Expression of P63 in Oral Mucosa Covering Impacted Teeth: An Immunohistochemical Study

Objective: The purpose of the study was to examine the expression of p63 gene in asymptomatic enclosed lower third molar covering oral mucosa.  Design:  :  50 samples of normal oral mucosa taken from 50 patients  who underwent third molar surgery were included into the study. The samples were subdivided into two groups. One group was made of oral mucosa covering completely impacted teeth, while other group was made of oral mucosa  covering partially impacted teeth.Only nuclear staining of the cells was evaluated by percentage of positive cells.Results: : Immunoexpression of p63 was almost equal in submucosa cells of both groups, showing a faint to intermediate positivity. Basal layer of oral mucosa covering completely  enclosed teeth have shown a stronger expression of p63 than it was the case with the other group. Conclusion: Expression of p63 is noticed in basal and suprabasal layers of oral mucosa covering impacted teeth. Weak expression of p63 in basal layer of oral mucosa covering partially impacted teeth, migh be associated with teeth eruption, lesser number of stem cells and thinner  mucosa patch than it is a case with oral mucosa covering completely impacted teeth.   &nbsp

Prosthetic rehabilitation with dental implants after treatment of a keratocystic odontogenic tumor: case report

Keratocystic odontogenic tumor (KCOT), formerly known as the odontogenic keratocyst (OKC) is a benign intraosseous lesion, characterized by invasive growth and high rate of recurrences. Although it is not frequently seen, KCOT may be associated with unerupted teeth and without relevant histopathological examinations, might be mistaken with dentigerous cyst. A 26 year-old male patient referred to our department with complaints of two months persisting painless swelling on the left side of mandible. Clinical and radiographic examinations revealed an impaction of the horizontally positioned left lower second premolar surrounded by a well-circumscribed radiolucent mass, located between the left canine and the second molar, suspected to be a cyst. The aim of this report is to present a therapeutical approach to keratocystic odontogenic tumor associated with impacted tooth and prosthetic rehabilitation with dental implants after an initial treatment. The patient is under follow up for 31 months since implant placement was done, without any complaints or complication

Does Root Canal Overfilling Cause Development Of Radicular Cyst? Report of Two Cases

Overfilling of root canal is an endodontic complication, characterized by extrussion of filling materials into the periapical tissues, which might be a causative agent of important pathological changes. This report presents two cases of overfilled left upper and lower molar teeth associated with potential development of large radicular cysts. In the first case a cyst of mandible, causing sensory disturbances, was diagnosed five years after endodontic treatment, while the second case describes a cyst in maxillary antrum, diagnosed two years after an endodontic therapy was performed.In the present cases, the patients underwent a cysts enucleation with extraction of endodontically treated teeth. This report also discuss about influence of overfilling as a potential etiological factor on radicular cyst development