Eukaryotic DNA Polymerases: Proposal for a Revised Nomenclature

Pol polymeraseIn 1975, a Greek letter nomenclature system was introduced to designate DNA polymerases from mammalian cells (1). Ten years ago, progress in the biochemical analysis of eukaryotic DNA polymerases and in the isolation of their genes, particularly in the yeast Saccharomyces cerevisiae, necessitated a revision of the Greek letter nomenclature system and an expansion to include all eukaryotic organisms (2). Until a few years ago, this system sufficed to designate the six known DNA polymerases α, β, γ, δ, ε, and ζ

Initial crystallographic study of human PCNA in complex with a peptide containing the noncanonical PIP-box sequence of human DNA polymerase ι

Crystallization and diffraction studies of a human PCNA–Polι peptide complex are reported

Crystallographic study of G178S mutant of human proliferating cell nuclear antigen

Crystallization and diffraction studies of human PCNA G178S mutant are reported