Hepatic cirrhosis in two young dogs

No abstract available

Bilateral blindness in a dog due to invasion of the optic chiasma by a glioma

A diagnosis of neoplasia involving the optic chiasma of an 8-year-old Labrador Retriever was suggested by the neurological and radiological findings. At post-mortem examination the location of the tumour was confirmed and it was identified as an oligodendroglioma

Plasma progesterone profiles and variation in cyclic ovarian activity throughout the year in indigenous goats in Zimbabwe

Eleven non-pregnant indigenous goats were bled three times a week from 1 June 1988 to 31 May 1989. They were fed hay ad libitum supplemented by concentrates, and housed indoors in single pens until November when the goats were divided between two large pens. Plasma progesterone profiles were used to calculate cycle length: 73.3% (99/135) of cycles with mean length of 22.0±0.3 days were classified as normal (N). N cycles had a mean luteal phase of 17.5±2 days followed by a peri-ovulatory period of 4.5±0.2 days. Cycles greater than 30 days long were classified as extended (E). These had normal length luteal phases followed by basal progesterone for 15.4±0.5 days (n=22) or 38.9±4.1 days (n=10) before the next cycle, giving cycle lengths of 33.6±7 days and 56.3±0.9 days, respectively. Four E cycles (mean length 117.0±30 days) had a persistent corpus luteum followed by basal progesterone of 17.8±5.6 days in duration. The distribution of N versus E cycles varied between animals and was significantly influenced by season (

A toxidez de diversas lantanas para bovinos e ovinos no Brasil The toxicity of diverse lantanas for cattle and sheep in Brazil

Neste estudo sobre a toxidez das lantanas para bovinos e ovinos, verificou-se situação semelhante à que ocorre na Austrália, que nem todas as espécies de Lantana e nem todos os taxa de Lantana camara que ocorrem no Brasil, são tóxicos. Verificou-se, que foram tóxicas as amostras de lantanas procedentes de Boa Vista (RO), Castanhal (PA), Cáceres (MT), Serra Talhada (PE), Cabo Frio e Quatis (RJ) e Canoinhas (SC). Outras amostras procedentes de Cruzeiro do Sul (Acre), Castanhal (PA), Chapada dos Guimarães e Lambari d´Oeste (MT), Jaguaribe (CE), Vitória da Conquista e Wanderley (BA), Vitória (ES), Vassouras, Parati e Itaguaí (RJ) não revelaram toxidez nas doses administradas (40 g/kg). A dose letal das amostras submetidas à experimentação no Brasil foi bastante constante (40 g/kg), com duas exceções: as folhas frescas da lantana procedente de Canoinha (SC) foram muito mais tóxicas (10 g/kg) e as folhas frescas e as dessecadas da lantana de Serra Talhada (PE) foram muito menos tóxicas, pois somente causaram intoxicação não-letal com a dose de 40g/kg/dia administradas durante 30 dias. Históricos sobre a observação de fotossensibilização em bovinos, ligados à ingestão de lantanas foram obtidos em Serra Talhada (PE), Cáceres (MT), Cabo Frio (RJ), Quatis (RJ) e Canoinhas (SC). Verificou-se que não é possível estabelecer uma correlação entre a cor das inflorescências das lantanas e sua toxidez, confirmando a constatação feita na Austrália, que o potencial de intoxicar não está necessariamente relacionada com a cor das flores.<br>Experiments on the toxicity of Lantana spp for cattle and sheep revealed a similar situation as is reported from Australia. Neither all Lantana species nor all varieties which occur in Brazil are poisonous. Lantana samples collected at Boa Vista (Roraima), Castanhal (Pará), Cáceres (Mato Grosso), Serra Talhada (Pernambuco), Cabo Frio and Quatis (Rio de Janeiro), and Canoinhas (Santa Catarina) were toxic. All the other Lantana samples, collected at Cruzeiro do Sul (Acre), Castanhal (Pará), Chapada dos Guimarães and Lambari d'Oeste (Mato Grosso), Jaguaribe (Ceará), Vitória da Conquista and Wanderley (Bahia), Vitória (Espírito Santo), Vassouras, Parati and Itaguaí (Rio de Janeiro) revealed experimentally as non-toxic at a dose of 40g/kg. In all cases the lethal dose was 40 g/kg, with two exceptions: the sample collected at Canoinha (Santa Catarina) was much more toxic (10g/kg) and the one from Serra Talhada (Pernambuco) was much less toxic, as this last sample caused lethal poisoning only at a dosage of 40g/kg/day given during 30 days. Histories about the observation of photosensitization in cattle due to the ingestion of Lantana spp were obtained at Serra Talhada (Pernambuco), Cáceres (Mato Grosso), Cabo Frio and Quatis (Rio de Janeiro), and Canoinhas (Santa Catarina). No correlation could be established between the colour of the flowers of Lantana spp and the toxicity of the plants. This confirms reports from Australia that the toxic potential of the Lantana species is not necessarily related to the colour of their flowers

Alterações oftálmicas associadas à intoxicação experimental por closantel em caprinos Ophthalmic changes associated with the experimental poisoning by closantel in caprine

Alterações oftálmicas foram experimentalmente induzidas em caprinos após superdosagem com o anti-helmíntico closantel. Foram usados cinco caprinos com sete a oito meses de idade, produtos do cruzamento da raça Saanen com a Pardo Alpino. Os animais mostraram sinais de intoxicação entre quatro e cinco dias após a administração do closantel. Os sinais clínicos caracterizaram-se principalmente por distúrbios neurológicos centrais e cegueira. Ao exame clínico, observaram-se midríase bilateral, perda do reflexo pupilar à luz e cegueira bilateral. À oftalmoscopia indireta, foram observadas degeneração aguda de retina e papiledema. As alterações crônicas mostravam disco óptico acinzentado, atrofia de vasos e da retina. Nos fundos tapetal e não-tapetal notavam-se áreas de despigmentação e lesões irregulares castanho-amareladas. As alterações histológicas consistiam em perda dos neurônios da camada ganglionar e das células da camada nuclear interna e externa da retina. As alterações agudas no nervo óptico e na substância branca do encéfalo foram de degeneração espongiforme. As alterações crônicas do nervo óptico caracterizavam-se por extensa necrose e infiltração de células Gitter.<br>Ophthalmic alterations were experimentally induced after overdose with the anthelmintic closantel. Five seven to eight- months-old, Saanen x Alpine caprine were used. The animals showed clinical signs of toxicosis four to five days after the administration of closantel. Clinical signs were primarily characterized by central nervous disturbances and blindness. Clinically, bilateral mydriasis, loss of pupillary light reflex, and blindness were observed. At indirect ophthalmoscopic examination, there was acute retinal degeneration and papilledema. Chronic ocular changes consisted of paleness of the optic disc, vascular atrophy, and retinal atrophy. Areas of pigment loss and irregular yellowish-brown foci were present in the tapetal and non-tapetal fundus. Histological alterations consisted of neuronal loss in the ganglion cell layer and depletion of cells in both the outer and inner nuclear layers of the retina. Acute changes of spongy degeneration were noted in the optic nerve and in the cerebral white matter. Chronic lesions in the optic nerve were characterized by extensive necrosis and infiltration by Gitter cells