19 research outputs found
The role of DNA microarrays in Toxoplasma gondii research, the causative agent of ocular toxoplasmosis
Get PDFOcular toxoplasmosis, which is caused by the protozoan parasite Toxoplasma gondii, is the leading cause of retinochoroiditis. Toxoplasma is an obligate intracellular pathogen that replicates within a parasitophorous vacuole. Infections are initiated by digestion of parasites deposited in cat feces or in undercooked meat. Parasites then disseminate to target tissues that include the retina where they then develop into long-lived asymptomatic tissue cysts. Occasionally, cysts reactivate and growth of newly emerged parasites must be controlled by the host’s immune system or disease will occur. The mechanisms by which Toxoplasma grows within its host cell, encysts, and interacts with the host’s immune system are important questions. Here, we will discuss how the use of DNA microarrays in transcriptional profiling, genotyping, and epigenetic experiments has impacted our understanding of these processes. Finally, we will discuss how these advances relate to ocular toxoplasmosis and how future research on ocular toxoplasmosis can benefit from DNA microarrays
INFLUENZA DEL TIPO DI ADDESTRAMENTO SUI PROBLEMI COMPORTAMETALI DEI CAVALLI DA EQUITAZIONE
No full textTHE SHORT TERM EFFECT OF FOUR STIMULI ON THE BEHAVIOUR AND HEART RATES OF STEREOTYPING AND NON STEREOTYPING GELDINGS
No full textDOES INTERRUPTION IN A ‘WALKING PROGRAM’ CAUSE STRESS IN KENNELLED BEAGLES?
No full textNiagara Falls, New Yor
THE SHORT TIME EFFECT OF A FORAGING DEVICE - EQUIBALLTM - ON THE HEART RATE OF NON-STEREOTYPING AND STEREOTYPING HORSES
No full textA CONCEPTUAL STUDY ABOUT ANIMAL WELFARE AND 'ANIMAL ASSISTED INTERVENTION' PROGRAMS (ZEELAND - THE NETHERLANDS)
No full textRefinement recommendations for intravenous injection and body heat conservation in Mongolian gerbils used in SPECT studies
Get PDFThis paper describes two aspects of Single Photon Emission Computed Tomography (SPECT) which have been refined for use in small animals, as demonstrated by a study on Mongolian gerbils: intravenous injection of radiotracers in the femoral vein and body heat conservation in animals anaesthetized at the time of scanning. Elaborating on recommendations made by other authors, we have combined chemical and physical restraint to optimize injection efficiency as well as to reduce handling time of the animals. Finally, we provide a detailed description of a SPECT compatible water-heated scanning bed, the application of which we believe is not limited to scintigraphic studies
