Proposed Formulae for Determining Blood Transfusion Requirements in Children with Severe Anaemia

Background: Blood replacement remains a crucial component of the treatment of severe anaemia irrespective of the cause. The transfusion of an adequate amount of blood is important to prevent under- or over-transfusion. Existing formulae used for the calculation of blood transfusion requirements, while being useful, still have deficiencies. The current study aims to evolve simple formulae that can be used in calculating the volume of packed red blood cells (PRBC) required for attaining a specific packed cell volume (PCV) level. Method: A total of 172 patients with severe anaemia [PCV o