The XRF080109-SN2008D and a decade of GRB-Jet-SN connection

Last and nearest GRB-XRF 080109 has been an exceptional lesson on GRB nature. After a decade (since 25 April 08) we know that Supernovae may often contain a Jet. Its persistent activity may shine on axis as a GRBs. Such a persistent, thin beamed gamma jet may be powered by either a BH (Black Holes) or Pulsars. Late stages of these jets may loose the SN traces and appear as a short GRB or a long orphan GRB (depending on jet angular velocity and view angle). XRF are peripherical viewing of the jets. These precessing and spinning gamma jet are originated by Inverse Compton and-or Synchrotron Radiation at pulsars or micro-quasars sources, by ultra-relativistic electrons. These Jets are most powerful at Supernova birth, blazing, once on axis, to us and flashing GRB detector. The trembling of the thin jet explains naturally the observed erratic multi-explosive structure of different GRBs. The jets are precessing (by binary companion or inner disk asymmetry) and decaying by power on time scales of few hours, but they keep staying inside the observer cone view only a few seconds duration times (GRB); the jet is thinner in gamma and wider in X band. This explain the wider and longer X GRB afterglow duration and the rare presence of X-ray precursors.Comment: 11 pages, 12 figure

Vacuum solutions with nontrivial boundaries for the Einstein-Gauss-Bonnet theory

The classification of certain class of static solutions for the Einstein-Gauss-Bonnet theory in vacuum is presented. The spacelike section of the class of metrics under consideration is a warped product of the real line with a nontrivial base manifold. For arbitrary values of the Gauss-Bonnet coupling, the base manifold must be Einstein with an additional scalar restriction. The geometry of the boundary can be relaxed only when the Gauss-Bonnet coupling is related with the cosmological and Newton constants, so that the theory admits a unique maximally symmetric solution. This additional freedom in the boundary metric allows the existence of three main branches of geometries in the bulk, containing new black holes and wormholes in vacuum.Comment: Prepared for the proceedings of the 7th Alexander Friedmann International Seminar on Gravitation and Cosmology, July 2008, Joao Pessoa, Brasil. 4 pages, References adde

Symposium: Gender, Health, and the Constitution: Reforming Clinical Trial Pregnancy Exclusions

This essay argues the exclusion of pregnant people from drug and biologic clinical trials is paternalistic, unjust, and counterproductive because the failure to include pregnant people in experimental trials can enhance risks to maternal and fetal health. Bioethicists, legal scholars, and other researchers have pleaded for reform in this context for decades. This article describes pregnancy medical drug use and the genesis and evolution of federal regulations and policies that operate to exclude pregnant people from clinical trials. It argues that the implementation of legal reforms that ensure the inclusion of pregnant people in clinical trials is imperative given Covid, the likelihood of enhanced pregnancy drug use surveillance and policing post-Dobbs, and the potential implications of the challenge to the FDA’s approval of mifepristone. It proposes three categories of reforms: regulatory reforms to the current clinical trials participation rules that pertain to pregnant people, statutory mandates and incentives aimed at enhancing the inclusion of pregnant people in clinical trials, and legal reforms to mitigate research liability concerns