Synthesis and Study of Spectral-luminescent and Biologically Active Properties of Mixed-ligand Complexes of Cobalt(II) and Copper(II) with Rutin and Glycine

Mixed-ligand complexes of Co(II) and Cu(II) with rutin and glycine were synthesized and studied by the method of "block" synthesis. The composition and structure of the synthesized compounds in solutions and in the solid state were studied, and their spectral and luminescent properties were determined. It is shown that the mixed-ligand complexes have the composition MII(Gly)2(Rut), while the coordination of 3-d metal ions occurs through the catechol fragment of rutin and the carboxyl and amino groups of two glycine molecules. For complexes in solutions, luminescence was detected in the visible region of the spectrum (~500–540 nm). It is shown that 3-d metal ions quench the luminescence of rutin, but in the presence of glycinate ion, the luminescence intensity of the complexes increases. The antibacterial activity of the complexes against pathological bacteria Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, P. Aeruginosa was studied. It has been shown that the synthesized compounds have an antimicrobial effect

Priming winter wheat seeds with the bacterial quorum sensing signal N-hexanoyl-L-homoserine lactone (C6-HSL) shows potential to improve plant growth and seed yield

Several model plants are known to respond to bacterial quorum sensing molecules with altered root growth and gene expression patterns and induced resistance to plant pathogens. These compounds may represent novel elicitors that could be applied as seed primers to enhance cereal crop resistance to pathogens and abiotic stress and to improve yields. We investigated whether the acyl-homoserine lactone N-hexanoyl-L-homoserine lactone (C6-HSL) impacted winter wheat (Triticum aestivum L.) seed germination, plant development and productivity, using two Ukrainian varieties, Volodarka and Yatran 60, in both in vitro experiments and field trials. In vitro germination experiments indicated that C6-HSL seed priming had a small but significant positive impact on germination levels (1.2x increase, p < 0.0001), coleoptile and radicle development (1.4x increase, p < 0.0001). Field trials over two growing seasons (2015-16 and 2016-17) also demonstrated significant improvements in biomass at the tillering stage (1.4x increase, p < 0.0001), and crop structure and productivity at maturity including grain yield (1.4 – 1.5x increase, p < 0.0007) and quality (1.3x increase in good grain, p < 0.0001). In some cases variety effects were observed (p ≤ 0.05) suggesting that the effect of C6-HSL seed priming might depend on plant genetics, and some benefits of priming were also evident in F1 plants grown from seeds collected the previous season (p ≤ 0.05). These field-scale findings suggest that bacterial acyl-homoserine lactones such as C6-HSL could be used to improve cereal crop growth and yield and reduce reliance on fungicides and fertilisers to combat pathogens and stress