156 research outputs found
Biospecific Affinity Chromatography: Computational Modelling via Lattice Boltzmann Method and Influence of Lattice-Based Dimensionless Parameters
Based on a dynamic (i.e. time-dependent) one-dimensional approach, this work applied lattice Boltzmann method (LBM) to computationally model biospecific affinity chromatography (BAC). With governing equations expressed in lattice-based dimensionless form, LBM was implemented in D1Q2 lattice by assigning particle distribution functions to adsorbate concentration in both fluid and solid phases. The LBM simulator was firstly tested in view of a classic BAC work on lysozyme and the streaming step relating to adsorbate concentration in the solid-phase was suppressed from the LBM code with no loss of functionality. Expected behaviour of breakthrough curves was numerically reproduced and the influence of lattice-based dimensionless parameters was examined. The LBM simulator was next applied so as to assess lattice-based dimensionless parameters regarding an experimental BAC work on lipase
Laparoscopic findings in patients with nonalcoholic steatohepatitis
ArticleLIVER INTERNATIONAL. 26(1): 32-38 (2006)journal articl
Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population
The definitive version is available at www.blackwell-synergy.com.ArticleLIVER INTERNATIONAL. 26(8): 956-963 (2006)journal articl
Effect of Pulsed or Continuous Delivery of Salt on Sensory Perception Over Short Time Intervals
Salt in the human diet is a major risk factor for hypertension and many countries have set targets to reduce
salt consumption. Technological solutions are being sought
to lower the salt content of processed foods without altering their taste. In this study, the approach was to deliver salt solutions in pulses of different concentrations to determine whether a pulsed delivery profile affected sensory perception of salt. Nine different salt profiles were delivered by a Dynataste device and a trained panel assessed their saltiness using timeâintensity and single-score sensory techniques. The profile duration (15 s) was designed to match eating conditions and the effects of intensity and duration of the pulses on sensory perception were investigated. Sensory results from the profiles delivered in either water or in a bouillon base were not statistically different. Maximum perceived salt intensities and the area under the timeâ
intensity curves correlated well with the overall perceived
saltiness intensity despite the stimulus being delivered as
several pulses. The overall saltiness scores for profiles
delivering the same overall amount of sodium were statistically not different from one another suggesting that, in this system, pulsed delivery did not enhance salt
perception but the overall amount of salt delivered in each
profile did affect sensory perception
A Case of Refractory Subcutaneous Panniculitis-like T-cell Lymphoma with Bone Marrow and Lung Involvement Treated Successfully with Oral Etoposide
Short communicatio
Histology of the Pharyngeal Constrictor Muscle in 22q11.2 Deletion Syndrome and Non-Syndromic Children with Velopharyngeal Insufficiency
Plastic surgeons aim to correct velopharyngeal insufficiency manifest by hypernasal speech with a velopharyngoplasty. The functional outcome has been reported to be worse in patients with 22q11.2 deletion syndrome than in patients without the syndrome. A possible explanation is the hypotonia that is often present as part of the syndrome. To confirm a myogenic component of the etiology of velopharyngeal insufficiency in children with 22q11.2 deletion syndrome, specimens of the pharyngeal constrictor muscle were taken from children with and without the syndrome. Histologic properties were compared between the groups. Specimens from the two groups did not differ regarding the presence of increased perimysial or endomysial space, fiber grouping by size or type, internalized nuclei, the percentage type I fibers, or the diameters of type I and type II fibers. In conclusion, a myogenic component of the etiology of velopharyngeal insufficiency in children with 22q11.2 deletion syndrome could not be confirmed
Colorimetric determination of alpha and beta-cyclodextrins and studies on optimization of CGTase production from B. firmus using factorial designs
Theoretical characterization of excitation energy transfer in chlorosome light-harvesting antennae from green sulfur bacteria
Efficient Molecular Dynamics Simulations of Multiple Radical Center Systems Based on the Fragment Molecular Orbital Method
Daily rhythm of NaCl intake in rats fed low-Ca2+ diet: relation to plasma and urinary minerals and hormones
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