L / min)]. risk for the development of obstructive sleep apnea has evolved from high to low risk. Conclusion: The multidisciplinary approach to weight loss is an important tool to assist the individual in the process of losing weight in an educational and healthy way. Weight loss occurs as a result of effort and learning and leads to health benefits such as improved lung function and mechanics and quality of sleep.A obesidade provoca alterações importantes na função pulmonar, e alguns exames, como espirometria e capnografia volumétrica (VCap), podem ajudar a diagnosticar essas complicações. Objetivo foi descrever a influência da perda de peso na melhora da função pulmonar. Foi avaliado um indivíduo com obesidade mórbida grau III, que participou da abordagem de perda de peso multidisciplinar do HC da Unicamp e foi submetido a avaliações iniciais e finais de medidas antropométricas e da função pulmonar. Foi realizada espirometria, capnografia volumétrica e risco de desenvolvimento da Apneia do Sono pelo questionário de Berlim.  Após a perda de peso de 90kg, IMC de 28kg / m², observou-se melhora nos valores espirométricos no primeiro e segundo momentos nas variáveis de capacidade vital forçada (CVF), volume expiratório final no primeiro segundo (FEV1), fluxo expiratório final. Já na capnografia  volumétrica  houve aumento do volume minuto alveolar [MValv (L)],  volume minuto do espaço morto das vias aéreas [MVd aw (L)], pico de fluxo expiratório e  [PFE (L / min)], A classificação de risco para o desenvolvimento da apneia obstrutiva do sono evoluiu de alto a baixo risco. Conclusão: A abordagem multidisciplinar da perda de peso é uma ferramenta importante para auxiliar o indivíduo no processo de emagrecimento de forma educativa e saudável. A perda de peso ocorre como resultado do esforço e da aprendizagem e leva a benefícios para a saúde, como melhora da função e mecânica pulmonar e qualidade do sono