(S S,2S,3R)-2-(2-Methyl­propane-2-sulfin­amido)-3-phenyl­butyronitrile

The absolute configuration has been determined for the title compound, C14H20N2OS. Inter­molecular N—H⋯O hydrogen bonds are observed in the crystal packing, forming infinitive one-dimensional chains with the base vector [100]

Review of the governance regulation and the European climate law

Upgrading the EU’s procedural climate governance The mandated reviews of the Governance Regulation and the European Climate Law (ECL) provide a unique opportunity for upgrading the EU’s procedural climate governance. The Governance Regulation (Regulation 2018/1999 on the Governance of the Energy Union and Climate Action) and the ECL (Regulation 2021/1119 on Establishing the Framework for Achieving Climate Neutrality) are the foundational building blocks of procedural EU climate governance. They define first instruments, institutions and processes for developing and implementing substantive EU climate policies that directly address the mitigation of greenhouse gas (GHG) emissions. Procedural climate governance is of pivotal importance for a successful transition to climate neutrality. The long-term, dynamically evolving and crosscutting nature of the “super wicked” climate challenge requires the continuous development and adaptation of climate policies. The increasing contestation of climate policies and rising climate “backlash” reinforce the need to firmly anchor the climate transition in our societal and political systems and hence underline the importance of effective procedural climate governance, i.e. of the “how” of climate policymaking, aiming for accountability, fairness, and inclusivity in decision-making. Against this backdrop, it seems paramount to address existing shortcomings and gaps of procedural EU climate governance to mobilise its potential to the fullest extent possible. 6 key options for upgrading eight major dimensions of procedural EU climate governance: National Energy and Climate Plans (NECPs) and Long-Term Strategies (LTSs) under the Governance Regulation: (a) alignment of NECPs and national LTSs with each other and with other plans and strategies; (b) enhanced and aligned review mechanisms, (c) strengthened support and capacity building, and (d) regular updating of the EU LTS. Climate-neutrality targets: integration into member states’ LTSs under the Governance Regulation, including key accompanying information on how residual emissions are to be balanced, based on independent scientific advice. Public participation, in particular: (a) acknowledgement of the 1998 Aarhus Convention on Access to Information, Public Participation in Decision-making and Access to Justice in Environmental Matters and the right to peaceful assembly; (b) upgrading of public participation in NECPs and national LTSs and of multilevel climate and energy dialogues under Articles 10 and 11 of the Governance Regulation; (c) promotion of innovative means of public participation and deliberation in member states and at EU level; (d) commitment to provide information on how public participation inputs have been integrated into policymaking; (e) provision of support and best-practice guidance; (f) setting up of a consultation structure on EU climate policy and balancing of the composition of advisory bodies. Access to justice (A2J): (a) clarification that acts and omissions of the Commission under these instruments can be challenged under the EU’s Aarhus Regulation; (b) providing for A2J in member states regarding key obligations under the Governance Regulation; and (c) a general commitment to including A2J provisions across EU climate and energy legislation or establishing a related provision in the Governance Regulation itself. Reporting obligations of member states and related review under the Governance Regulation: (a) instituting systematic biennial reviews by the Commission with actionable recommendations; (b) strengthened reporting particularly concerning the social dimension and investment frameworks; and (c) enhancing the transparency of biennial progress reports. Evaluation and response (regarding member-state ambition and progress) under the Governance Regulation: (a) clarification that related Commission recommendations can be challenged under the Aarhus Regulation (see above on A2J); (b) strengthened member state obligations to take corrective action; and (c) cross-compliance restrictions on access to funding in response to persistent lack of ambition or progress. Independent scientific expert advisory bodies under the ECL: (a) further specification of the mandate of the European Scientific Advisory Board on Climate Change; (b) requirement for the European Institutions to explain how the advice received has been taken into account in decision-making; and (c) strengthened guidance for member states to establish national advisory bodies in accordance with best-practice standards. Cross-policy consistency and climate policy integration: (a) elaboration and codification of the principles on Do No Significant Harm (DNSH) and fostering synergy/coherence; and (b) full alignment of economic and investment policies (European Semester, public budgets, relevant national plans and strategies) with climate policy objectives

Gezielter Aufbau von beta-(1-4)-verknüpften Oligomeren der D-Galactose

Beta-(1-4)-verknüpfte Galactooligosaccharide stellen in vielerlei Hinsicht interessante Syntheseziele dar. So ist über die dreidimensionale Struktur der beta-(1-4)-D-Galactane nur wenig bekannt, obwohl diese Polymere als Bestandteil der Pflanzenzellwand auftreten und von einigen Pflanzen sogar als deren Hauptkomponente genutzt werden. Da diese Biomoleküle nur schwierig in Reinform und definierter Kettenlänge zu isolieren sind, wurde im Rahmen dieser Arbeit daher eine effiziente chemische Synthese entsprechender Oligogalactoside entwickelt, die somit erstmals zugänglich gemacht werden konnten. Die Synthese basiert auf der Verwendung von Thioglycosiden und Sulfoxiden als Galactosyl-Donoren, die sich als hervorragend geeignet für den Aufbau dieses Verknüpfungsmusters erwiesen. Darüber hinaus konnte die Effizienz der Glycosylierungen entscheidend durch die Verwendung neuartiger Substitutionsmuster erhöht werden, die den sterischen Einfluß der genutzten Schutzgruppen berücksichtigt. Weiterhin lassen die aus beta-(1-4)-verknüpften D-Galactose-Einheiten aufgebauten Analoga der Cyclodextrine, die Cyclogalactine, interessante Eigenschaften hinsichtlich ihres Komplexierungsverhaltens erwarten. Für die angestrebte Totalsynthese dieser neuen Cyclooligosaccharide wurden deshalb Methoden zur Generierung von geeigneten linearen Monomeren entwickelt

Tuning the density of zwitterionic polymer brushes on PET fabrics by aminolysis : Effect on antifouling performances

Here, we synthesize zwitterionic polymer brushes on polyester fabrics by atom transfer radical polymerization (ATRP) after a prefunctionalization step involving an aminolysis reaction with ethylenediamine. Aminolysis is an easy method to achieve homogeneous distributions of functional groups on polyester fibers (PET) fabrics. Varying the polymerization time and the prefunctionalization conditions of the reaction, it is possible to tune the amount of water retained over the surface and study its effect on protein adhesion. This study revealed that the polymerization time plays a major role in preventing protein adhesion on the PET surface