Engineering the substrate specificity of toluene degrading enzyme XylM using biosensor XylS and machine learning

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New auroral spectrometer using an acousto-optic tunable filter

This paper reports the performance and capability of a newly developed zenith spectrometer (for measurements of airglow and aurora) that uses an acousto-optic tunable filter (AOTF). The AOTF can scan the pass-band of the spectrometer between 450 and 700 nm with a bandwidth of 2-3 nm by changing the RF driver frequency from 180 to 100 MHz. The absolute sensitivity of the spectrometer is ～0.1-1.5 counts/Rayleigh/s per spectral step. The spectrometer is fully automated. The O I (557.7 nm) airglow line can be clearly identified in test observations of midlatitude airglow performed at Shigaraki Observatory, Japan. Based on an estimate of the signal-to-noise ratio, we conclude that the full auroral spectrum (450-700) nm can be measured by the AOTF spectrometer with a time resolution of ～100 s and a signal-to-noise ratio of ～100 for an auroral emission intensity of 10 kR. An example of the auroral spectra is shown for observations made at Syowa Station in Antarctica

Vasospastic angina resulting in sudden cardiac arrest, initially misdiagnosed as a psychiatric disorder

AbstractA 51-year-old-woman with a history of ablation therapy due to Wolff–Parkinson–White syndrome had been suffering from ambiguous chest pain, prompting investigation by several cardiologists. After being dissatisfied with a psychiatric disorder diagnosis, she was admitted to our hospital for further investigation. She lost her consciousness due to a sudden cardiac arrest shortly after admission. A provocation test indicated vasospastic angina associated with a diffuse spastic pattern of her left anterior descending artery.<Learning objective: This case demonstrates that implantation of a cardioverter defibrillator may be avoided if the angiographic pattern of the vasospasm is recognized, the condition is correctly diagnosed, and appropriate medications are prescribed.