Two kinds of conservatives in Japanese politics and Prime Minister Shinzo Abe's tactics to cope with them

For more about the East-West Center, see http://www.eastwestcenter.org/Akai Ohi, Adjunct Lecturer at the University of Tokyo, Hosei University, and Showa Women's University, explains that "During the period of stable one-party dominance... the LDP managed to bundle support from big corporations and Keidanren... in the face of the socialist threat from rural regions.

ハロルド・ラスキの思想世界 : 20世紀における政治学と公共的知識人

学位の種別: 課程博士審査委員会委員 : （主査）東京大学教授 森 政稔, 東京大学教授 市野川 容孝, 東京大学准教授 山本 芳久, 成城大学教授 木畑 洋一, 法政大学教授 杉田 敦University of Tokyo(東京大学

Kanichi Fukuda and the Spontaneous Growth of "Nationalism" in Postwar East Asia

Kanichi Fukuda (1923-2007) was a professor of politics who taught the history of European political thought at Tokyo University. Although he is known in academia for his study of modern European thinkers, he wrote many essays and articles on contemporary East Asian countries such as China, South Korea, and Japan. The aim of this paper is to focus on his articles regarding political movements in East Asia, and emphasizes the close connection between Fukuda\u27s study of modern Europe and his contemporary commitments to East Asia in the 1960s and 70s. Specifically, this paper examines Fukuda\u27s interpretation of: (1) The Chinese Revolution led by the Communist Party in 1949, (2) The Korean people\u27s protestant against the normalization of diplomatic relations between Japan and South Korea in 1965, and (3) The Japan - U. S. Security Treaty and the Japanese people\u27s opposition to it (known as "the ANPO opposition movement") in 1960. Through these considerations, this paper argues that Fukuda highly valued the spontaneous and democratic rise of "nationalism" in the China and South Korea of his own era, and expected to see similar democratic prospects in the ANPO opposition movement when it took place in 1960.論文Paper

Pseudo-cerebrospinal Fluid Rhinorrhea after Skull Base Surgery : Case Report

Cusimanoらは、pseudo-cerebrospinal fluid(CSF) rhinorrheaという病態を初めて報告したが、我々も同様の一例を経験したので報告した。症例は41歳女性。右三叉神経第1枝領域の知覚鈍麻を主訴とし、petrous先端部に腫瘍性瘤変(tentorial meningioma)を認めた。transpetrosal approachによるpetrosectomyの際、greater superficial petrosal nerve (GSPN)は切断したが、術後2週間後より患側のrhinorrheaを認める様になった。Pseudo-CSF rhinorrheaは, GSPNの切断により自律神経系がアンバランスとなり何らかのhypersensitivityが生じ粘液分泌亢進が起こると考えられた。頭蓋底手術に際し、注意すべき一瘤態と思われた。　A 41-year-old female underwent complete resection of a left petroclival meningioma via an anterior transpetrosal approach, during which the greater superficial petrosal nerve was divided. On the 14th day after the operation, she first noticed leakage of clear fluid from her right nostril whenever the ambient room temperature rose.This pseudo-cerebrospinal fluid rhinorrhea may have developed because of parasympathetic hypersensitivity due to division of the greater superficial petrosal nerve

Efficacy and safety of nanoparticle albumin‐bound paclitaxel monotherapy after immune checkpoint inhibitor administration for advanced non‐small cell lung cancer: A multicenter Phase 2 clinical trial

Abstract Background Whether immunotherapy improves the efficacy or worsens adverse events of subsequent chemotherapy remains unclear. We performed a Phase 2 study to evaluate the efficacy and safety of nanoparticle albumin‐bound paclitaxel (nab‐paclitaxel) as a treatment for advanced non‐small cell lung cancer (NSCLC) after treatment with programmed cell death 1 or programmed death ligand 1 [PD‐(L)1] inhibitor failure. Methods Nab‐paclitaxel (100 mg/m2) was administered on Days 1, 8, and 15 of a 28‐day cycle to patients with advanced NSCLC within 12 weeks after the failure of PD‐(L)1 inhibitor treatment. The primary endpoint was objective response rate (ORR) in all patients; the secondary endpoints were disease control rate (DCR), progression‐free survival (PFS), overall survival (OS), and safety. Results Thirty cases were registered, and 29 cases were included in the analysis. The ORR was 55.2% (95% confidence interval [CI]: 28.1%–79.6%) and the DCR was 86.2% (95% CI: 65.9%–97.0%). The median PFS was 5.6 months (95% CI: 4.4–6.7 months), and PFS rates at 1‐ and 2‐year timepoints were 34.5% and 13.3%, respectively. The median OS was 11.9 months (95% CI: 0.8–23.0 months). Good performance status and responder of previous PD‐(L)1 inhibitor therapy were independent predictors of PFS. Grade 3 or higher toxicities included leukopenia (27.6%), neutropenia (31.0%), peripheral sensory neuropathy (6.9%), increased alanine aminotransferase and aspartate aminotransferase levels (3.4%), and interstitial lung disease (3.4%). Conclusions Nab‐paclitaxel therapy improved ORR after PD‐(L)1 inhibitor treatment failure with a durable response of 13% and acceptable toxicities in patients with advanced NSCLC