Prevalence of cardiovascular disease risk factors among a Nigerian adult population: relationship with income level and accessibility to CVD risks screening

BackgroundIn Nigeria, reports on the prevalence of modifiable cardiovascular disease (CVD) risk factors are scarce. In addition, socio-economic status (SES), an important component of the socioeconomic gradient in CVD and its risk factors has not been clearly elucidated. This study sought to assess the prevalence of CVD risk factors and how the difference in prevalence and accessibility to CVD risk screening across income levels and educational backgrounds contributes to disease diagnosis in rural and urban Nigerian adults.MethodsA cross sectional study was carried out on a sociocultural ethnic group of persons living in rural and urban settings. All participants were aged ≥ 18 years. The WHO STEPS questionnaire was used to document the demographics, history of previous medical check-up or screening, anthropometric and biochemical measurements of the participants. Average income level and educational status were indicators used to assess the impact of SES. Multivariate analyses were performed to assess any difference between the geographical locations and SES indicators, and prevalence of CVD risk factors and access to CVD risk screening.ResultsThe 422 participants (149 males and 273 females) had mean age (± standard deviation) of 38.3 ± 20.5 and 42.9 ± 20.7 years, respectively. Only total cholesterol (p = 0.001), triglyceride (p = 0.005), high density lipoprotein cholesterol (HDL) (p < 0.0001), body mass index (BMI) (p = 0.03) and average income rate (p = 0.01) showed significant difference between gender groups. Overall prevalence of prediabetes (4.9%), diabetes (5.4%), hypertension (35.7%), low HDL (17.8%), hypertriglyceridemia (23.2%), hypercholesterolemia (38.1%) and central obesity of 52.2% was recorded. Except between total cholesterol (p = 0.042) and HDL (p = 0.017), other CVD risk factors did not show a statistical significance across income levels. Participants with ‘university and postgraduate education’ had higher access to blood pressure and blood glucose screening compared to other educational groups; and this showed a statistical significance.ConclusionThis study has shown that a significant number of modifiable CVD risk factors exist in the rural and urban migrants of an adult Nigerian population. While income level did not affect the CVD risk factor prevalence, it did affect accessibility to CVD risk screening. There is a need for access to diagnosis of modifiable risk factors at all levels of society

The point prevalence of respiratory syncytial virus in hospital and community-based studies in children from Northern Australia:studies in a 'high-risk' population

Introduction: Respiratory syncytial virus (RSV) is the leading viral cause of acute lower respiratory infections globally, accounting for high morbidity and mortality burden among children aged less than 5 years. As candidate RSV vaccine trials in pregnant women and infants are underway a greater understanding of RSV epidemiology is now needed, especially in paediatric populations with high rates of acute and chronic respiratory disease. The objective was to identify RSV prevalence in children living in northern Australia, a region with a high respiratory disease burden. Methods: Data were sourced from 11 prospective studies (four hospital and seven community-based) of infants and children with acute and chronic respiratory illnesses, as well as otitis media, conducted between 1996 and 2017 inclusive. The data from northern Australian children in these trials were extracted and, where available and consented, their nasopharyngeal swabs (biobanked at -80°C) were tested by polymerase chain reaction assays for RSV-A and B, 16 other viruses and atypical respiratory bacterial pathogens. Results: Overall, 1127 children were included. Their median age was 1.8 years (interquartile range 0.5-4.9); 58% were male and 90% Indigenous, with 81% from remote communities. After human rhinoviruses (HRV), RSV was the second most prevalent virus (15%, 95% confidence interval (CI) 13-18). RSV prevalence was greatest amongst children aged less than 2 years hospitalised with bronchiolitis (47%, 95%CI 41.4-52.4), with more than two-thirds with RSV aged less than 6 months. In contrast, the prevalence of RSV was only 1-3.5% in other age groups and settings. In onethird of RSV cases, another respiratory virus was also detected. Individual viruses other than RSV and HRV were uncommon (0-9%). Conclusion: Combined data from 11 hospital and communitybased studies of children aged less than 18 years who lived in communities with a high burden of acute and chronic respiratory illness showed that RSV was second only to HRV as the most prevalent virus detected across all settings. RSV was the most frequently detected virus in infants hospitalised with bronchiolitis, including those aged less than 6 months. In contrast, RSV was uncommonly detected in children in community settings. In northern Australia, effective maternal and infant RSV vaccines could substantially reduce RSV bronchiolitis-related hospitalisations, including admissions of Indigenous infants from remote communities.</p

Hearing loss prevalence and years lived with disability, 1990–2019: findings from the Global Burden of Disease Study 2019

Background Hearing loss affects access to spoken language, which can affect cognition and development, and can negatively affect social wellbeing. We present updated estimates from the Global Burden of Disease (GBD) study on the prevalence of hearing loss in 2019, as well as the condition's associated disability. Methods We did systematic reviews of population-representative surveys on hearing loss prevalence from 1990 to 2019. We fitted nested meta-regression models for severity-specific prevalence, accounting for hearing aid coverage, cause, and the presence of tinnitus. We also forecasted the prevalence of hearing loss until 2050. Findings An estimated 1·57 billion (95% uncertainty interval 1·51–1·64) people globally had hearing loss in 2019, accounting for one in five people (20·3% [19·5–21·1]). Of these, 403·3 million (357·3–449·5) people had hearing loss that was moderate or higher in severity after adjusting for hearing aid use, and 430·4 million (381·7–479·6) without adjustment. The largest number of people with moderate-to-complete hearing loss resided in the Western Pacific region (127·1 million people [112·3–142·6]). Of all people with a hearing impairment, 62·1% (60·2–63·9) were older than 50 years. The Healthcare Access and Quality (HAQ) Index explained 65·8% of the variation in national age-standardised rates of years lived with disability, because countries with a low HAQ Index had higher rates of years lived with disability. By 2050, a projected 2·45 billion (2·35–2·56) people will have hearing loss, a 56·1% (47·3–65·2) increase from 2019, despite stable age-standardised prevalence. Interpretation As populations age, the number of people with hearing loss will increase. Interventions such as childhood screening, hearing aids, effective management of otitis media and meningitis, and cochlear implants have the potential to ameliorate this burden. Because the burden of moderate-to-complete hearing loss is concentrated in countries with low health-care quality and access, stronger health-care provision mechanisms are needed to reduce the burden of unaddressed hearing loss in these settings

Farmers patronage level of informal credit in Imo State: implications for efficient formal and informal financial linkage and rural development

Low agricultural productivity in Imo State could be attributed to poor grass root financial development. Farmers are increasingly marginalized by the conventional banks especially in credit delivery and this study is designed to facilitate a formal and informal credit linkage format. Data were collected from 59 arable crop farmers and 15 informal financial agencies and analyzed using both descriptive statistics and ordinary least square estimates. The result showed that 52% of the farmers were females and 42% of the total respondents had acquired secondary education with a mean farming experience of 16 years. About 81.4% of them inter planted cassava with either maize or beans. It was shown that more than 93.2% of the farmers belonged to Town Union/Age Grade with either Cooperative or Esusu or both, access financial assistance from them. The highest credit disbursement could be accessed from the Town Union with a total of and a mean value of 1,469,000 and N26, 709 respectively, which ranges from N9, 000 to N60, 000 per annum. Farmers mean patronage of informal credit services was as high as 71.2%, thus explaining the reason for low status of rural development in the state. The low patronage of Town Union despite its high membership was due to their involvement in other community development projects. Educational level of the farmers, framing experience, household size and social capital had direct but significant effect on the increasing rate of farmer’s patronage of informal credit, while high interest rate reduced the rate of patronage of informal credit in the area. The study therefore suggested that the grass root financial development should facilitate development using the existing social mobility such as social capital and enhanced education.Keywords: Patronage, formal and informal credit, financial linkage, rural development

HIV/AIDS knowledge and attitudes assessment among women of child-bearing age in South Sudan: Findings from a Household Survey.

This study assessed the determinants that shape HIV knowledge and attitudes among South Sudanese women by analysing a Multiple Indicator Cluster Survey collected from 9,061 women in 9,369 households. Generalised linear mixed model regression was performed. Fifty percent of respondents were aware of HIV/AIDS, with 21% and 22% exhibiting good knowledge and positive attitudes towards people with HIV/AIDS, respectively. When controlled for individual and community-level variables, younger women (AOR = 1.28, 95% CI: 1.01-162), women with primary (AOR = 2.19; 95% CI: 1.86-2.58) and secondary (AOR = 4.48; 95% CI: 3.38-5.93) education, and those living in urban areas (AOR = 1.40; 95% CI: 1.12-1.76) had significantly good knowledge. Women in the richer (AOR = 1.60; 95% CI: 1.08-2.36) and the richest (AOR = 2.02; 95% CI: 1.35-3.02) wealth quintiles had significant positive attitudes towards people with HIV/AIDS. Well-designed social and behavioural campaigns targeting uneducated women and those living in rural and remote settings will enhance knowledge of perceived risk, awareness, and ability to carry out preventive behaviours

Artificial neural network model for cost optimization in a dual-source multi-destination outbound system

Cost optimization is one of the most important issues in distribution operations of any manufacturing system. Most real life problems are non-deterministic polynomial-time hard, and solving such problems are quite challenging. Managing Dual Source multi-destination Inventory system is extensively more difficult than managing a single source multi-destination inventory structure. Undesirably, most managers rely on traditional method while making allocation decision. There is need for efficient and robust computational algorithm. This study emphasizes the importance of creative algorithm, artificial neural network (ANN) in decision-making. ANN model was applied to a double-source multi-destination system in a paint manufacturing company. The accuracy of the model was evaluated using mean square error and correlation coefficient (®values for actual and predicted standards. ANN Feed-Forward Back-Propagation learning with sigmoid transfer function [3–10–1–1] was considered using 74% of available data for training and 26% for testing and validation. The result showed that the proposed method (ANN) outperforms the classical method in use. Approximately 17% of the current operational cost was saved using the soft computing technique

The impact of cultural limitations, local beliefs and practices on emerging parasitic diseases in tropical Africa

In tropical African communities, the scourge of emerging parasitic diseases such as urinary schistosomiasis, ascariasis, malaria, chagas disease, leishmaniasis, trachoma, trichiuriasis, taeniasis, dracunculiasis, sleeping sickness, filariasis among others, causes tremendous pain, suffering and eventually death. The pattern of transmission of these emerging parasitic diseases in a cultural setting is regulated by a complete interplay of human factors including those, which act as effective barriers to the spread of the disease and others that enhance its promotion. A better understanding of these factors especially clinical signs, symptoms and their manifestations is necessary in determining interventions that could upset the established culture - parasite relationship in favor of limiting the spread of the disease or bringing about a cessation in its transmission. This is needed for forward planning of effective control strategies. This study highlights some of the identified cultural limitations/human behavioral patterns mitigating against prevention and control measures of diseases, discusses the nature and impact of local beliefs and some peculiar practices on emerging parasitic diseases in tropical Africa. Health education is identified as a major key factor in erasing negative beliefs, cultural practices as well as behavioral patterns, which enhances the emergence of parasitic diseases in the tropical environment. International Journal of Natural and Applied Sciences Vol. 1(2) 2005: 153-16