117 research outputs found
Cosmological parameter estimation with large scale structure and supernovae data
Most cosmological parameter estimations are based on the same set of
observations and are therefore not independent. Here, we test the consistency
of parameter estimations using a combination of large-scale structure and
supernovae data, without cosmic microwave background (CMB) data. We combine
observations from the IRAS 1.2 Jy and Las Campanas redshift surveys, galaxy
peculiar velocities and measurements of type Ia supernovae to obtain
h=0.57_{-0.14}^{+0.15}, Omega_m=0.28+/-0.05 and sigma_8=0.87_{-0.05}^{+0.04} in
agreement with the constraints from observations of the CMB anisotropies by the
WMAP satellite. We also compare results from different subsets of data in order
to investigate the effect of priors and residual errors in the data. We find
that some parameters are consistently well constrained whereas others are
consistently ill-determined, or even yield poorly consistent results, thereby
illustrating the importance of priors and data contributions.Comment: (1) Astrophysics Group, Cavendish Laboratory, Cambridge Unviersity,
UK (2) Dipartimento di Fisica, Universita di Roma "La Sapienza", Ital
Distinguishing among Scalar Field Models of Dark Energy
We show that various scalar field models of dark energy predict degenerate
luminosity distance history of the Universe and thus cannot be distinguished by
supernovae measurements alone. In particular, models with a vanishing
cosmological constant (the value of the potential at its minimum) are
degenerate with models with a positive or negative cosmological constant whose
magnitude can be as large as the critical density. Adding information from CMB
anisotropy measurements does reduce the degeneracy somewhat but not
significantly. Our results indicate that a theoretical prior on the preferred
form of the potential and the field's initial conditions may allow to
quantitatively estimate model parameters from data. Without such a theoretical
prior only limited qualitative information on the form and parameters of the
potential can be extracted even from very accurate data.Comment: 15 pages, 5 figure
First results from the Very Small Array -- IV. Cosmological parameter estimation
We investigate the constraints on basic cosmological parameters set by the
first compact-configuration observations of the Very Small Array (VSA), and
other cosmological data sets, in the standard inflationary LambdaCDM model.
Using a weak prior 40 < H_0 < 90 km/s/Mpc and 0 < tau < 0.5 we find that the
VSA and COBE_DMR data alone produce the constraints Omega_tot =
1.03^{+0.12}_{-0.12}, Omega_bh^2 = 0.029^{+0.009}_{-0.009}, Omega_cdm h^2 =
0.13^{+0.08}_{-0.05} and n_s = 1.04^{+0.11}_{-0.08} at the 68 per cent
confidence level. Adding in the type Ia supernovae constraints, we additionally
find Omega_m = 0.32^{+0.09}_{-0.06} and Omega_Lambda = 0.71^{+0.07}_{-0.07}.
These constraints are consistent with those found by the BOOMERanG, DASI and
MAXIMA experiments. We also find that, by combining all the recent CMB
experiments and assuming the HST key project limits for H_0 (for which the
X-ray plus Sunyaev--Zel'dovich route gives a similar result), we obtain the
tight constraints Omega_m=0.28^{+0.14}_{-0.07} and Omega_Lambda=
0.72^{+0.07}_{-0.13}, which are consistent with, but independent of, those
obtained using the supernovae data.Comment: 10 pages, 6 figures, MNRAS in pres
Interacting Ghost Dark Energy in Non-Flat Universe
A new dark energy model called "ghost dark energy" was recently suggested to
explain the observed accelerating expansion of the universe. This model
originates from the Veneziano ghost of QCD. The dark energy density is
proportional to Hubble parameter, , where is a
constant of order and is
QCD mass scale. In this paper, we extend the ghost dark energy model to the
universe with spatial curvature in the presence of interaction between dark
matter and dark energy. We study cosmological implications of this model in
detail. In the absence of interaction the equation of state parameter of ghost
dark energy is always and mimics a cosmological constant in the
late time, while it is possible to have provided the interaction is
taken into account. When , all previous results of ghost dark energy in
flat universe are recovered. To check the observational consistency, we use
Supernova type Ia (SNIa) Gold sample, shift parameter of Cosmic Microwave
Background radiation (CMB) and the Baryonic Acoustic Oscillation peak from
Sloan Digital Sky Survey (SDSS). The best fit values of free parameter at
confidence interval are: ,
and . Consequently
the total energy density of universe at present time in this model at 68% level
equates to .Comment: 19 pages, 9 figures. V2: Added comments, observational consequences,
references, figures and major corrections. Accepted for publication in
General Relativity and Gravitatio
Vector field as a quintessence partner
We derive generic equations for a vector field driving the evolution of flat
homogeneous isotropic universe and give a comparison with a scalar filed
dynamics in the cosmology. Two exact solutions are shown as examples, which can
serve to describe an inflation and a slow falling down of dynamical
``cosmological constant'' like it is given by the scalar quintessence. An
attractive feature of vector field description is a generation of ``induced
mass'' proportional to a Hubble constant, which results in a dynamical
suppression of actual cosmological constant during the evolution.Comment: 14 pages, LaTeX file, iopart class, discussion extended, reference
adde
Haploinsufficiency and reduced expression of genes localized to the 8p chromosomal region in human prostate tumors
Cytogenetic and molecular studies have suggested that deletion or rearrangement of sequences that map to the short arm of chromosome 8 may be permissive for tumorigenesis in several organ systems, and in human prostate tumors in particular. In this study, we hypothesized that genes deleted for one copy and localized to the 8p chromosomal region may be transcriptionally down-regulated or ablated in affected human prostate tumor tissues. To test this hypothesis, we used cDNA microarray analysis to determine the transcriptional profiles for 259 transcribed sequences mapping to the 8p chromosomal region for seven human prostate tumor xenografts, completely characterized for numerical and structural alterations on chromosome 8, and five normal human prostate tissues. These experiments identified 33 genes differentially expressed between normal and malignant prostate tissues, the majority of which (28/33, 85%) were transcriptionally down-regulated in malignant compared to normal human prostate tissues. These findings, that haploinsufficiency and transcriptional down-regulation for genes mapping to 8p are largely coincident in human prostate tumors, should provide a powerful tool for the identification of tumor-suppressor genes associated with human prostate cancer initiation and progression. © 2003 Wiley-Liss, Inc.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/35134/1/10226_ftp.pd
How do parents of children with juvenile idiopathic arthritis (JIA) perceive their therapies?
<p>Abstract</p> <p>Background</p> <p>Complementary and alternative medical (CAM) therapies are commonly used by pediatric patients with chronic medical conditions. Little is known about parents' perceptions of these therapies. This study describes the views of parents of patients with juvenile idiopathic arthritis (JIA) regarding conventional and CAM therapies.</p> <p>Methods</p> <p>Parents of children with JIA seen at a pediatric rheumatology clinic were surveyed between June 1 and July 31, 2007. Questionnaires asked about patients' use of over 75 therapies in the past 30 days, their perceived helpfulness (0 = not helpful; 3 = very helpful), perceived side effects (0 = none; 3 = severe), and whether each therapy would be recommended to other patients with JIA (Yes, No, Not sure).</p> <p>Results</p> <p>Questionnaires were returned by 52/76 (68%) parents; patients' average age was 10.9 years and 87% were Caucasian. Medications were used by 45 (88%) patients; heat (67%) and extra rest (54%) were also commonly used. CAM therapies were used by 48 (92%), e.g., massage (54%), vitamins and other supplements (54%), avoiding foods that worsened pain (35%) and stress management techniques (33%). Among the therapies rated by 3 or more parents, those that scored 2.5 or higher on helpfulness were: biologic medications, methotrexate, naproxen, wheelchairs, orthotics, heat, vitamins C and D, music, support groups and prayer. CAM therapies had 0 median side effects and parents would recommend many of them to other families.</p> <p>Conclusion</p> <p>JIA patients use diverse therapies. Parents report that many CAM therapies are helpful and would recommend them to other parents. These data can be used in counseling patients and guiding future research.</p
Mechanical Properties of Dual-Cured Resin Luting Agents for Ceramic Restoration
Purpose: The aim of the present study was to evaluate the mechanical properties including surface hardness, flexural strength, and flexural modulus of two dual-cured resin luting agents (New Resin Cement [NRC] and Variolink II [VLII]) irradiated through four different thickness of leucite ceramics (0, 1, 2, and 3 mm) and their shear bond strength to zirconia ceramic (Cercon) using each ceramic primer. Materials and Methods: Knoop hardness was measured on a thin layer of resin luting agent on the ceramic surface. Three-point bending tests were performed after 24 h storage at 37°C. Two different-shaped zirconia ceramic specimens with or without sandblasting with alumina were treated with each primer. The specimens were then cemented together with each resin luting agent. Half of the specimens were stored in water at 37°C for 24 h and the other half were thermocycled 5,000 times. Results: VLII revealed statistically higher Knoop hardness and flexural modulus than NRC for each thickness of ceramic. No significant differences in flexural strength were observed between VLII and NRC for each ceramic spacer. Reduction of the mechanical properties with increase of ceramic thickness varied for each property. However, these properties were similar between the two materials. Blasting with alumina was significantly effective for increasing shear bond strength of both resin luting agents before and after thermal cycling. The use of New Ceramic Primer showed the highest shear bond strength and maintained bond durability after 5,000 thermocycles. Conclusion: Mechanical properties of NRC dual-cured resin luting agent appear adequate for ceramic restorations.This is an electronic version of an Article published in Journal of Prosthodontics 16(5): 370-376, 2007
The CMB power spectrum out to l=1400 measured by the VSA
We have observed the cosmic microwave background (CMB) in three regions of
sky using the Very Small Array (VSA) in an extended configuration with antennas
of beamwidth 2 degrees at 34 GHz. Combined with data from previous VSA
observations using a more compact array with larger beamwidth, we measure the
power spectrum of the primordial CMB anisotropies between angular multipoles l
= 160 - 1400. Such measurements at high l are vital for breaking degeneracies
in parameter estimation from the CMB power spectrum and other cosmological
data. The power spectrum clearly resolves the first three acoustic peaks, shows
the expected fall off in power at high l and starts to constrain the position
and height of a fourth peak.Comment: 6 pages with 5 figures, MNRAS in press (minor corrections
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