Ocean climate data for user community in West and Central Africa: Needs, opportunities, and challenges

The urgent need to improve data delivery systems needed by scientists studying ocean role in climate and climate characteristics has been manifested in recent years because of the unprecedented climatic events experienced in many parts of the world. Indeed, there has been a striking and growing realization by governments and the general public indicating that national economies and human welfare depend on climate and its variability. In West and Central Africa, for instance climatic events, which have resulted in floods and droughts, have caused a lot of concern to both governments and people of the region. In particular, the droughts have been so widespread that greater awareness and concern have become generated for the need to find solutions to the problems created by the consequences of the climatic events. Particularly in the southern border regions of the Sahara Desert as well as in the Sahel region, the drought episodes considerably reduced food production and led to series of socioeconomic problems, not only in the areas affected by the droughts, but also in the other parts of West Africa. The various climatic variabilities which have caused the climatic events are no doubt related to the ocean-atmosphere interactions. Unfortunately, not much has been done on the understanding of these interactions, particularly as they affect developing countries. Indeed, not much has been done to develop programs which will reflect the general concerns and needs for researching into the ocean-atmosphere systems and their implications on man-environmental systems in many developing countries. This is for example, true of West and Central Africa, where compared with the middle latitude countries, much less is known about the characteristics of the ocean-atmosphere systems and their significance on man-environmental systems of the area

An overview of sustainable practices in food processing supply chain environments

Climate change has been a great challenge that the world is facing, it is a menace to the society and it is causing more damage than expected. The researchers are working tirelessly to reduce its impact on the planet in order to save the future. Mitigation of greenhouse gas emission and other sustainable practices is encouraged every day to make the world a better place to live Sustainable practice has been identified as one of the major tools to control this greenhouse gas emission especially in the emergent nations where industrialization is now growing rapidly. This paper discusses and analyzes the food security and food processing industry in the emergent nations. It also reviews literature on food processing, supply chain environments, sustainability and sustainable practices in relation to how these could help in promoting the sustainable development and environmental protection goals in the emergent nations

Low density lipoprotein oxidation by ferritin at lysosomal pH

Oxidation of low density lipoprotein (LDL) has been proposed to be involved in the pathogenesis of atherosclerosis. We have previously shown that LDL can be oxidised by iron in lysosomes. As the iron-storage protein ferritin might enter lysosomes by autophagy, we have investigated the ability of ferritin to catalyse LDL oxidation at lysosomal pH. LDL was incubated with ferritin at 37 °C and pH 4.5 and its oxidation monitored spectrophotometrically at 234 nm by the formation of conjugated dienes and by measuring oxidised lipids by HPLC or a tri-iodide assay. Iron released from ferritin was measured using the ferrous iron chelator bathophenanthroline and by ultrafiltration followed by atomic absorption spectroscopy. LDL was oxidised effectively by ferritin (0.05–0.2 μM). The oxidation at lysosomal pH (pH 4.5) was much faster than at pH 7.4. Ferritin increased cholesteryl linoleate hydroperoxide, total lipid hydroperoxides and 7-ketocholesterol. Iron was released from ferritin at acidic pH. The iron chelators, diethylenetriaminepentaacetate and EDTA, and antioxidant N,N ׳-diphenyl-p-phenylenediamine inhibited the oxidation considerably, but not entirely. The antioxidant tempol did not inhibit the initial oxidation of LDL, but inhibited its later oxidation. Cysteamine, a lysosomotropic antioxidant, inhibited the initial oxidation of LDL in a concentration-dependent manner, however, the lower concentrations exhibited a pro-oxidant effect at later times, which was diminished and then abolished as the concentration increased. These results suggest that ferritin might play a role in lysosomal LDL oxidation and that antioxidants that accumulate in lysosomes might be a novel therapy for atherosclerosis. 1. Introduction The oxidation of low density lipoprotein (LDL) has been proposed to occur in the extracellular space of the arterial wall and lead to the formation of foam cells and atherosclerosis (Steinberg, 2009). The oxidation of LDL by cells requires the presence of micromolar concentrations of the transition metals copper or iron in the medium (Steinbrecher et al., 1984; Leake and Rankin, 1990). Free copper or iron are not readily available in the plasma or interstitial fluid because they exist in a tightly bound form. A number of mechanisms have been proposed to be involved in the oxidation of LDL in vivo, but at present, there is no consensus on the predominant mechanism by which LDL is modified in vivo. Cultured macrophages have been shown, however, to take up aggregated or acetylated LDL quickly and oxidise it in lysosomes (Wen and Leake, 2007). Cholesterol crystals derived from oxidised LDL in lysosomes have been reported to rupture these organelles in macrophages and activate the NLRP3 inflammasome (Duewell et al., 2010). This might be important as atherosclerosis is a chronic inflammatory disease an

Microanatomical effects of ethanolic extract of Cola nitida on the stomach mucosa of adult wistar rats

The study investigated the microanatomical effects of the extracts of Cola nitida on the stomach mucosa of adult male Wistar rats. Twenty adult male wistar rats were randomly divided into four equal groups of A, B, C and D (n=5). Animals in experimental groups B, C and D were given 600mg/kg body weight of crude extract of Cola nitida each by oral intubation for five, seven and nine consecutive days respectively, while group A (control) received equivalent volume of distilled water. Twenty four hrs after the last administration, the animals were sacrificed; tissues were harvested and fixed in 10% formol saline for histological analysis. The study revealed necrotized surface epithelium, degenerated gastric mucosa, and loss of glandular elements in the stomachs of experimental groups’ vis-à-vis the control group. These observations were days-dependent; as those groups which received the extract for higher number of days were seen to be adversely affected. In conclusion, Cola nitida at 600mg/kg body weight can cause gastric lesion in animals. This lesion may be pronounced if the administration continued for days. Cola nitida should, therefore, be taken with caution to avoid gastric complications.Keyword: Cola nitida, necrotized, degenerated, stomach mucosa, microanatomy, glandular element

Shoulder Pain Syndrome Among Nigerians

Objectives: To identify aetiological causes of shoulder pain syndrome among patients attending a rheumatology clinic, and to highlight the therapeutic options.Design: Retrospective study.Setting: A private rheumatology clinic in Lagos, Nigeria from January 2002 to December 2006.Subjects: Forty female adult patients and 26 male adult patients aged 24-79 years. Main outcome measures: Patient reported outcome in terms of pain relief and increased mobility.Results: Sixty six subjects were seen during the study period. Females were more commonly affected and were mostly middle aged. Adhesive capsulitis was the most common condition while septic arthritis and avascular necrosis were least diagnosed 22.7% of the subjects could not, however, be categorised.Conclusion: Shoulder pain syndrome is common among Nigerians. Diagnosis and management are mostly based on the clinical presentations, especially considering the lack of sensitivity of plain radiographs and the high cost of more sensitive MRI. The treatment of these conditions are standard

Impact of Credit Demand on the Productivity of Rice Farmers in South West Nigeria

Employing cross-sectional data from 360 rice farmers selected from three states in South West Nigeria, the study analyzes the impact of credit demand on the productivity of rice farmers. An Endogenous Switching Regression Model (ESRM) that accounts for both heterogeneity and sample selection biases were used to estimate the impact of credit demand on rice productivity in South West Nigeria. In addition, a Tobit regression model was employed to measure the level of participation of rice farmers in the credit market. The result of the first stage (probit model) of the ESRM revealed that household assets, access to service, climate variables, regional variables, and transaction cost are statistically significant in influencing farmers’ credit demand decision. The results of the second stage of the ESRM indicate factors such as household assets and access to service were statistically significant in explaining variations in rice productivity among participants and non-participants in the credit market. Furthermore, the results of the Tobit model showed that the farmers’ location income from rice farming experience, interest rate, and distance to the source of credit are statistically significant determinants of the amount of credit received. These findings suggest that facilitating farmers’ access to credit will improve rice productivity. Therefore, it is imperative for government and development partner to work together in order to improve the conditions for suitable agricultural credit access to rice farmers, especially a review of interest rates. A necessary addition should be developed to the assistance already being provided under Nigeria Incentive-Based Risk Sharing System for Agricultural Lending (NIRSAL) in the form of loan guarantees and other risk-sharing incentives, such as a regulatory environment that supports the modern contractual obligations that are characteristic of well-functioning agricultural financing. This would not only contribute to the intensification of rice production in Nigeria to meet its increasing rice demand, but also improve rice farmers’ productivity and their households’ incomes

Impact of Thrift and Loan Associations in Reducing Poverty for Economic Development of Farmers in Lafia Local Government Area of Nasarawa State, Nigeria

In rural areas, low level people hardly ever get access to credit facilities and farm inputs due to their socio economic status, thus the poverty level of people in rural areas continue to worsen. This study was carried out to examine the impact of thrift and loan associations in reducing poverty for economic development of farmers in Lafia Local Government Area of Nasarawa State. A multi-stage sampling technique was used in selecting the respondents. Data were collected through questionnaire and interview schedule. Tools for analyses were descriptive statistics and multiple regressions. Findings revealed that household size, farm income, non-farm income, educational level and interest rate charged on credit were the significant factors that influenced the level of participation of members in thrift and loan associations. The study concludes that Micro-lending through thrift and loans associations has been considered as the solution for poverty reduction. It was therefore recommended that thrift and loan association should be supported to grow their wealth sufficiently through accumulation of enough  institutional  capital  to  finance funded  assets,  provide  cushion  to  absorb  losses, link up farmers with sources of input production thereby reducing poverty among members. Keywords: impact, thrift and loans, association, poverty, economic, developmen

Impact of Thrift and Loan Associations in Reducing Poverty for Economic Development of Farmers in Lafia Local Government Area of Nasarawa State, Nigeria

In rural areas, low level people hardly ever get access to credit facilities and farm inputs due to their socio economic status, thus the poverty level of people in rural areas continue to worsen. This study was carried out to examine the impact of thrift and loan associations in reducing poverty for economic development of farmers in Lafia Local Government Area of Nasarawa State. A multi-stage sampling technique was used in selecting the respondents. Data were collected through questionnaire and interview schedule. Tools for analyses were descriptive statistics and multiple regressions. Findings revealed that household size, farm income, non-farm income, educational level and interest rate charged on credit were the significant factors that influenced the level of participation of members in thrift and loan associations. The study concludes that Micro-lending through thrift and loans associations has been considered as the solution for poverty reduction. It was therefore recommended that thrift and loan association should be supported to grow their wealth sufficiently through accumulation of enough  institutional  capital  to  finance funded  assets,  provide  cushion  to  absorb  losses, link up farmers with sources of input production thereby reducing poverty among members. Keywords: impact, thrift and loans, association, poverty, economic, developmen