5,497 research outputs found
Towards modeling of comprehensive assessment for licensing in higher education
In the modern society information technologies, services, quality become the determinative factors of success of any business. The questions of quality management are especially relevant in social sphere, since organization oriented on quality of its processes provides the improvement of people living standards. Information computer technologies (ICT) are the powerful tool for increasing the performance of decision-making processes. Formalization of management problems and adequate mathematical models provide ICT with techniques and methods of solving the application problems in different domains and improving business performance. Higher education is a unique social and economic environment. The quality of its functioning influences many processes of successive development of society.Therefore elaboration of ICT in higher education domain remains the challenging problem for specialists in computer sciences
Designing of a Community-based Translation Center
Interfaces that support multi-lingual content can reach a broader community.
We wish to extend the reach of CITIDEL, a digital library for computing
education materials, to support multiple languages. By doing so, we hope that
it will increase the number of users, and in turn the number of resources. This
paper discusses three approaches to translation (automated translation,
developer-based, and community-based), and a brief evaluation of these
approaches. It proposes a design for an online community translation center
where volunteers help translate interface components and educational materials
available in CITIDEL.Comment: 8 pages, 4 figure
Hexakis(dimethylformamide)bis(hexaphenylcyclohexasiloxanehexaolato)hexacopper(II) Dimethylformamide Solvate
The sandwich-like title complex, hexakis(dimethylformamide)-1O,2O,3O,4O,5O,6O-bis[2,4,6,8,10,12-hexaphenylsiloxane-2,4,6,8,10,12-hexaolato(6-)-1:22O1,2:32O2,3:42O3,- 4:52O4,5:62O5,1:62O6]hexacopper(II) tetrakis(dimethylformamide) solvate, [Cu6(C3H7NO)6{(C6H5)6O12Si6}2].4C3H7NO, is comprised of two regular crown-shaped macrocyclic hexadentate organosiloxanolate ligands chelating a flat Cu6 hexagon, as in the ethanol-solvated analogue investigated previously. The title complex has a more distorted shape than the trigonal ethanol-solvated analogue, being slightly side-oblated, but still contains a large empty inner channel accessible by small molecules (the diameter of the free cross-section being about 2.5 Å). Each CuII ion has square-pyramidal coordination with four basal siloxanolate O atoms and an apical dimethylformamide (DMFA) molecule (coordinated through its carbonyl group). The average bond lengths are: Cu-O(Si) 1.964 (11) Å and Cu-O(DMFA) 2.215 (10) Å. The structure contains four additional DMFA molecules per complex unit, linked by weak C-HO hydrogen bonds. Unexpectedly, the C=O bond length is longer [1.248 (10) and 1.255 (9) Å] in the uncoordinated DMFA molecules than in the coordinated [1.214-1.227 (7) Å]
Filter Retardation Assay for Detecting and Quantifying Polyglutamine Aggregates Using Caenorhabditis elegans Lysates
Protein aggregation is a hallmark of several neurodegenerative diseases and is associated with impaired protein homeostasis. This imbalance is caused by the loss of the protein's native conformation, which ultimately results in its aggregation or abnormal localization within the cell. Using a C. elegans model of polyglutamine diseases, we describe in detail the filter retardation assay, a method that captures protein aggregates in a cellulose acetate membrane and allows its detection and quantification by immunoblotting
Nuclear/Cytoplasmic Fractionation of Proteins from Caenorhabditis elegans
C. elegans is widely used to investigate biological processes related to health and disease. To study protein localization, fluorescently-tagged proteins can be used in vivo or immunohistochemistry can be performed in whole worms. Here, we describe a technique to localize a protein of interest at a subcellular level in C. elegans lysates, which can give insight into the location, function and/or toxicity of proteinsNational Institutes of Health National Centre for Research Resources (NIH)European Research Council (ERC)USANIH National Center for Research Resources (NCRR)Japan National BioResource Projec
Quantum Size Effects and Transport Phenomena in PbSe Quantum Wells and PbSe/EuS Superlattices
It is established that the room-temperature dependences of transport properties on the total thickness of PbSe layers d in PbSe/EuS superlattices exhibit an oscillatory behavior. It is shown that the oscillation period Δd practically coincides with the period of the thickness oscillations observed earlier in single PbSe/EuS quantum well. The non-monotonic character of these dependences is attributed to quantum size effects. The theoretically estimated and experimentally determined Δd values are in good agreement
Solitons supported by singular spatial modulation of the Kerr nonlinearity
We introduce a setting based on the one-dimensional (1D) nonlinear
Schroedinger equation (NLSE) with the self-focusing (SF) cubic term modulated
by a singular function of the coordinate, |x|^{-a}. It may be additionally
combined with the uniform self-defocusing (SDF) nonlinear background, and with
a similar singular repulsive linear potential. The setting, which can be
implemented in optics and BEC, aims to extend the general analysis of the
existence and stability of solitons in NLSEs. Results for fundamental solitons
are obtained analytically and verified numerically. The solitons feature a
quasi-cuspon shape, with the second derivative diverging at the center, and are
stable in the entire existence range, which is 0 < a < 1. Dipole (odd) solitons
are found too. They are unstable in the infinite domain, but stable in the
semi-infinite one. In the presence of the SDF background, there are two
subfamilies of fundamental solitons, one stable and one unstable, which exist
together above a threshold value of the norm (total power of the soliton). The
system which additionally includes the singular repulsive linear potential
emulates solitons in a uniform space of the fractional dimension, 0 < D < 1. A
two-dimensional extension of the system, based on the quadratic nonlinearity,
is formulated too.Comment: Physical Review A, in pres
- …