Sex differences in distress from infidelity in early adulthood and in later life:A replication and meta-analysis of Shackelford et al. (2004)

Shackelford and colleagues (2004) found that men, compared to women, are more distressed by sexual than emotional infidelity, and this sex difference continued into older age. We conducted four high-powered replications (total N = 1,952) of this effect and found different results. A meta-analysis of original and replication studies finds the sex difference in younger samples (though with a smaller effect size), and no effect among older samples. Furthermore, we found attitude toward uncommitted sex to be a mediator (although not consistently in the same direction) between participant sex and relative distress between sexual and emotional infidelity. We hypothesize that the discrepancies between the original and replication studies may be due to changing cultural attitudes about sex across time. Confirming this speculative interpretation requires further investigation. Keywords: evolutionary psychology, human nature, sex differences, cultural differences, replicatio

Aeroacoustic and flow assessments of the poro-serrated trailing edges

This paper reports an aeroacoustic study of a NACA0012 aerofoil with a nonflat plate type serrated trailing edge, and a number of Poro-Serrated trailing edge devices that contain porous materials of various air flow resistances at the gaps between adjacent members of the serrated sawtooth. Free field noise measurements were performed inside an aeroacoustic wind tunnel facility, where the range of jet speeds was between 20 ms-1 and 60 ms-1. Flow measurements were also conducted in the same facility for the very near wake. The main objective of this work is to determine whether multiple-mechanisms on the broadband noise reduction can co-exist on a poro-serrated trailing edge. The results demonstrate that having low flow resistivity at the sawtooth gaps could not completely suppress the vortex shedding tone at low frequency, but it can achieve reasonably well broadband noise reduction at high frequency. With high flow resistivity at the sawtooth gaps, the denser porous material almost renders the poro-serrated trailing edge to becoming a straight trailing edge again, thus undermining the serration effect and causing a drop in the noise performance. The optimal range of flow resistivity for the poro-serrated trailing edge is found to be around 10 kN.s.m-4, where it can even perform slightly better than the conventional serrated trailing edge in terms of the turbulent broadband noise reduction while still completely suppresses the vortex shedding noise. From the analysis of the wake data, the overall drag force will not increase when a poro-serrated trailing edge is used.The EPSRC Impact Acceleration Account – Readiness in the United Kingdom

Having co-morbid cardiovascular disease at time of cancer diagnosis:Already one step behind when it comes to HRQoL?

Background The relation between cardiovascular disease (CVD) present at the time of cancer diagnosis and Health-Related Quality of Life (HRQoL) assessed years after cancer diagnosis has – to our knowledge – not been studied. The objective is, therefore, to examine the relation between co-morbid CVD at cancer diagnosis and HRQoL among cancer survivors diagnosed with colorectal, thyroid, prostate, endometrium, ovarian cancer, melanoma, (non-)Hodgkin lymphoma, chronic lymphocytic leukemia (CLL), or multiple myeloma (MM) in an exploratory population-based cross-sectional study. Material and methods Analyses were performed on combined data sets from the PROFILES and Netherlands Cancer Registry (NCR). Data on co-morbid CVD at cancer diagnosis was extracted from the NCR. HRQoL was measured via PROFILES at a median of 4.6 years after cancer diagnosis. General Linear Model Analyses were run for the total group of cancer survivors and for each malignancy. Results In total, 5930 cancer survivors (2281 colorectal, 280 thyroid, 1054 prostate, 177 endometrium, 389 ovarian cancer, 212 melanoma, 874 non-Hodgkin and 194 Hodgkin lymphoma, 242 CLL, and 227 MM survivors) were included. For the total group, survivors who had a CVD at cancer diagnosis (n = 1441, 23.4%) reported statistically significant and clinically important lower scores on global QoL and physical functioning and higher scores for dyspnea (p < .05) compared to those without CVD. Co-morbid CVD at cancer diagnosis was negatively related to global QoL, the five functional scales and the symptoms fatigue and dyspnea across most malignancies (i.e., colorectal, and prostate cancer, non-Hodgkin lymphoma, ovarium cancer, melanoma, and CLL). No significant relations were found among thyroid and endometrium cancer, Hodgkin lymphoma and MM survivors, likely due to small numbers. Conclusion In conclusion, co-morbid CVD at cancer diagnosis was negatively related to HRQoL, especially to global QoL, physical and role functioning, and the symptoms fatigue and dyspnea

Naar een nieuwe regeling voor beslag op gegevensdragers

Effective Protection of Fundamental Rights in a pluralist worl

Disease management with home telemonitoring aimed at substitution of usual care in the Netherlands: Post-hoc analyses of the e-Vita HF study

BACKGROUND: Home telemonitoring in heart failure (HF) patients may reduce workload of HF nurses by reducing face-to-face contacts. The aim of this study is to assess whether telemonitoring as a substitution could have negative effects as expressed by less reduction in circulating natriuretic peptide levels between baseline and one-year of follow up compared to usual care. METHODS: A post-hoc analysis of the e-Vita HF trial, a three-arm parallel randomized trial conducted in stable HF patients. Patients were randomized into three arms: (i) usual HF outpatient care, (ii) usual care combined with the use of the website heartfailurematters.org, and (iii) telemonitoring (e-Vita HF platform) instead of face-to-face consultations. Mixed linear model analyses were applied to assess differences in the N-terminal prohormone of brain natriuretic peptide (NT-proBNP) levels between the three arms over a year. RESULTS: A total of 223 participants could be included (mean age 67.1 ± 10.1 years, 27% women, New York Heart Association class I–IV; 39%, 38%, 14%, and 9%). The mean left ventricular ejection fraction was 35 ± 10%. The median of routine face-to-face contacts over a year was 1.0 lower (2.0 vs. 3.0) in the third arm compared with usual care. Median NT-proBNP levels did not significantly differ between the three arms. CONCLUSION: In stable and optimally treated HF patients, telemonitoring causing a reduction of routine face-to-face contacts seems not to negatively affect hemodynamic status as measured by NT-proBNP levels over time

The future of data driven investigations in light of the Sky ECC operation

The Sky elliptic-curve cryptography (Sky ECC) operation is a prime example of a data-driven investigation. The collection of approximately 1 billion messages from 70,000 phones paved the way for hundreds of criminal investigations, resulting in numerous convictions in the Netherlands and Belgium alone. This article addresses how the Sky ECC operation interferes with the right to privacy and the right to a fair trial. We examine whether or not, and on what terms, there is a future for data-driven criminal investigations. Our main research question is therefore how data-driven criminal investigations can be (better) regulated in order to be in line with case law of the European Court of Human Rights. To answer the research question, the main characteristics and legal criteria for data-driven investigation are identified. These criteria derived from the right to privacy and the right to a fair trial. Finally, we examine the impact of a violation of these criteria for the use of evidence in criminal proceedings. The research uncovers a disconnection between data protection regulations and criminal procedural law. It highlights that practitioners concentrate primarily on the collection phase, governed by criminal procedural law, whereas the most urgent questions relate to the respect of data protection law and the right to a fair trial. This finding suggests an ongoing discourse relating to the transparency of data-driven criminal operations like Sky ECC and the need to address concerns regarding the reliability of evidence