Entrepreneurial Orientation, Business Development Services, Business Environment, and Performance: A Critical Literature Review

The role of entrepreneurial orientation in firms has been a major area of interest to many scholars in the past. Entrepreneurially oriented firms are innovative, calculated risk-takers, and proactively reach markets ahead of their competitors. This paper examines the role of business development services, internal and external business environments on the relationship between entrepreneurial orientation and firm’s performance. The article is a theoretical discourse and uses literature from secondary sources in the analysis. The paper finds that past studies conceptualized entrepreneurial orientation as a three factor single-dimensional model and a five factor multidimensional model. Studies using the three factor model have reported different results to those adopting the five factor approach. This has led to inconsistencies in the empirical results of entrepreneurial orientation on firm’s performance. This article also finds that business development services play a mediating role in the entrepreneurial orientation and performance relationship, and that external environment moderates this relationship. However, the paper finds no role of internal environment in the EO-firm’s performance relationship. The paper concludes that the link between entrepreneurial orientation and performance is still a worthy area for further study since contradictions still exist in empirical studies. This study recommends that future studies can use a contingency framework to focus on how other factors are likely to affect this relationship

The Effect of Business Development Services on Performance of Small and Medium Manufacturing Enterprises in Kenya

Small and Medium Enterprises have been regarded to play significant roles of job creation, poverty alleviation and economic development of many countries worldwide. These enterprises are however affected by many different factors. How these factors manifest singly or jointly is therefore a key concern for these organizations. Vital among these factors are business development services that affect how organizations produce and sell their goods and services. There is however a dearth of studies focusing on effects of aspects of business development services on organizational performance in Kenya. This study aimed at establishing how market access, procurement services and infrastructure facilities affect performance of small and medium manufacturing enterprises in Kenya. The study adopted a cross sectional survey design and examined primary data collected from 150 enterprises in Nairobi. Inferential statistics were used to interrogate relationships between independent variables and performance while descriptive statistics were used to determine distribution, central tendency and dispersion and hence establish conformity to linear regression requirements. Contrary to expectation, the results for market access did not show any relationship but procurement services and infrastructure facilities each had a positive and significant influence on performance of the enterprises. Furthermore, it was established that the joint effect of the three variables on performance of studied firms is greater than their individual effect. This study therefore concludes that, since procurement services and infrastructure facilities showed a positive influence on performance of small and medium manufacturing enterprises in Kenya, these enterprises should adopt strategies that enhance procurement and improve infrastructure facilities to experience better performance

The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

INTRODUCTION Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic. RATIONALE We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs). RESULTS Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants. CONCLUSION Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century

Controlling desolvation through polymer-assisted grinding

We demonstrate the ability to controllably desolvate a crystal-solvate system in a step-wise fashion through polymer-assisted grinding by varying the type and proportion of polymer agent used. A plausible mechanistic explanation is proposed based on a combination of experimental evidence and computational analysis. Specifically, Raman spectroscopy, total scattering pair distribution function analysis and computed reaction energies suggest that the desolvation process is associated with preferred interactions between the solvent molecules and specific polymers. This approach could potentially be extended to any type of material, including heat-sensitive materials, where classical desolvation by thermal processes is not possible, and provides an additional route for formulation processing

Controlling desolvation through polymer-assisted grinding

We demonstrate the ability to controllably desolvate a crystal-solvate system in a step-wise fashion through polymer-assisted grinding by varying the type and proportion of polymer agent used. A plausible mechanistic explanation is proposed based on a combination of experimental evidence and computational analysis. Specifically, Raman spectroscopy, total scattering pair distribution function analysis and computed reaction energies suggest that the desolvation process is associated with preferred interactions between the solvent molecules and specific polymers. This approach could potentially be extended to any type of material, including heat-sensitive materials, where classical desolvation by thermal processes is not possible, and provides an additional route for formulation processing

A Review of the Health Act, 2017 from an Access, Quality and Cost Paradigm

The Health Act 2017 was recently enacted to establish a unified health system, to coordinate the interrelationship between the national government and the county government health systems, to provide for regulation of health care service, and health care service providers, health products and health technologies and for connected purposes. The enactment of this Act comes against the backdrop of a health care system that is riddled with structural barriers inhibiting access to health care services with resultant grave consequences. The enactment of the Act is therefore, timely given the constitutional context of the right to the highest attainable standards of health care. However, the key question remains whether the Act sufficiently addresses some of the concerns prevalent in the Kenyan health care system. This paper examines the Act using the lens of access, cost, and quality which are the chief concerns of any health care system. The paper examines the salient issues in the Act under these three broad limbs while examining whether the Act contain provisions that improve access to, reduce costs and improves quality of health care provided in Kenya. The analysis adopted in this paper flows from the understanding of health care as a right with concomitant obligations on the State and its agencies and also within the context of devolved governance adopted by the Constitution in 2010 while also appreciating international best practices and norms