A systematic review and appraisal of methods of developing and validating lifestyle cardiovascular disease risk factors questionnaires

Background: Well developed and validated lifestyle cardiovascular disease (CVD) risk factors  questionnaires is the key to obtaining accurate information to enable planning of CVD prevention program which is a necessity in developing countries. We conducted this review to assess methods and processes used for development and content validation of lifestyle CVD risk factors questionnaires and possibly  develop an evidence based guideline for development and content validation of lifestyle CVD risk factors questionnaires.Materials/methods: Relevant databases at the Stellenbosch University library were searched for  studies conducted between 2008 and 2012, in English language and among humans. Using the following databases; pubmed, cinahl, psyc info and proquest. Search terms used were CVD risk factors, questionnaires, smoking, alcohol, physical activity and diet.Results: Methods identified for development of lifestyle CVD risk factors were; review of literature either systematic or traditional, involvement of expert and /or target population using focus group   discussion/interview, clinical experience of authors and deductive reasoning of authors. For validation, methods used were; the involvement of expert panel, the use of target population and factor analysis.Conclusion: Combination of methods produces questionnaires with good content validity and other psychometric properties which we consider good.Keywords: systematic review, lifestyle cardiovascular disease, risk factors questionnaire

Cardiomyopathies in Sub-Saharan Africa: Hypertensive Heart Disease (Cardiomyopathy), Peripartum Cardiomyopathy and HIV-Associated Cardiomyopathy

Cardiomyopathy is an important cause of cardiac-related morbidity and mortality in sub-Saharan Africa. Dilated cardiomyopathy is responsible for 20–30% of adult heart failure (HF) in the region. It is only second to hypertensive heart disease as etiological risk factor for HF in many parts of the continent. The aim of the chapter is to review the current epidemiology, clinical features, management, and prognosis of hypertensive heart disease, peripartum cardiomyopathy, and HIV-associated cardiomyopathy in sub-Saharan Africa

Comparative Efficacy of Neem Seed Extract with Carbofuran in the Management of African Rice Gall Midge, Orseolia oryzivora Harris and Gagne (Diptera: Cecidomyppdae)

African rice gall midge (AfRGM) Orseolia oryzivora Harris and Gagné is one of the major insect pests of rice in Africa. The dominant pest control strategy in the tropical rice over the past few decades has been in the use of synthetic insecticide. Unfortunately synthetic insecticides have not given the desired results in the management of African rice gall midge, in addition to the side effects of synthetic insecticides on the environment. In order to alleviate the growing public concerns regarding the effects of synthetic pesticides on human health and environmental impact, much attention has been given to botanicals pesticides in the recent decades. Consequently, this study was conducted to determine the efficacy of neem seed extracts in the management of AfRGM compare to carbofuran during 2006/ 2007 farming seasons at two eco-sites in Nigeria. Moreover the effect of the treatments on grain yields was carried out to determine its efficiency. Results showed that the plots treated with neem seed kernel extracts significantly (P < 0.001) reduced AfRGM damage compared to untreated check, and was not statistically different from those plots treated with synthetic pesticide across the levels and seasons. The highest infestation was recorded in the untreated control plots throughout the experimental periods. There was also significant (P < 0.05) increase in number of productive tillers in the treated plots, which significantly increased rice grain yield than in the control plots. The results therefore suggest that the application of neem seed extracts could serve as a suitable alternative to synthetic insecticides in the management of AfRGM. More so the extract has the potential to increase rice grain yield without the disruption of the agro-ecosystem. Keyword: Plant extract, Carbofuran, Orseolia oryzivora control, grain yield

Review of the Fertility Status of the Wetlands of the Lower Anambra River Basin for Sustainable Crop Production.

The Wetlands of the Lower Anambra River Basin have been subjected to continuous crop production for a long time without adequate fertility restoration strategies. There was therefore the need to re-evaluate the soils health for sustainable crop production. Soil samples were   collected from the different zones of the study area and used to evaluate the soils texture, and physico- chemical properties. The results revealed that bulk density ranged from 1.3gcm-3 to 1.74gcm-3 with a mean value of 1.50gcm-1, while the hydraulic conductivity values ranged from 48.0 to 120.0 cm/hr with a mean value of 72.7cm/hr.  The moisture content of the soils was as high as 47.72 to 59.11%.  The soils were generally strongly acidic, ranging from pH 3.39 to 4.94. The organic matter status was generally low, ranging from 0.7 to 2.53 %. The Cation exchange capacity (CEC) was also generally low. The soils suffer multi-nutrient deficiencies. Total N was generally low in all the zones <0.15%, with a range of 0.042 to 0.14%. The available phosphorus in most of the soils were low (<15.0mg kg ), the exchangeable K had a range of 0.077 to 0.246 Cmol/kg. The exchangeable Ca had a range of 1.60 to 5.20 Cmol/kg, low to medium level, while Mg and Na had ranges of 0.80 to 3.20 Cmol/kg and 0.044 to 0.139 Cmol/kg respectively. It was concluded that the soils require conventional to minimum tillage, use of organic manures, judicious use of organic residues, liming, Bio-fertilizers and NPK fertilizers in other to sustain the soil for intensive crop production. Keywords: Soil fertility; Wetlands; Anambra river basin; Crop production

Addressing the Emerging Issues of Xenophobic Attack and Human Rights Violations in South Africa: Adopting a Human Rights-Based Approach

Human Rights abuses in South Africa occasioned by xenophobic attacks in South Africa had occurred intermittently for over a decade despite the hue and cry against xenophobia. Driven primarily by efforts to protect human life and overcome the challenges of xenophobia, some international human rights organisations expressed their views on the curtailment of human rights abuses perpetrated in South Africa. Contextually, South- Africa has notable human rights organisations, yet human rights abuses happen through xenophobic attacks in some parts of the country. The primary objective of this paper is to identify human rights challenges brought about by xenophobic attacks, including the right to human dignity and the right to life. This methodology adopted in this paper included reference to statutes, internet sources, and newspaper publications. This paper finds, amongst others, that despite the United Nations conventions and other international laws guaranteeing the human rights of all persons, the South African government appeared overwhelmed by the xenophobic attacks in dealing with the situation. This paper made useful recommendations towards preventing future xenophobic attacks and avoiding human rights violations

Effect of Abiotic Factors on the Incidence of African Rice Gall Midge, Orseolia oryzivora and its Parasitism by Platygaster diplosisae and Aprostocetus procerae

African rice gall midge (AfRGM), Orseolia oryzivora is one of the most damaging insect pests of lowland rice in Nigeria in the recent time, and could result in total crop failure in endemic areas. Of all the control measures adopted so far biological control is the most promising. Two parasitoids (Platygaster diplosisae, Hym: Platygastridae and Aprostocetus procerae, Hym: Eulophidae) have been identified with the potential to suppressed AfRGM population. In the current study, we evaluated the effect of abiotic factors (rainfall, relative humidity and temperature) in two eco-sites for two years on the incidence of AfRGM, and on the efficiency of the two parasotioids in the management of AfRGM. The incidence of AfRGM was significantly influenced by abiotic factors (rainfall, relative humidity and temperature). The percentage infestation increased with increase in rainfall and relative humidity. The trend was similar at both locations with the highest infestation recorded in October, and decreased in November. At both locations, percentage tiller infestation was greater in the rainy season of 2006 with more frequent rains than in 2007, with highest infestation recorded at Edozhigi in both years. Percentage parasitisms by the two parasitoids were found to have significant correlation with the abiotic factors. Heavy rains and high humidity significantly reduced the efficiency of the two parasitoids. On the contrast, the population and efficiency of the parasitoids were observed to increase with reducing rainfall, RH, but increasing temperature thus increasing the efficiency of the parasitoids later in the season with up to 70% parasitism when combined, with P. diplosisae dominating the field. The results suggest that abiotic factors played significant role on the incidence of AfRGM and the efficiency of these parasitoids and should be considered in the adoption of these parasitoids as bio-control agents of AfRGM. Keywords: Orseolia oryzivora, Platygaster diplosisae, Aprostocetus procerae, abiotic factor

Effect of Different Sources of Heat on Nutritional Composition of Tilapia Fish (Oreochromis niloticus)

A study was conducted to investigate the effect of traditional smoking methods on fresh tilapia fish (Oreochromis niloticus). For this purpose, proximate, mineral and amino acid compositions of tilapia fish smoked with sawdust, rice bran, melon husk and electric oven (control) heat treatments were determined using standard analytical technique. The results showed that crude protein content (%) ranged between 55.10 to 64.16% with the highest value recorded in sample smoked with rice bran heat treatment while crude fat had the highest value (18.10%) also in rice bran smoked sample. Sodium was found to be more abundant in all the samples (5.75 – 10.10 mg/100g) compared with magnesium (5.45 – 9.15 mg/100g), potassium (4.55 – 6.45 mg/100g) and phosphorus (4.70 – 6.00 mg/100g) while the least abundant mineral was chromium (0.05 – 0.15 mg/100g). The harmful metals such as cadmium and lead were not at detectable range of atomic absorption spectrophotometer (AAS). The amino acid profile revealed that only Oreochromis niloticus fish sample smoked with sawdust enhanced the contents of total amino acid (TAA), total essential amino acid (TEAA) and total sulphur amino acid (TSAA) by 3.77, 3.95 and 7.03%, respectively while melon husk and rice bran heat treatments reduced TAA, TEAA and TSAA. The limiting amino acid (LAA) for all the samples with different heat treatments was Ile except sample smoked with rice bran which has Val as LAA. Generally, all the smoked samples contained nutritionally useful quantities of total essential amino acids. Keywords: Oreochromis niloticus, agricultural wastes, smoke, proximate, amino acids

Graves’ disease presenting as paranoid schizophrenia in a Nigerian woman: a case report

Paranoid syndromes in Graves’ disease are rare. The true incidence is lacking. Most reports have emanated from developed countries where medical investigations are readily available. No report of such has emanated from Nigeria. We report a 43-year-old female Nigerian with Graves’ disease associated with paranoid schizophrenia and review the literature

Economic burden of heart failure: investigating outpatient and inpatient costs in abeokuta, southwest Nigeria

Background: Heart failure (HF) is a deadly, disabling and often costly syndrome world-wide. Unfortunately, there is a paucity of data describing its economic impact in sub Saharan Africa; a region in which the number of relatively younger cases will inevitably rise. Methods: Heath economic data were extracted from a prospective HF registry in a tertiary hospital situated in Abeokuta, southwest Nigeria. Outpatient and inpatient costs were computed from a representative cohort of 239 HF cases including personnel, diagnostic and treatment resources used for their management over a 12-month period. Indirect costs were also calculated. The annual cost per person was then calculated. Results: Mean age of the cohort was 58.0±15.1 years and 53.1% were men. The total computed cost of care of HF in Abeokuta was 76, 288,845 Nigerian Naira (US$508, 595) translating to 319,200 Naira (US$2,128 US Dollars) per patient per year. The total cost of in-patient care (46% of total health care expenditure) was estimated as 34,996,477 Naira (about 301,230 US dollars). This comprised of 17,899,977 Naira- 50.9% ($US114,600) and 17,806,500 naira −49.1$US118,710) for direct and in-direct costs respectively. Out-patient cost was estimated as 41,292,368 Naira ($US 275,282). The relatively high cost of outpatient care was largely due to cost of transportation for monthly follow up visits. Payments were mostly made through out-of-pocket spending. Conclusion: The economic burden of HF in Nigeria is particularly high considering, the relatively young age of affected cases, a minimum wage of 18,000 Naira ($US120) per month and considerable component of out-of-pocket spending for those affected. Health reforms designed to mitigate the individual to societal burden imposed by the syndrome are required