11 research outputs found

    Особенности представления малой родины в материалах духовной периодики Курской губернии конца XIX — начала XX века

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    Creative works of amateur authors are significant in the reflection of ethnic culture in the provincial periodicals. In the publications of “Kurskie eparhialinie vedomosti” (“Kursk diocesan Gazette”) the fact of existence and dynamic development of the clergy subculture in the Kursk province was fixed. The study of peculiarities concerning the concept of “a Small Motherland” in the poetic experience of provincial authors will allow to reconstruct the important parts of the cultural space in pre-1917 Russian province and also to promote the deep understanding of provinces’ role in literary process at the end of the XIX — the beginning of the XX century.Творчество непрофессиональных авторов занимает существенное место как отражение культуры этноса в провинциальной периодике. «Курские епархиальные ведомости» в своих публикациях зафиксировали факт существования и динамичного развития субкультуры духовенства Курской губернии. Изучение особенностей концепта «малой родины» в поэтических опытах местных авторов позволит реконструировать значимые области культурного пространства Российской провинции дооктябрьской поры, а также способствовать глубокому пониманию роли провинции в литературном процессе XIX — начала XX века

    Love as a Fictitious Commodity: Gift-for-Sex Barters as Contractual Carriers of Intimacy

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    Abstract Gift-for-sex (GFS) barters are a niche practice potentially representing the commodification of everyday dating practices. We inquire how GFS exchanges are practiced and understood in contemporary Russia. Second, we situate these in relation to contemporary economic culture. Our project provides answers in two steps based on online content. First, we identify GFS exchange practices within a major dating website. Next, we take the signals exchanged in those dating profiles and display their intersubjective meanings in Russia based on blogs and discussion fora. Our analysis focuses on gender roles and inter-gender conflicts, the use of economic jargon, the link between luxury consumption and sexuality, and understandings of gift-giving and generosity, in order to show how GFS barters, despite being contractual, carry emotional and romantic content. As such, love is under a constant conversion process, through the medium of the contractual gift, into the fictitious commodity form

    Bifunctional Magnetite–Gold Nanoparticles for Magneto-Mechanical Actuation and Cancer Cell Destruction

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    Magnetite–gold dumbbell nanoparticles are essential for biomedical applications due to the presence of two surfaces with different chemical natures and the potential combination of magnetic and plasmonic properties. Here, the remote actuation of Fe3O4-Au hybrid particles in a rotating (1 Hz, 7 mT), static (7 mT) or pulsed low-frequency (31 Hz, 175 mT, 30 s pulse/30 s pause) magnetic field was studied. The particles were synthesized by a high-temperature wet chemistry protocol and exhibited superparamagnetic properties with the saturation magnetization of 67.9 ± 3.0 Am2 kg−1. We showcased the nanoparticles’ controlled aggregation in chains (rotating/static magnetic field) in an aqueous solution and their disaggregation when the field was removed. The investigation of nanoparticle uptake by LNCaP and PC-3 cancer cells demonstrated that Fe3O4-Au hybrids mainly escaped endosomes and accumulated in the cytoplasm. A significant fraction of them still responded to a rotating magnetic field, forming short chains. The particles were not toxic to cells at concentrations up to 210 μg (Fe3O4) mL−1. However, cell viability decrease after incubation with the nanoparticles (≥70 μg mL−1) and exposure to a pulsed low-frequency magnetic field was found. We ascribe this effect to mechanically induced cell destruction. Overall, this makes Fe3O4-Au nanostructures promising candidates for intracellular actuation for future magneto-mechanical cancer therapies

    Bifunctional Magnetite–Gold Nanoparticles for Magneto-Mechanical Actuation and Cancer Cell Destruction

    No full text
    Magnetite–gold dumbbell nanoparticles are essential for biomedical applications due to the presence of two surfaces with different chemical natures and the potential combination of magnetic and plasmonic properties. Here, the remote actuation of Fe3O4-Au hybrid particles in a rotating (1 Hz, 7 mT), static (7 mT) or pulsed low-frequency (31 Hz, 175 mT, 30 s pulse/30 s pause) magnetic field was studied. The particles were synthesized by a high-temperature wet chemistry protocol and exhibited superparamagnetic properties with the saturation magnetization of 67.9 ± 3.0 Am2 kg−1. We showcased the nanoparticles’ controlled aggregation in chains (rotating/static magnetic field) in an aqueous solution and their disaggregation when the field was removed. The investigation of nanoparticle uptake by LNCaP and PC-3 cancer cells demonstrated that Fe3O4-Au hybrids mainly escaped endosomes and accumulated in the cytoplasm. A significant fraction of them still responded to a rotating magnetic field, forming short chains. The particles were not toxic to cells at concentrations up to 210 μg (Fe3O4) mL−1. However, cell viability decrease after incubation with the nanoparticles (≥70 μg mL−1) and exposure to a pulsed low-frequency magnetic field was found. We ascribe this effect to mechanically induced cell destruction. Overall, this makes Fe3O4-Au nanostructures promising candidates for intracellular actuation for future magneto-mechanical cancer therapies
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